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18 April 2022 | Story Leonie Bolleurs | Photo Stephen Collett
Prof Ted Kroon
Prof Ted Kroon from the Department of Physics recently delivered his inaugural lecture on the topic What’s the use of a rainbow on the UFS Bloemfontein Campus.

“A rainbow is a natural phenomenon, the result of the refraction and reflection of the sun’s rays in drops of rain. As far as mankind is concerned, it’s a perfectly useless object and won’t make anyone money. Yet the poet who said, My heart leaps up when I behold a rainbow in the sky, only put into word the feeling of wonder and excitement we all have when we see a rainbow.”

“Every day I see a rainbow in my work; I do not need to wait to see one in the sky,” says Prof Ted Kroon, Professor in the Department of Physics at the University of the Free State (UFS), who used this phenomenon to introduce the topic of his inaugural lecture: What’s the use of a rainbow. 

“Far from being only a colourful spectacle with no practical value, rainbows are useful – and lead to useful things,” he believes. 

According to Prof Kroon, one can find examples of real rainbows and rainbow analogies used not only in everyday life, but also in physics. “Besides it being familiar devices in literature, culture, and even marketing, studies of rainbows can yield practical engineering information and may even help us to find new habitable planets,” he says.

Inspired by the many uses of a rainbow

In his lecture, he discussed the basic features of natural rainbows and how they come about. He also explored how the rainbow gives meaning to colour, and how this relates to the temperature of objects. He looked at an array of instances where the rainbow is used; from depicting the life of a star to indicating that we are sick (a thermometer) or when we need to refill a gas cylinder.
Moreover, Prof Kroon pointed out that rainbows are used in computer chips, stress identification, and to transmit internet data through underwater cables of glass fibre. He also referred to how the rainbow was harnessed as an engineering tool to measure refractive index and characterise fine droplet sprays used in industry. 

He continues, “Remarkably, the science developed to understand the natural rainbow can be redirected and applied to the optical properties of metallic nanoparticles, allowing the development of nanotechnology. Knowing how the natural rainbow works and its limitations, better systems have been developed to produce rainbows. Such rainbows have been used to discover new elements and to determine the age of the universe.”

As a member of an international community of phosphor researchers who are privileged to work with rainbows every day, he has used them to study the light-emitting properties of materials doped with bismuth. With this project – an initiative with the African Laser Centre taking place between 2016 and 2021 – he collaborated with the University of Khartoum in Sudan and trained a number of its postgraduate students. “My role included the guidance of students and the measurement and interpretation of the light-emitting properties of the materials. Our research during this time, considering more than a dozen materials, was summarised in 34 scientific publications that contributed to a greater understanding of bismuth ions as light-emitting materials,” he explains. 

Developing new materials, efficient in emitting blue light

He has been developing luminescent materials since 2006, primarily for general lighting (fluorescent tubes and LEDs) and displays (television, computer, and cellphone screens), as well as niche applications in medical and forensic science. 

As part of his current research, he is examining the effect of plasmonic metal nanoparticles on phosphor light emission. He is also exploring materials that absorb infrared light but emit visible light. “For this, I would like to consider the long-term stability of such materials and develop new materials that are more efficient in emitting particularly blue light,” he says. 

Prof Kroon holds a C2 rating from the National Research Foundation and has published more than 150 articles and book chapters, obtaining a Scopus h-index of 26.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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