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24 February 2022 | Story Leonie Bolleurs | Photo Supplied
New Paed Profs
Three senior consultants in the Department of Paediatrics and Child Health were recently promoted to associated professor. From the left are Profs Jan du Plessis, Ute Hallbauer, and David Griessel.

“Dedicated, consistent hard work, a high standard of work ethics, specialised patient care, and high-quality research outputs.” These were the words used by the Head of the Department of Paediatrics and Child Health at the University of the Free State (UFS), Dr Lizzy Tabane, to describe three of its senior consultants who were recently promoted to associate professor.

The three academics who are making a difference in the lives of hundreds of people on a daily basis, are Profs Ute Hallbauer, David Griessel, and Jan du Plessis.

Drug-resistant tuberculosis and diabetics

Prof Hallbauer, the first female professor in the department, works as a consultant senior paediatrician in the Pelonomi and Universitas hospitals. She has proven herself to be a champion in rendering a comprehensive service in paediatric infectious diseases, including paediatric tuberculosis and the specialised area of paediatric drug-resistant tuberculosis (TB).

According to Dr Tabane, when Prof Hallbauer started working with children with drug-resistant tuberculosis in the province in 2006, she reached a success rate of more than 95% compliance and cure of this disease.

It was good to reap the benefits of improved diagnostics and treatment for this disease, says Prof Hallbauer, who initially did not like the topic of TB. “Once my knowledge improved and I diagnosed and managed some difficult situations, it was amazing to see what there is to learn and how much one can do to help children affected by TB. It is worrying that the disease is still so prevalent among children in South Africa,” she says.

Prof Hallbauer also renders a comprehensive service in paediatric diabetes in the Free State and assists doctors from the Northern Cape with advice. Her work includes contributing to the training of dietetics students, where she focuses on food choices for children with diabetes.

“Children with diabetes have taught me a lot of patience. I have learnt to individualise my approach to each child/parent and to never give up and to teach, re-teach and re-teach. Working with the Department of Dietetics and Nutrition to run a Kids Diabetes Camp every year has been a wonderful experience which has benefited everyone: the children, the students, the teachers,” says Prof Hallbauer.

Developmental paediatrics and autism spectrum conditions

Prof Griessel is currently one of two neurodevelopmental paediatricians in the Free State and Northern Cape area and is playing a key role in raising awareness about autism and autism spectrum disorders, both at national and international level. This led to him being elected as a member of the National Executive Committee of Autism South Africa and the Global Senior Leader Committee representing South Africa at the leading world society for autism research, namely the International Society for Autism Research. He was also one of the founders of the Autism Support Centre at the UFS and recently played a significant role in opening the School for Autism just outside Bloemfontein.

He is a firm believer in the critical importance of early child development to thrive in life. The work he is doing has embedded autism in the broader context of child development and is based on recent work in the basic sciences on childhood brain development.

“I am humbled to have interacted with so many autistic adults, young people, children, and families living with autism, who taught me about the real strengths of diversity and demonstrated the courage to persist in the face of adversity,” says Prof Griessel, who finds pleasure in interaction with children and young adults with autism. “Their emotions and feelings come from a pure place and motivate me to continue to be of service,” he says.

Paediatric oncology and paediatric haematology

One of the youngest paediatricians to be promoted to associate professor in the department is Prof Du Plessis, who has proven himself to be a champion in rendering a comprehensive and multidisciplinary service in the field of paediatric oncology and paediatric haematology, with a particular focus on palliative care.

“I always wanted to work with children and their families, and the holistic approach enticed me. It is a privilege to walk the cancer journey with these children and their families, from diagnosis to sometimes the end of life and thereafter.”

“Children are amazing, they have so much joy and unconditional love, and the oncology children are in a completely different league. Where else would you find children calling you their ‘pappa’ or a 15-year-old black girl telling the whole school ‘I have a white father’. It is such a privilege,” he says.

Prof Du Plessis, who was also rated the best lecturer by the medical students in 2020, says besides his fondness for working with children and their families, he unexpectedly fell in love with student teaching. “It is a huge responsibility, but so rewarding to play a small role in shaping the minds of tomorrow’s doctors. It is amazing to witness them experiencing the light-bulb moments and rekindle a passion for the occupation by just spending time with them and being an example of what it looks and feels like to enjoy your work.”

News Archive

Stem cell research and human cloning: legal and ethical focal points
2004-07-29

   

(Summary of the inaugural lecture of Prof Hennie Oosthuizen, from the Department of Criminal and Medical Law at the Faculty of Law of the University of the Free State.)

 

In the light of stem cell research, research on embryo’s and human cloning it will be fatal for legal advisors and researchers in South Africa to ignore the benefits that new bio-medical development, through research, contain for this country.

Legal advisors across the world have various views on stem cell research and human cloning. In the USA there is no legislation that regulates stem cell research but a number of States adopted legislation that approves stem cell research. The British Parlement gave permission for research on embryonic stem cells, but determined that it must be monitored closely and the European Union is of the opinion that it will open a door for race purification and commercial exploitation of human beings.

In South Africa the Bill on National Health makes provision for therapeutical and non therapeutical research. It also makes provision for therapeutical embryonical stem cell research on fetuses, which is not older than 14 days, as well as for therapeutical cloning under certain circumstances subject to the approval of the Minister. The Bill prohibits reproductive cloning.

Research on human embrio’s is a very controversial issue, here and in the rest of the world.

Researchers believe that the use of stem cell therapy could help to side-step the rejection of newly transplanted organs and tissue and if a bank for stem cell could be built, the shortage of organs for transplants would become something of the past. Stem cells could also be used for healing of Alzheimer’s, Parkinson’s and spinal injuries.

Sources from which stem cells are obtained could also lead to further ethical issues. Stem cells are harvested from mature human cells and embryonic stem cells. Another source to be utilised is to take egg cells from the ovaries of aborted fetuses. This will be morally unacceptable for those against abortions. Linking a financial incentive to that could become more of a controversial issue because the woman’s decision to abort could be influenced. The ideal would be to rather use human fetus tissue from spontaneous abortions or extra-uterine pregnancies than induced abortions.

The potential to obtain stem cells from the blood of the umbilical cord, bone-marrow and fetus tissue and for these cells to arrange themselves is known for quite some time. Blood from the umbilical cord contains many stem cells, which is the origin of the body’s immune and blood system. It is beneficial to bank the blood of a newborn baby’s umbilical cord. Through stem cell transplants the baby or another family member’s life could be saved from future illnesses such as anemia, leukemia and metabolic storing disabilities as well as certain generic immuno disabilities.

The possibility to withdraw stem cells from human embrio’s and to grow them is more useable because it has more treatment possibilities.

With the birth of Dolly the sheep, communities strongly expressed their concern about the possibility that a new cloning technique such as the replacement of the core of a cell will be used in human reproduction. Embryonic splitting and core replacement are two well known techniques that are associated with the cloning process.

I differentiate between reproductive cloning – to create a cloned human embryo with the aim to bring about a pregnancy of a child that is identical to another individual – and therapeutically cloning – to create a cloned human embryo for research purposes and for healing human illnesses.

Worldwide people are debating whether to proceed with therapeutical cloning. There are people for and against it. The biggest ethical objection against therapeutical cloning is the termination of the development of a potential human being.

Children born from cloning will differ from each other. Factors such as the uterus environment and the environment in which the child is growing up will play a role. Cloning create unique children that will grow up to be unique individuals, just like me and you that will develop into a person, just like you and me. If we understand this scientific fact, most arguments against human cloning will disappear.

Infertility can be treated through in vitro conception. This process does not work for everyone. For some cloning is a revolutionary treatment method because it is the only method that does not require patients to produce sperm and egg cells. The same arguments that were used against in vitro conception in the past are now being used against cloning. It is years later and in vitro cloning is generally applied and accepted by society. I am of the opinion that the same will happen with regard to human cloning.

There is an argument that cloning must be prohibited because it is unsafe. Distorted ideas in this regard were proven wrong. Are these distorted ideas justified to question the safety of cloning and the cloning process you may ask. The answer, according to me, is a definite no. Human cloning does have many advantages. That includes assistance with infertility, prevention of Down Syndrome and recovery from leukemia.

 

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