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The last days of plenty: Prof Mukwada delivers his inaugural lecture

26 August 2022 | Story NONSINDISO QWABE | Photo Boitumelo Molefe

South Africa is generally regarded as a thirsty country due to water scarcity nationally. Even a rise of 0,5 °C in climate temperatures could have devastating effects on the environment.

Delivering his inaugural lecture on 22 August 2022 – a first for the Qwaqwa Campus in many years – Prof Geofrey Mukwada of the Department of Geography at the University of the Free State (UFS) Qwaqwa Campus painted a picture of the long-term effects of climate change on ecological, social, and economic aspects of the environment. The effects of climate change are being felt in all regions of the world, and the Drakensberg region in particular is beginning to bear the brunt.

Elevation-dependent warming a threat to socio-ecological systems

Introducing his topic, The last days of plenty: an assessment of elevation-dependent warming in the Drakensberg Mountain region between 1980 and 2018 and its potential implications for social-ecological systems in the region and downstream communities, Prof Mukwada said ‘last days’ was a euphemism used figuratively to imply the impending loss of environmental resources in the mountains because of climate change.

According to Prof Mukwada, elevation-dependent warming in the Drakensberg would pose serious implications for the overall rural livelihoods, regional trade, and biodiversity conservation.

“The Drakensberg Mountains is made up of a chain of several mountains and is home to a lot of activities. It is important for rural livelihood, including agriculture, cultivation of different forms, fisheries, and tourism, and if the climate is therefore changing and elevation-dependent warming is taking place, we see a threat to socio-ecological systems in many ways.”

In his lecture, Prof Mukwada discussed the three-decade-long investigation to determine if elevation-dependent warming is taking place at several points of the mountains, and to assess its environmental implications for the region and downstream communities. Using a time-series analysis standardised precipitation and evaporation index (SPEI) and monthly maximum temperature and locational and elevation data, the investigation monitored climate change trends between 1980 and 2018.

Development of research-based solutions

He said results did not confirm the existence of elevation-dependent warming in the Drakensberg Mountain region, but statistically significant evidence has shown that the region is becoming warmer and facing increasing aridity.

“It is worrisome in the sense that even such a small change can have devastating effects on the environment.”

In order to avert these problems, Prof Mukwada said a special climate adaptation plan for the region was necessary. The university plays a key role in this, as it can provide guidance on the process of redefining knowledge, scientific understanding and truth, in order to promote sound mountain development interventions and programmes. “We need to shift towards research-based solutions.”

Prof Mukwada is a C2 NRF-rated researcher with expertise in the application of remote sensing and geographic information systems (GIS) in integrated scientific and multidisciplinary environmental research.

News Archive

Collaboration between UFS and Mayo Clinic to revolutionise cancer treatment

2014-06-27

Attending the lecture were, from the left: Dr Chantel Swart, Prof Lodewyk Kock, Prof Debabrata Mukhopadhyay, Prof James du Preez; back: Prof Pieter van Wyk. Dr Swart, Profs Kock and Du Preez are from the Department of Microbial, Biochemical and Food Biotechnology. Prof Mukhopadhyay is from the Mayo Clinic (US) and Prof Van Wyk is from the Centre for Microscopy at the UFS.
Photo: Supplied

The UFS made a discovery that may have enormous implications for the treatment of diseases in humans.

Since the discovery, the UFS joined forces with the Mayo Clinic in Rochester, US, in the fight against cancer.

In this collective effort, UFS researchers would be able to assist the Mayo team to:
• see how treatment in cancer patients is progressing,
• target treatments more effectively,
• reduce dosages in order to make treatment gentler on the patient,
• track the effectiveness of the chemotherapy drugs used, and
• gain an accurate view of how the cancer is being eliminated.

Prof Lodewyk Kock, Outstanding Professor at the Department of Microbial, Biochemical and Food Biotechnology, and his team incidentally created a technique to use argon gas particles for the first time on biological material to slice open cells to look inside.

The team that supported Prof Kock includes Dr Chantel Swart, Khumisho Dithebe (PhD student), Prof Hendrik Swart (Department of Physics) and Prof Pieter van Wyk (Centre for Microscopy).

Prof Debabrata Mukhopadhyay from the Mayo Clinic in Rochester, US, got to hear about this breakthrough at the UFS and a collaboration between the two institutions was established.

During a visit to the Bloemfontein Campus, Prof Mukhopadhyay explained novel techniques that make use of gold nanoparticles. These particles attach to chemotherapeutic drugs to selectively target cancer cells – dramatically decreasing the side effects to normal human cells.

For these new drugs (coupled to gold nanoparticles) to be accepted into clinical practice, visual and chemical proof is needed, though. This is where the technique developed by the UFS will play a vital role.

With the technique to look inside cells, the composition, location and metabolism of these drugs can be determined. This will aid in a proof of concept for the application of the nano-drugs. Furthermore, it will enable approval for use of these drugs in clinical trials and eventually could revolutionise cancer treatment as a whole.

For video lectures on the technique used, as well as its findings, follow these links:

1. http://vimeo.com/63643628 (Comic version for school kids)

2. http://vimeo.com/61521401 (Detailed version for fellow scientists)

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