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24 February 2022 | Story Leonie Bolleurs | Photo Supplied
New Paed Profs
Three senior consultants in the Department of Paediatrics and Child Health were recently promoted to associated professor. From the left are Profs Jan du Plessis, Ute Hallbauer, and David Griessel.

“Dedicated, consistent hard work, a high standard of work ethics, specialised patient care, and high-quality research outputs.” These were the words used by the Head of the Department of Paediatrics and Child Health at the University of the Free State (UFS), Dr Lizzy Tabane, to describe three of its senior consultants who were recently promoted to associate professor.

The three academics who are making a difference in the lives of hundreds of people on a daily basis, are Profs Ute Hallbauer, David Griessel, and Jan du Plessis.

Drug-resistant tuberculosis and diabetics

Prof Hallbauer, the first female professor in the department, works as a consultant senior paediatrician in the Pelonomi and Universitas hospitals. She has proven herself to be a champion in rendering a comprehensive service in paediatric infectious diseases, including paediatric tuberculosis and the specialised area of paediatric drug-resistant tuberculosis (TB).

According to Dr Tabane, when Prof Hallbauer started working with children with drug-resistant tuberculosis in the province in 2006, she reached a success rate of more than 95% compliance and cure of this disease.

It was good to reap the benefits of improved diagnostics and treatment for this disease, says Prof Hallbauer, who initially did not like the topic of TB. “Once my knowledge improved and I diagnosed and managed some difficult situations, it was amazing to see what there is to learn and how much one can do to help children affected by TB. It is worrying that the disease is still so prevalent among children in South Africa,” she says.

Prof Hallbauer also renders a comprehensive service in paediatric diabetes in the Free State and assists doctors from the Northern Cape with advice. Her work includes contributing to the training of dietetics students, where she focuses on food choices for children with diabetes.

“Children with diabetes have taught me a lot of patience. I have learnt to individualise my approach to each child/parent and to never give up and to teach, re-teach and re-teach. Working with the Department of Dietetics and Nutrition to run a Kids Diabetes Camp every year has been a wonderful experience which has benefited everyone: the children, the students, the teachers,” says Prof Hallbauer.

Developmental paediatrics and autism spectrum conditions

Prof Griessel is currently one of two neurodevelopmental paediatricians in the Free State and Northern Cape area and is playing a key role in raising awareness about autism and autism spectrum disorders, both at national and international level. This led to him being elected as a member of the National Executive Committee of Autism South Africa and the Global Senior Leader Committee representing South Africa at the leading world society for autism research, namely the International Society for Autism Research. He was also one of the founders of the Autism Support Centre at the UFS and recently played a significant role in opening the School for Autism just outside Bloemfontein.

He is a firm believer in the critical importance of early child development to thrive in life. The work he is doing has embedded autism in the broader context of child development and is based on recent work in the basic sciences on childhood brain development.

“I am humbled to have interacted with so many autistic adults, young people, children, and families living with autism, who taught me about the real strengths of diversity and demonstrated the courage to persist in the face of adversity,” says Prof Griessel, who finds pleasure in interaction with children and young adults with autism. “Their emotions and feelings come from a pure place and motivate me to continue to be of service,” he says.

Paediatric oncology and paediatric haematology

One of the youngest paediatricians to be promoted to associate professor in the department is Prof Du Plessis, who has proven himself to be a champion in rendering a comprehensive and multidisciplinary service in the field of paediatric oncology and paediatric haematology, with a particular focus on palliative care.

“I always wanted to work with children and their families, and the holistic approach enticed me. It is a privilege to walk the cancer journey with these children and their families, from diagnosis to sometimes the end of life and thereafter.”

“Children are amazing, they have so much joy and unconditional love, and the oncology children are in a completely different league. Where else would you find children calling you their ‘pappa’ or a 15-year-old black girl telling the whole school ‘I have a white father’. It is such a privilege,” he says.

Prof Du Plessis, who was also rated the best lecturer by the medical students in 2020, says besides his fondness for working with children and their families, he unexpectedly fell in love with student teaching. “It is a huge responsibility, but so rewarding to play a small role in shaping the minds of tomorrow’s doctors. It is amazing to witness them experiencing the light-bulb moments and rekindle a passion for the occupation by just spending time with them and being an example of what it looks and feels like to enjoy your work.”

News Archive

Researcher part of project aimed at producing third-generation biofuels from microalgae in Germany
2016-05-09

Description: Novagreen bioreactor  Tags: Novagreen bioreactor

Some of the researchers and technicians among the tubes of the Novagreen bioreactor (Prof Grobbelaar on left)

A researcher from the University of the Free State (UFS), Prof Johan Grobbelaar, was invited to join a group of scientists recently at the Institute for Bio- and Geo-Sciences of the Research Centre Jülich, in Germany, where microalgae are used for lipid (oil) production, and then converted to kerosene for the aviation industry.

The project is probably the first of its kind to address bio-fuel production from microalgae on such a large scale.  

“The potential of algae as a fuel source is undisputed, because it was these photoautotrophic micro-organisms that were fixing sunlight energy into lipids for millions of years, generating the petroleum reserves that modern human civilisation uses today.  However, these reserves are finite, so the challenge is marrying biology with technology to produce economically-competitive fuels without harming the environment and compromising our food security.  The fundamental ability that microalgae have to produce energy-rich biomass from CO2, nutrients, and sunlight through photosynthesis for biofuels, is commonly referred to as the Third-Generation Biofuels (3G),” said Prof Grobbelaar.

The key compounds used for bio-diesel and kerosene production are the lipids and, more particularly, the triacylglyserols commonly referred to as TAGs.  These lipids, once extracted, need to be trans-esterified for biodiesel, while a further “cracking” step is required to produce kerosene.  Microalgae can store energy as lipids and/or carbohydrates. However, for biofuels, microalgae with high TAG contents are required.  A number of such algae have been isolated, and lipid contents of up to 60% have been achieved.

According to Prof Grobbelaar, the challenge is large-scale, high-volume production, since it is easy to manipulate growth conditions in the laboratory for experimental purposes.  

The AUFWIND project (AUFWIND, a German term for up-current, or new impetus) in Germany consists of three different commercially-available photobioreactor types, which are being compared for lipid production.

Description: Lipid rich chlorella Tags: Lipid rich chlorella

Manipulated Chlorella with high lipid contents (yellow) in the Novagreen bioreactor

The photobioreactors each occupies 500 m2 of land surface area, are situated next to one another, and can be monitored continuously.  The three systems are from Novagreen, IGV, and Phytolutions.  The Novagreen photobioreactor is housed in a glass house, and consist of interconnected vertical plastic tubes roughly 150 mm in diameter. The Phytolutions system is outdoors, and consists of curtains of vertical plastic tubes with a diameter of about 90 mm.  The most ambitious photobioreactor is from IGV, and consists of horizontally-layered nets housed in a plastic growth hall, where the algae are sprayed over the nets, and allowed to grow while dripping from one net to the next.

Prof Grobbelaar’s main task was to manipulate growth conditions in such a way that the microalgae converted their stored energy into lipids, and to establish protocols to run the various photobioreactors. This was accomplished in just over two months of intensive experimentation, and included modifications to the designs of the photobioreactors, the microalgal strain selection, and the replacement of the nutrient broth with a so-called balanced one.

Prof Grobbelaar has no illusions regarding the economic feasibility of the project.  However, with continued research, optimisation, and utilisation of waste resources, it is highly likely that the first long-haul flights using microalgal-derived kerosene will be possible in the not-too-distant future.

Prof Grobbelaar from the Department of Plant Sciences, although partly retired, still serves on the editorial boards of several journals. He is also involved with the examining of PhDs, many of them from abroad.  In addition, he assisted the Technology Innovation Agency of South Africa in the formulation of an algae-biotechnology and training centre.  “The chances are good that such a centre will be established in Upington, in the Northern Cape,” Prof Grobbelaar said.

 

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