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09 December 2022 | Story Leonie Bolleurs | Photo Leonie Bolleurs
Dr Thomas Sekyi-Ampah
Dr Thomas Sekyi-Ampah, who recently received his PhD in Urban and Regional Planning at the UFS December graduation ceremonies.

“I am extremely glad that I was successful in obtaining my PhD degree. Learning is a lifelong experience, and the joy of this undertaking is immense. I will encourage others to pursue this goal later in their lives if they so desire,” said Dr Thomas Eric Sekyi-Ampah, who received his PhD degree in the Department of Urban and Regional Planning at the University of the Free State (UFS) – just more than two weeks before his 74th birthday. 

He completed his master’s degree at the UFS and decided to also pursue a PhD at the same institution, focusing on the tension between traditional leaders and the municipal planning process around the Spatial Planning and Land Use Management Act 2013 (SPLUMA), the role traditional leaders play in nature conservation, and the limitations of municipal spatial governance due to inadequate resources. In his thesis, titled: Towards a sustainable and transformative spatial governance system for municipalities with traditional leaders: A case study of Alfred Nzo District Municipality, Eastern Cape, Dr Sekyi-Ampah investigates the potential for inclusive and sustainable spatial governance in this municipal district.

His supervisor since 2018, Prof Verna Nel, Professor in the Department of Urban and Regional Planning, said the process required tenacity and hard work. “I admire his persistence.”

Impacting service delivery

Dr Sekyi-Ampah describes the Alfred Nzo District as “a deeply rural area, characterised by subsistence agriculture, where longstanding traditions and customs prevail”.

“The legacy of the 1913 Land Act and subsequent apartheid policies are evident in the pervasive poverty and high dependence on social grants,” he added. 

“For me, it was appropriate to explore the nature of the existing spatial governance and development challenges of towns and the traditional authority areas within this municipal district, as well as the relationships between the municipalities and the traditional authorities,” he said.

He continued: “Very large areas of traditional lands are located in environmentally sensitive zones. Thus, planning that takes cognisance of the environment should be paramount.”

After interviewing municipal officials, traditional leaders, local businesses, and planners with knowledge about the region, he found that although the traditional leaders have antagonistic feelings towards the implementation of SPLUMA, there is sufficient goodwill for cooperation with the local governments in the district. While the necessary plans and policies are in place, the main obstacles are the constraints experienced by the municipalities – staff, finances, and an unstable political environment.

He also found that implementing the Spatial Development Framework (SDF) in the traditional areas is a challenge, since municipalities do not control land allocation. “Planners are excluded from land allocation; thus, there is no adherence to the provisions of the SDF. This impacts service delivery, disaster management, and the judicious use of the environment in the traditional areas,” he said.

Improving sustainability of the area

Dr Sekyi-Ampah believes that he can add value through his research. It can improve the sustainability of the area if these constraints are addressed, and if traditional leaders are included in the planning and land use management processes. Ultimately, this can alleviate the plight of residents.

“I recommend the Department of Urban and Regional Planning to any prospective student, because it has a team of academics and support staff that will guarantee success for prospective students who are prepared to put in the requisite effort,” said Dr Sekyi-Ampah.

He is looking forward to continuing his research and to mentor prospective students based on the experience and wealth of knowledge obtained from this research and his experience as a town and regional planner.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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