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06 December 2022 | Story André Damons | Photo Sonia Small
Dr Nicholas Pearce
Prof Nicholas Pearce has joined the Faculty of Health Sciences’ management team after being appointed Head of the School of Clinical Medicine. Prof Pearce is the former Head of the Department of Surgery at the UFS and led the Universitas Hospital’s COVID-19 Task Team.

During the height of the COVID-19 pandemic, Prof Nicholas Pearce led the COVID-19 Task Team of the Universitas Academic Hospital, ensuring that the hospital not only had enough Personal protective equipment (PPEs) and beds for patients, but also that the vaccination process ran smoothly. Now, the Best Doctor of the Year for 2022 – as named during this year’s National Annual Batho Pele Excellence Awards (NBPEA) – will lead the School of Clinical Medicine in the Faculty of Health Sciences at the University of the Free State (UFS).

Prof Pearce, former Head of the Department of Surgery at the UFS who served the faculty in multiple capacities over a long period, took up this position on 1 December 2022 – a position he is looking forward to.  

Create world-class doctors, maximise students’ full potential

“I’m excited about taking up my new position as Head of the School of Clinical Medicine. This is a role that comes with huge responsibility, and my vision is to create world-class doctors and to maximise each student’s full potential.  We, as university, are a national asset and need to grow and develop to be of service to the future of our country.  So, to lead a school with such a prestigious history is truly a privilege,” says Prof Pearce. 

According to him, the goal for the Medical School in the next five years should be determined by three main core drivers: service delivery, research, and teaching and training. He would like to be in a stronger position, with innovation that can produce world-class doctors (both undergraduate and postgraduate). 

If you look at the strategic plan of the UFS, says Prof Pearce, it is clear that, under the leadership of current Rector and Vice-Chancellor, Prof Francis Petersen, a period of regeneration and innovation is upon the university. Tied to this concept is the idea of self-evaluation and improvement. The idea of challenges and coming up with solutions excites him.  

“I think for a while, my main aim will be to bring the university, the provincial Department of Health, and the school in alignment, ensuring that we are all pulling in the same direction to achieve the same goal.”  

“At the end of the day, the goal here is to provide quality health care to the people of South Africa, while the Department of Health, the university, and society each function in different environments – coming together and understanding each other’s needs and having a common goal – excellent health care in this country for all our citizens.”

Lessons learned from surgery and running COVID-19 task teams

Prof Pearce, who was awarded the UFS Chancellor’s Medal for outstanding service during the April graduation ceremonies, says lessons learned from being both a surgeon and running COVID-19 task teams, are that strategic organisational processes need to be in place – systems strengthened, the policies and procedures adapted, and comprehensive planning taking place. 

However, he says, one must also bear in mind that we have a history of very high academic standards in the School of Clinical Medicine, so you want to improve on that rather than go backwards.

“I learned a lot from surgery and COVID-19 that will equip me in future. COVID-19 taught me about organisational management, disaster management, funding, resource management, people management skills, development, etc.  
“Running the Department of Surgery, one of the largest departments in the faculty with multiple inputs and personalities, has taught me that you are only as strong as the team behind you. I have an amazing team behind me in this new role, whether it is the dean, vice-dean, heads of department, administration, rectorate, and so forth.” 

He will continue to work at the Universitas Hospital; however, being fully employed by the university, he will only be doing some calls and working over weekends.  

“As a surgeon, theatre has always been my safe haven, my place of meditation, my place of peace, and I am sad to say goodbye to surgery and the Department of Surgery – it has been loyal, and I am grateful to everyone in the department; but I think as with all good things, there is a time to come and a time to go.”

News Archive

Nanotechnology breakthrough at UFS
2010-08-19

 Ph.D students, Chantel Swart and Ntsoaki Leeuw


Scientists at the University of the Free State (UFS) made an important breakthrough in the use of nanotechnology in medical and biological research. The UFS team’s research has been accepted for publication by the internationally accredited Canadian Journal of Microbiology.

The UFS study dissected yeast cells exposed to over-used cooking oil by peeling microscopically thin layers off the yeast cells through the use of nanotechnology.

The yeast cells were enlarged thousands of times to study what was going on inside the cells, whilst at the same time establishing the chemical elements the cells are composed of. This was done by making microscopically small surgical incisions into the cell walls.

This groundbreaking research opens up a host of new uses for nanotechnology, as it was the first study ever in which biological cells were surgically manipulated and at the same time elemental analysis performed through nanotechnology. According to Prof. Lodewyk Kock, head of the Division Lipid Biotechnology at the UFS, the study has far reaching implications for biological and medical research.

The research was the result of collaboration between the Department of Microbial, Biochemical and Food Biotechnology, the Department of Physics (under the leadership of Prof. Hendrik Swart) and the Centre for Microscopy (under the leadership of Prof.Pieter van Wyk).

Two Ph.D. students, Chantel Swart and Ntsoaki Leeuw, overseen by professors Kock and Van Wyk, managed to successfully prepare yeast that was exposed to over-used cooking oil (used for deep frying of food) for this first ever method of nanotechnological research.

According to Prof. Kock, a single yeast cell is approximately 5 micrometres long. “A micrometre is one millionth of a metre – in laymen’s terms, even less than the diameter of a single hair – and completely invisible to the human eye.”

Through the use of nanotechnology, the chemical composition of the surface of the yeast cells could be established by making a surgical incision into the surface. The cells could be peeled off in layers of approximately three (3) nanometres at a time to establish the effect of the oil on the yeast cell’s composition. A nanometre is one thousandth of a micrometre.

Each cell was enlarged by between 40 000 and 50 000 times. This was done by using the Department of Physics’ PHI700 Scanning Auger Nanoprobe linked to a Scanning Electron Microscope and Argon-etching. Under the guidance of Prof. Swart, Mss. Swart en Leeuw could dissect the surfaces of yeast cells exposed to over-used cooking oil. 

The study noted wart like outgrowths - some only a few nanometres in diameter – on the cell surfaces. Research concluded that these outgrowths were caused by the oil. The exposure to the oil also drastically hampered the growth of the yeast cells. (See figure 1)  

Researchers worldwide have warned about the over-usage of cooking oil for deep frying of food, as it can be linked to the cause of diseases like cancer. The over-usage of cooking oil in the preparation of food is therefore strictly regulated by laws worldwide.

The UFS-research doesn’t only show that over-used cooking oil is harmful to micro-organisms like yeast, but also suggests how nanotechnology can be used in biological and medical research on, amongst others, cancer cells.

 

Figure 1. Yeast cells exposed to over-used cooking oil. Wart like protuberances/ outgrowths (WP) is clearly visible on the surfaces of the elongated yeast cells. With the use of nanotechnology, it is possible to peel off the warts – some with a diameter of only a few nanometres – in layers only a few nanometres thick. At the same time, the 3D-structure of the warts as well as its chemical composition can be established.  

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za  
18 August 2010
 

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