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25 August 2022 | Story Leonie Bolleurs | Photo Supplied
Bernedette Muthien
Bernedette Muthien is the author of Rethinking Africa, which critically opens new pathways for decolonial scholarship and the reclamation of indigenous self-definition by women scholars.

“Claim your own agency and power, no matter how challenging the circumstances. Violence and oppression stop with each of us. We ended apartheid. We will end patriarchy. And everyone will benefit from the end of gender and intersecting oppressions, to live their full potential in an equal and nonviolent society. We are making the change; it is coming; always have hope.”

This is the message to women from Bernedette Muthien, Research Fellow in the Office for International Affairs at the University of the Free State (UFS).

For the past 20 years, she has conducted research on intersectional justice, a topic that is both scholarly, accessible to activists and others, and can be used to improve our communities, our country, and the world at large.

Muthien has written more than 200 publications, some translated into European and local languages, on gender, gender violence, HIV, Aids, poverty, and sexualities.

Additionally, she has published widely in peace and security studies, as well as indigenous studies. Some of her other works deal with human rights and justice, specifically the constitution and education in South Africa. "As a scholar and human being and being involved in the last cohort of youth activists against apartheid during the turbulent 1980s, I consider intersectional justice and constitutional rights of critical importance,” she says.

Restoring dignity to our people

One of Muthien’s most recent works, Rethinking Africa, is a collection of chapters by diverse indigenous women – from playwright Sylvia Vollenhoven, to academic Babalwa Magoqwana – reinterpreting our past from various women’s perspectives.

The book, conceived at the start of the pandemic lockdown and produced in less than a year, critically opens new pathways for decolonial scholarship and the reclamation of indigenous self-definition by women scholars. “It is long overdue that, as indigenous women, we write our own herstory, define our own contemporary cultural and socio-economic conditions, and conceive future visions based on our lived realities, which are social and gender equality, matricentric, beyond-heteronormative, based on nonviolence or peace, ecologically responsible, and goddess-loving,” she says. 

It is Muthien's commitment to her women ancestors and contemporary communities that inspired this work, correcting misinterpretations of indigenous knowledge, women's role in society, and colonially influenced patriarchy in our urban areas.

She believes one needs women at the centre of societies, co-creating social values and practices that are humane and nonviolent, that nurture and foster individual and collective growth, that heal and care, that do no harm, and definitely do not exploit. 

“There is enough light in the cosmos for all the stars to shine. One star’s light does not diminish the glitter of other stars, and shining together, all the stars united can be brighter than even the sun. Together, we continue to define our own herstories and scholarship for ourselves, as indigenous peoples in Africa,” Muthien was heard saying at the online launch of Rethinking Africa last year. 

Through this publication, she mostly wanted to convey that women are central to indigenous societies, and that our environment is alive and worthy of respect. In Muthien's view, humans, animals, plants, and the planet should not be exploited in any way but imbued with dignity.

Furthermore, she believes that we need to reclaim these core indigenous values and practices that have been corrupted by colonially inspired patriarchy. “As a result, we will eradicate gender violence and restore dignity to our women, our men, and to our people," she says.

Challenging colonially inspired patriarchy

The intent of Rethinking Africa is to contribute to scholarship. Yet the contributors are from different sectors, writing in diverse styles, making this work accessible to all audiences. “Photographs of sacred sites and rock art, as well as poems by leading indigenous poets, are included in the book, illustrating the indigenous intersections between scholarship, art, creativity, spirituality, and between individual and community,” she explains. 

The work specifically challenges colonially inspired patriarchy, including religious teachings about patriarchy, about the subordination of women, which contradict indigenous wisdoms of equality and women at society’s centre.

Muthien’s work, although challenging for some, does add value, changing people’s lives for the better. For decades, she has worked on consciousness transformation through scholarship and community work. She is of the opinion that mindsets need to change in order to change behaviour and society. “In this way, the change is deep and lasting,” she says. 

She is also a firm believer in less talk, and more strategic and effective action. “In taking action, one first decolonises the mindset; strip it bare of all internalised oppression. Then it is important to re-instil ancient indigenous knowledge, values, and practices. Also offer skills, networks, resources, to communities as they offer their knowledge to scholars.”

“In addition, leave concrete assets for communities,” she says. Muthien tells the story of a family in Andriesvale, deep in the Kalahari, who built their Kalahari Kombuis, which serves as their residence and a tourist entertainment and dining venue, funded by a small group of Dutch feminists who wanted to contribute to reparations. According to her, the building and the family and community thrive to this day.

And importantly, it is key to have compassion. “Always compassion,” she says.

Muthien offered Rethinking Africa as her contribution to the various communities she has served over decades since birth.

• The book is available in bookshops and online, and online around the world.

News Archive

Cardiology Unit involved in evaluation of drug for rare genetic disease
2013-01-04

Front from the left, are: Marinda Karsten (study coordinator and registered nurse),
Laumarie de Wet (clinical technologist), Charmaine Krahenbuhl (study coordinator and radiographer),
Lorinda de Meyer (administrator), Andonia Page (study coordinator and enrolled nurse);
back Dr Gideon Visagie (sub investigator), Dr Derick Aucamp (sub investigagtor),
Prof. Hennie Theron, (principal investigator) and Dr Wilhelm Herbst (sub investigator).
Photo: Supplied
09 January 2013


The Cardiology Research Unit at the University of the Free State (UFS) contributed largely to the evaluation of the drug Juxtapid (lomitapide), which was developed by the Aegerion pharmaceutical company and approved by the FDA (Federal Drug Administration). Together with countries such as die USA, Canada and Italy, the UFS’ Unit recruited and evaluated the most patients (5 of 29) for the study since 2008.  

The drug was evaluated in persons with so-called familial homozygous hypercholesterolemia (HoFH).  

Following its approval by the FDA, Juxtapid is now a new treatment option for patients suffering from HoFH. The drug operates in a unique way which brings about dramatic improvements in cholesterol counts.  

According to Prof. Hennie Theron, Associate Professor in the Department of Cardiology at the UFS and Head of the Cardiology Contract Research Unit, HoFH is a serious, rare genetic disease which affects the function of the receptor responsible for the removal of low-density lipoprotein cholesterol (LDL-C) (“bad” cholesterol) from the body. Damage to the LDL receptor function leads to extremely high levels of blood cholesterol. HoFH patients often develop premature and progressive atherosclerosis, which is a narrowing or blockage of the arteries.  

“HoFH is a genetically transmitted disease and the most severe form of hypercholesterolemia. Patients often need a coronary artery bypass or/and aortic valve replacement before the age of 20. Mortality is extremely high and death often occurs before the third decade of life. Existing conventional cholesterol-lowering medication is unsuccessful in achieving normal target cholesterol values in this group of patients.  

“The only modality for treatment is plasmapheresis (similar to dialysis in patients with renal failure). Even with this type of therapy the results are relatively unsatisfactory because it is very expensive and the plasmapheresis has to be performed on a regular basis.  

“The drug Juxtapid, as currently evaluated, has led to a dramatic reduction in cholesterol values and normal values were achieved in several people. No existing drug is nearly as effective.  

“The drug represents a breakthrough in the treatment of familial homozygous hypercholesterolemia. The fact that it has been approved by the FDA, gives further impetus to the findings,” says Prof. Theron.  

In future further evaluation will be performed in other forms of hypocholesterolemia.  

According to Prof. Theron, the findings of the study, as well as the recent successful FDA evaluation, once again confirms the fact that the UFS’ Cardiology Contract Research Unit is doing outstanding work.  

Since its inception in 1992, the Unit has already been involved in more than 60 multi-centre, international phase 2 and 3 drug studies. Several of these studies, including the abovementioned study, really affected the way in which cardiology functions.  

The UFS’ Cardiology Contract Research Unit is being recognised nationally and internationally for its high quality of work and is constantly approached for their involvement in new studies.  

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