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25 August 2022 | Story Leonie Bolleurs | Photo Supplied
Bernedette Muthien
Bernedette Muthien is the author of Rethinking Africa, which critically opens new pathways for decolonial scholarship and the reclamation of indigenous self-definition by women scholars.

“Claim your own agency and power, no matter how challenging the circumstances. Violence and oppression stop with each of us. We ended apartheid. We will end patriarchy. And everyone will benefit from the end of gender and intersecting oppressions, to live their full potential in an equal and nonviolent society. We are making the change; it is coming; always have hope.”

This is the message to women from Bernedette Muthien, Research Fellow in the Office for International Affairs at the University of the Free State (UFS).

For the past 20 years, she has conducted research on intersectional justice, a topic that is both scholarly, accessible to activists and others, and can be used to improve our communities, our country, and the world at large.

Muthien has written more than 200 publications, some translated into European and local languages, on gender, gender violence, HIV, Aids, poverty, and sexualities.

Additionally, she has published widely in peace and security studies, as well as indigenous studies. Some of her other works deal with human rights and justice, specifically the constitution and education in South Africa. "As a scholar and human being and being involved in the last cohort of youth activists against apartheid during the turbulent 1980s, I consider intersectional justice and constitutional rights of critical importance,” she says.

Restoring dignity to our people

One of Muthien’s most recent works, Rethinking Africa, is a collection of chapters by diverse indigenous women – from playwright Sylvia Vollenhoven, to academic Babalwa Magoqwana – reinterpreting our past from various women’s perspectives.

The book, conceived at the start of the pandemic lockdown and produced in less than a year, critically opens new pathways for decolonial scholarship and the reclamation of indigenous self-definition by women scholars. “It is long overdue that, as indigenous women, we write our own herstory, define our own contemporary cultural and socio-economic conditions, and conceive future visions based on our lived realities, which are social and gender equality, matricentric, beyond-heteronormative, based on nonviolence or peace, ecologically responsible, and goddess-loving,” she says. 

It is Muthien's commitment to her women ancestors and contemporary communities that inspired this work, correcting misinterpretations of indigenous knowledge, women's role in society, and colonially influenced patriarchy in our urban areas.

She believes one needs women at the centre of societies, co-creating social values and practices that are humane and nonviolent, that nurture and foster individual and collective growth, that heal and care, that do no harm, and definitely do not exploit. 

“There is enough light in the cosmos for all the stars to shine. One star’s light does not diminish the glitter of other stars, and shining together, all the stars united can be brighter than even the sun. Together, we continue to define our own herstories and scholarship for ourselves, as indigenous peoples in Africa,” Muthien was heard saying at the online launch of Rethinking Africa last year. 

Through this publication, she mostly wanted to convey that women are central to indigenous societies, and that our environment is alive and worthy of respect. In Muthien's view, humans, animals, plants, and the planet should not be exploited in any way but imbued with dignity.

Furthermore, she believes that we need to reclaim these core indigenous values and practices that have been corrupted by colonially inspired patriarchy. “As a result, we will eradicate gender violence and restore dignity to our women, our men, and to our people," she says.

Challenging colonially inspired patriarchy

The intent of Rethinking Africa is to contribute to scholarship. Yet the contributors are from different sectors, writing in diverse styles, making this work accessible to all audiences. “Photographs of sacred sites and rock art, as well as poems by leading indigenous poets, are included in the book, illustrating the indigenous intersections between scholarship, art, creativity, spirituality, and between individual and community,” she explains. 

The work specifically challenges colonially inspired patriarchy, including religious teachings about patriarchy, about the subordination of women, which contradict indigenous wisdoms of equality and women at society’s centre.

Muthien’s work, although challenging for some, does add value, changing people’s lives for the better. For decades, she has worked on consciousness transformation through scholarship and community work. She is of the opinion that mindsets need to change in order to change behaviour and society. “In this way, the change is deep and lasting,” she says. 

She is also a firm believer in less talk, and more strategic and effective action. “In taking action, one first decolonises the mindset; strip it bare of all internalised oppression. Then it is important to re-instil ancient indigenous knowledge, values, and practices. Also offer skills, networks, resources, to communities as they offer their knowledge to scholars.”

“In addition, leave concrete assets for communities,” she says. Muthien tells the story of a family in Andriesvale, deep in the Kalahari, who built their Kalahari Kombuis, which serves as their residence and a tourist entertainment and dining venue, funded by a small group of Dutch feminists who wanted to contribute to reparations. According to her, the building and the family and community thrive to this day.

And importantly, it is key to have compassion. “Always compassion,” she says.

Muthien offered Rethinking Africa as her contribution to the various communities she has served over decades since birth.

• The book is available in bookshops and online, and online around the world.

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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