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11 February 2022 | Story Leonie Bolleurs and Nonsindiso Qwabe | Photo Supplied
The superpowers of women scientists at the UFS

The University of the Free State (UFS) has implemented several interventions to increase the diversity of its researchers, including its women scientists. Actions have paid off and resulted in an increase in the percentage of rated female researchers, from 27% in 2016 to 34% in 2021.


The university is also host to a number of science leaders in the six National Research Foundation (NRF)-funded South African Research Chairs Initiative (SARChI). Four of these research chairs are held by women. These are the research chairs in Vector-borne and Zoonotic Pathogens; Disease Resistance and Quality in Field Crops; Higher Education and Human Development; and Pathogenic Yeasts.

Health, medicine, and food sustainability are but three examples of areas in society where the women of the UFS is playing a critical role in science today.

In celebration of the International Day of Women and Girls in Science instituted by the United Nations General Assembly on 22 December 2015, the UFS is honouring its women scientists.

The science of science expos

One of the researchers at the UFS who is using science to make a difference in the lives of learners in our country, is Dr Angela Stott, Researcher and Teacher Educator in the Division of Social Responsibilities Projects (SRP) on the UFS South Campus. Together with colleagues in the SRP, she is involved in numerous Maths and Science outreach interventions to teachers and learners.

Science becomes fun for learners through the different initiatives created by Dr Stott and her colleagues. These include the online Learn Science programme (a brainchild of Dr Stott), using tablets donated by ioT.nxt, and the Creative Clubs intervention started by Dr Joleen Hamilton, a colleague of Dr Stott. In the latter, learners can take part in a MathArt competition and coding sessions.

In this year’s Creative Clubs projects, 100 Grade 9 learners from township schools will be mentored to prepare science fair projects for participation in the Expo for Young Scientists.

But why all this hard work for an expo? For these learners, the expo is more than just a public platform to showcase excellence. According to Dr Stott, learners in South African township schools tend not to be stimulated in extracurricular programmes, since teaching in these contexts is typically restricted to exam training.

However, her research has shown that higher-achieving learners from contexts of poverty respond well to such programmes and gain valuable knowledge, skills, and values from them. “This year, 100 higher-achieving Grade 9 learners from township schools will benefit from this programme, and next year another 100,” she says.

She adds that literature on this subject points to the need for structure, while also supporting learners’ development of autonomy when mentoring a learner to produce a science fair project. Dr Stott explains that the online programme around which this year’s intervention is built, has been created in a manner informed by literature on what is most likely to work. “By us researching the process, we will improve our understanding of how to maximise the benefits and mitigate the weaknesses that learners from poverty gain from such participation. This knowledge could help improve the effectiveness of such programmes throughout the country, and in other parts of the world where similar conditions apply,” she says.

Fighting for stronger immune systems

An international student from Zimbabwe, Nakai Matongera, a PhD graduate in Plant Breeding in the Department of Plant Sciences on the Bloemfontein Campus, is playing a key role in food sustainability in Africa with her research. She is a maize breeder working at the Scientific and Industrial Research and Development Centre (SIRDC) in Harare, Zimbabwe.

The focus of her PhD thesis is on the development of high-yielding and nutrient-dense maize varieties enriched with provitamin A, zinc, and essential amino acids such as lysine and tryptophan.

“With my research, I aimed to develop zinc-enhanced maize varieties that have great potential to reduce zinc deficiency in maize-based developing countries in sub-Saharan Africa,” she says.

Matongera explains that zinc-enhanced hybrids were developed by crossing introduced zinc donors and locally adapted maize inbred lines from three nutritional categories (normal, provitamin A, and quality protein maize (QPM). The hybrids were evaluated for both agronomic and nutritional performance under optimum drought and low nitrogen conditions.

“Results indicated that zinc-enhanced QPM hybrids accumulated high zinc under all growing conditions. However, the zinc-enhanced normal hybrids had the highest yield potential, implying dilution effects.”

“I find my research rewarding, because this biofortification strategy to combat micronutrient deficiency is cost-effective and has wide coverage and sustainability compared to other strategies such as clinical supplementation and food fortification,” says Matongera.

The outcomes of her research will one day, when it is implemented, change the lives of thousands of children in Africa who are suffering from zinc and iron deficiency. The shortage of zinc and iron in their diets affects their cognitive development as well as their immune systems, making them susceptible to a number of illnesses, including diarrhoea.

According to Prof Maryke Labuschagne, Nakai’s supervisor for her PhD study, this research will have a practical impact in Africa, as it will contribute towards the nutritional value of food.

Saving generations of humans and animals

When she could not pursue her childhood dream of becoming a vet, Dr Nthatisi Nyembe forged a new path in zoology, and today she is working in the Department of Zoology and Entomology on the UFS Qwaqwa Campus, where she focuses on veterinary parasitology.

Dr Nyembe’s research looks at the treatment and epidemiology of parasitic diseases in animals and humans, because – as she says – if animals are healthy, then humans are healthy. She says the ripple effect could save generations to come. “I want to be remembered for creating a drug that will make life easier for animals, because if animals are healthy, then the food we consume will also be healthy,” she says.

Dr Nyembe completed her studies on the Qwaqwa Campus from undergraduate to master’s level, specialising in Zoology. She was then awarded a scholarship to complete her PhD studies in Japan, where she spent four years looking into creating compounds that can treat and prevent unwanted parasites in animals, with a specific focus on mice.

“If I can get to a point where I can find one compound that has various benefits on multiple micro-organisms, then I will be happy”, she says.

While acknowledging the wide gender gap that still persists in her field of science, Nyembe says it should not hinder young girls who are interested in pursuing all levels of science.

“Society still looks down on girls and women, especially in Africa. If I go to a farmer as a woman and try to advise them about animal health, very few of them are receptive. However, the majority believe that I need to come with a man in order to be taken seriously. I just want to tell young aspiring female scientists that it is possible.”

“Whatever you put your mind to, you can pull through and achieve. Don’t allow yourself to be intimidated.”

News Archive

Higher than expected prevalence of dementia in South African urban black population
2010-09-22

 Prof. Malan Heyns and Mr Rikus van der Poel

Pilot research done by University of the Free State (UFS) indicates that the prevalence of dementia, of which Alzheimer’s disease is only one of the causes, is considerably higher than initially estimated. Clinical tests are now underway to confirm these preliminary findings.

To date it has been incorrectly assumed that dementia is less prevalent among urban black communities. This assumption is strongly disputed by the findings of the current study, which indicates a preliminary prevalence rate of approximately 6% for adults aged 65 years and older in this population group. Previous estimates for Southern Africa have been set at around 2,1%.

The research by the Unit for Professional Training and Services in the Behavioural Sciences (UNIBS) at the UFS and Alzheimer’s South Africa is part of the International 10/66 Dementia Research Group’s (10/66 DRG) initiative to establish the prevalence of dementia worldwide.

Mr Rikus van der Poel, coordinator of the local study, and Prof. Malan Heyns, Principal Investigator, say worldwide 66% of people with dementia live in low and middle income countries. It is expected that it will rise to more than 70% by 2040, and the socio-economic impact of dementia will increase accordingly within this period. 21 September marks World Alzheimer’s Day, and this year the focus is on the global economic impact of dementia. Currently, the world wide cost of dementia exceeds 1% of the total global GDP. If the global cost associated with dementia care was a company, it would be larger than Exxon-Mobil or Wal-Mart.

The researchers also say that of great concern is the fact that South Africa’s public healthcare system is essentially geared toward addressing primary healthcare needs, such as HIV/Aids and tuberculosis. The adult prevalence rate of HIV was 18,1% in 2007. According to UNAIDS figures more than 5,7 million people in South Africa are living with HIV/Aids, with an estimated annual mortality of 300 000. In many instances the deceased are young parents, with the result that the burden of childcare falls back on the elderly, and in many cases elderly grandparents suffering from dementia are left without children to take care of them. “These are but a few reasons that highlight the need for advocacy and awareness regarding dementia and care giving in a growing and increasingly urbanized population,” they say.

Low and middle income countries often lack epidemiological data to provide representative estimates of the regional prevalence of dementia. In general, epidemiological studies are challenging and expensive, especially in multi-cultural environments where the application of research protocols relies heavily on accurate language translations and successfully negotiated community access. Despite these challenges, the local researchers are keen to support advocacy and have joined the international effort to establish the prevalence of dementia through the 10/66 DRG.

The 10/66 DRG is a collective of researchers carrying out population-based research into dementia, non-communicable diseases and ageing in low and middle income countries. 10/66 refers to the two-thirds (66%) of people with dementia living in low and middle income countries, and the 10% or less of population-based research that has been carried out in those regions.

Since its inception in 1998, the 10/66 DRG has conducted population based surveys in 14 catchment areas in ten low and middle income countries, with a specific focus on the prevalence and impact of dementia. South Africa is one of seven LAMICs (low and medium income countries) where new studies have been conducted recently, the others being Puerto Rico, Peru, Mexico, Argentina, China and India.

Mr Van der Poel says participating researchers endeavour to conduct cross-sectional, comprehensive, one-phase surveys of all residents aged 65 and older within a geographically defined area. All centres share the same core minimum dataset with cross-culturally validated assessments (dementia diagnosis and subtypes, mental disorders, physical health, anthropometry, demographics, extensive non-communicable risk factor questionnaires, disability/functioning, health service utilization and caregiver strain).

The local pilot study, funded by Alzheimer’s South Africa, was rolled out through an existing community partnership, the Mangaung University of the Free State Community Partnership Programme (MUCPP).

According to Mr Van der Poel and Prof. Heyns, valuable insights have been gained into the myriad factors at play in establishing an epidemiological research project. The local community has responded positively and the pilot phase in and of itself has managed to promote awareness of the condition. The study has also managed to identify traditional and culture-specific views of dementia and dementia care. In addition, existing community-based networks are being strengthened, since part of the protocol will include the training and development of family caregivers within the local community in Mangaung.

“Like most developing economies, the South African population will experience continued urbanization during the next two decades, along with increased life expectancy. Community-based and residential care facilities for dementia are few and far between and government spending will in all probability continue to address the high demands associated with primary healthcare needs. These are only some of the reasons why epidemiological and related research is an important tool for assisting lobbyists, advocates and policymakers in promoting better care for those affected by dementia.”

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za  
21 September 2010

 

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