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24 February 2022 | Story Leonie Bolleurs | Photo Supplied
New Paed Profs
Three senior consultants in the Department of Paediatrics and Child Health were recently promoted to associated professor. From the left are Profs Jan du Plessis, Ute Hallbauer, and David Griessel.

“Dedicated, consistent hard work, a high standard of work ethics, specialised patient care, and high-quality research outputs.” These were the words used by the Head of the Department of Paediatrics and Child Health at the University of the Free State (UFS), Dr Lizzy Tabane, to describe three of its senior consultants who were recently promoted to associate professor.

The three academics who are making a difference in the lives of hundreds of people on a daily basis, are Profs Ute Hallbauer, David Griessel, and Jan du Plessis.

Drug-resistant tuberculosis and diabetics

Prof Hallbauer, the first female professor in the department, works as a consultant senior paediatrician in the Pelonomi and Universitas hospitals. She has proven herself to be a champion in rendering a comprehensive service in paediatric infectious diseases, including paediatric tuberculosis and the specialised area of paediatric drug-resistant tuberculosis (TB).

According to Dr Tabane, when Prof Hallbauer started working with children with drug-resistant tuberculosis in the province in 2006, she reached a success rate of more than 95% compliance and cure of this disease.

It was good to reap the benefits of improved diagnostics and treatment for this disease, says Prof Hallbauer, who initially did not like the topic of TB. “Once my knowledge improved and I diagnosed and managed some difficult situations, it was amazing to see what there is to learn and how much one can do to help children affected by TB. It is worrying that the disease is still so prevalent among children in South Africa,” she says.

Prof Hallbauer also renders a comprehensive service in paediatric diabetes in the Free State and assists doctors from the Northern Cape with advice. Her work includes contributing to the training of dietetics students, where she focuses on food choices for children with diabetes.

“Children with diabetes have taught me a lot of patience. I have learnt to individualise my approach to each child/parent and to never give up and to teach, re-teach and re-teach. Working with the Department of Dietetics and Nutrition to run a Kids Diabetes Camp every year has been a wonderful experience which has benefited everyone: the children, the students, the teachers,” says Prof Hallbauer.

Developmental paediatrics and autism spectrum conditions

Prof Griessel is currently one of two neurodevelopmental paediatricians in the Free State and Northern Cape area and is playing a key role in raising awareness about autism and autism spectrum disorders, both at national and international level. This led to him being elected as a member of the National Executive Committee of Autism South Africa and the Global Senior Leader Committee representing South Africa at the leading world society for autism research, namely the International Society for Autism Research. He was also one of the founders of the Autism Support Centre at the UFS and recently played a significant role in opening the School for Autism just outside Bloemfontein.

He is a firm believer in the critical importance of early child development to thrive in life. The work he is doing has embedded autism in the broader context of child development and is based on recent work in the basic sciences on childhood brain development.

“I am humbled to have interacted with so many autistic adults, young people, children, and families living with autism, who taught me about the real strengths of diversity and demonstrated the courage to persist in the face of adversity,” says Prof Griessel, who finds pleasure in interaction with children and young adults with autism. “Their emotions and feelings come from a pure place and motivate me to continue to be of service,” he says.

Paediatric oncology and paediatric haematology

One of the youngest paediatricians to be promoted to associate professor in the department is Prof Du Plessis, who has proven himself to be a champion in rendering a comprehensive and multidisciplinary service in the field of paediatric oncology and paediatric haematology, with a particular focus on palliative care.

“I always wanted to work with children and their families, and the holistic approach enticed me. It is a privilege to walk the cancer journey with these children and their families, from diagnosis to sometimes the end of life and thereafter.”

“Children are amazing, they have so much joy and unconditional love, and the oncology children are in a completely different league. Where else would you find children calling you their ‘pappa’ or a 15-year-old black girl telling the whole school ‘I have a white father’. It is such a privilege,” he says.

Prof Du Plessis, who was also rated the best lecturer by the medical students in 2020, says besides his fondness for working with children and their families, he unexpectedly fell in love with student teaching. “It is a huge responsibility, but so rewarding to play a small role in shaping the minds of tomorrow’s doctors. It is amazing to witness them experiencing the light-bulb moments and rekindle a passion for the occupation by just spending time with them and being an example of what it looks and feels like to enjoy your work.”

News Archive

Champagne and cancer have more in common than you might think
2013-05-08

 

Photo: Supplied
08 May 2013

No, a glass of champagne will not cure cancer....

…But they have more in common than you might think.

Researchers from the Departments of Microbial Biochemical and Food Biotechnology, Physics and the Centre for Microscopy at the University of the Free State in South Africa were recently exploring the properties of yeast cells in wine and food to find out more of how yeast was able to manufacture the gas that caused bread to rise, champagne to fizz and traditional beer to foam. And the discovery they made is a breakthrough that may have enormous implications for the treatment of diseases in humans.

The team discovered that they could slice open cells with argon gas particles, and look inside. They were surprised to find a maze of tiny passages like gas chambers that allowed each cell to ‘breathe.’ It is this tiny set of ‘lungs’ that puts the bubbles in your bubbly and the bounce in your bread.

But it was the technique that the researchers used to open up the cells that caught the attention of the scientists at the Mayo Clinic (Tumor Angiogenesis and Vascular Biology Research Centre) in the US.

Using this technology, they ultimately aim to peer inside cells taken from a cancer patient to see how treatment was progressing. In this way they would be able to assist the Mayo team to target treatments more effectively, reduce dosages in order to make treatment gentler on the patient, and have an accurate view of how the cancer was being eliminated.

“Yes, we are working with the Mayo Clinic,” said Profes Lodewyk Kock from the Microbial, Biochemical and Food Biotechnology Department at the UFS.

“This technique we developed has enormous potential for cell research, whether it is for cancer treatment or any other investigation into the working of cells. Through nanotechnology, and our own invention called Auger-architectomics, we are able to see where no-one has been able to see before.”

The team of Prof Kock including Dr Chantel Swart, Kumisho Dithebe, Prof Hendrik Swart (Physics, UFS) and Prof Pieter van Wyk (Centre for Microscopy, UFS) unlocked the ‘missing link’ that explains the existence of bubbles inside yeasts, and incidentally have created a possible technique for tracking drug and chemotherapy treatment in human cells.

Their work has been published recently in FEMS Yeast Research, the leading international journal on yeast research. In addition, their discovery has been selected for display on the cover page of all 2013 issues of this journal.

One can most certainly raise a glass of champagne to celebrate that!

There are links for video lectures on the technique used and findings on the Internet at:

1. http://vimeo.com/63643628 (Comic version for school kids)

2. http://vimeo.com/61521401 (Detailed version for fellow scientists)

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