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12 December 2022 | Story Leonie Bolleurs | Photo Leonie Bolleurs
Dr Karen Venter
Dr Venter received her PhD at the December graduation ceremonies. She focused on addressing societal challenges through the practice of engaged scholarship in community-university research partnerships for the common good.

When asked what inspired her to pursue a PhD, Dr Karen Venter, Head of the Division of Service Learning in the Directorate Community Engagement at the University of the Free State (UFS), said she wanted to make a difference in addressing societal challenges through the practice of engaged scholarship in community-university research partnerships for the common good. 

“Also, I love to learn and share knowledge – and that is exactly what I did in this PhD, titled: An integrated service-learning praxis approach for flourishment of professional development in community-higher education partnerships.” 

She explains, “My five-articles-style thesis explored the contribution of an integrated service-learning praxis approach towards the flourishment of engaged scholarship in community-higher education partnerships. The approach combined community engaged service-learning (CESL), appreciative inquiry and appreciative leadership, to advance the praxis of engaged scholarship. The study was demarcated in the field of higher education, applied in the discipline of nursing education, and contextually bound to three interrelated action research cycles and settings – for international, national, and local level engagement.”

Community members participate in the research journey

“The intent of the study was to recognise the community-led action learning of community member participants at the core action learning set,” says Dr Venter. 

The study followed a participatory action learning and action research methodology. During her research journey, she was joined by members of the community, specifically from Bloemshelter – a shelter for the homeless. “They co-constructed and completed a four-year community-led action learning pathway to holistic development (spiritual, personal, professional), which brought about holistic social change and well-being in their livelihood, moving from dependence on others to establishing viable multiple micro-enterprises,” she says.

The UFS affiliated with GULL to reward the community member participants’ action learning. “Already in 2019, GULL certified their action learning with a Professional Bachelor’s degree, while I still had to document the action research, and only now received the PhD,” says Dr Venter. 

“I am grateful to all the participants who co-created action-oriented knowledge with me in the study, from international, to national, to local level of engagement.”

Integrating a PhD with work and life

A PhD requires a lot of hard work and effort, to the point that the lines between studies, work, and life become blurred. Dr Venter acknowledged that she tried to balance work/life and study, but “I was not very good at it”. 
Passion, patience, peace, perseverance, positivity, and prayer are good principles to maintain when you are in the process of completing a PhD. – Dr Karen Venter 

She elaborates, “Studying became an integrated part of my work and life.  For the duration of my studies, I started working at 03:00 and I also did not watch any television.” She did, however, make time for herself by joining the wellness workout programme presented by the UFS, enjoyed gardening, and playing with her grandchildren. “I also tried to rest one day over weekends, and made time to praise and worship, which energised me for the next week,” she adds. 

“Passion, patience, peace, perseverance, positivity, and prayer are good principles to maintain when you are in the process of completing a PhD, she believes. 

Dr Venter says that although writing a PhD is indeed lonely, it is also an exciting journey, “especially when you reach those moments of breakthrough that can only come to life after deep reflection.” She also describes it as a deep spiritual journey. “Almost like walking in and out of a labyrinth – and where many hours become equal to a breath.

She is very grateful to her supervisors, Dr Somarie Holtzhausen, Prof Mabel Erasmus, and Dr Elanie Myburgh. “I deeply honour and salute you for your unconditional and continuous coaching, compassion, and care – guiding, supporting, motivating, mentoring, and keeping me grounded until I completed the journey.”

 

 


News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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