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15 February 2022 | Story Andrè Damons
Dr Jeanette Mmabosa Sebaeng
After graduating with her post-basic diploma in Forensic Nursing from the University of the Free State (UFS) in 2006, Dr Jeanette Mmabosa Sebaeng returned to the institution as its newly appointed Head of the School of Nursing.

Dr Jeanette Mmabosa Sebaeng, newly appointed Head of the School of Nursing at the University of the Free State (UFS), is a UFS alumna who believes that the skills and knowledge she has learned here and at other institutions where she has worked, would contribute towards the vision of the university. Dr Sebaeng assumed her new position in January 2022 and is  looking forward to working with Prof Gert van Zyl, Dean of the Faculty of Health Sciences, and the rest of the team in the school and the faculty.

Joining Kovsies

“I am so thrilled; some of the expected roles of this position include serving in some university management structures beyond the school and external stakeholders, and I look forward to the exposure and profound experiences I will receive in this institution,” says Dr Sebaeng. According to her, the decision to join Kovsies emanated from her envisaged personal and professional growth, mainly in the sphere of management and leadership in the nursing profession as well as in the university. “The organisational culture of ubuntu embedded in the UFS learning and teaching strategy resonates well with the saying in my culture: ‘Motho ke motho ka batho ba bangwe’ (I am because you are). The ubuntu principles of respect, caring, compassion, and dignity of others are in alignment with my personal values, and this in itself is an assurance that I will fit snuggly and thrive in the Kovsie environment.”

The University of the Free State’s vision of producing students who are professionally competent and globally employable, seems to be attainable. During my first two weeks in office, I received documents from Dubai, Philadelphia, and London for academic verification of our graduates who applied for job opportunities in these countries. This is fascinating, and I wish there could be a way of getting feedback from employers in these and other countries to determine if we are producing graduates with the desired attributes that are internationally comparable,” says Dr Sebaeng.

Looking forward

“The world of nursing education in the country is very small and there is a lot of interaction among members from different universities. I learned on one platform that the UFS School of Nursing has a state-of-the-art simulation laboratory rated number one and the best in the country and perhaps even in Southern Africa. I cannot wait to engage with both the staff and students about the use of the simulation laboratory; I would like to ensure its optimal use, while maintaining it for the benefit of the students.”

Visions and goals

As Head of the school, Dr Sebaeng hopes to provide leadership, guidance, and support to staff and students in the School of Nursing, and to ensure that the environment is warm and conducive to all. She is also looking forward to working harmoniously with the staff within the school, as she believes in an environment that enables all staff members to flourish in the expected academic activities.  “I will also ensure that I work according to the acceptable and recommended norms and standards of the nursing profession, which will be to the benefit of the School of Nursing and the nursing practice. For instance, good relations with the relevant stakeholders such as the FSDoH, clinical health facilities, and the South African Nursing Council, among others, remain crucial for the education and training of nursing students. All members’ views and inputs leading to the upscaling of the school will be valued,” states Dr Sebaeng.

Dr Sebaeng, who previously worked as a lecturer and researcher at the North-West University (NWU), says there is a vast difference between her current position and the previous one. According to her, her current position brings more responsibilities, including leading, guiding, and making decisions that should yield tangible, set goals aligned with the vision of the university.

A mother of two and grandmother of a handsome two-year-old grandson, Dr Sebaeng is adventurous and loves travelling outside the country, with an outgoing personality to match. Cooking and trying out new dishes with her family is also very satisfying. She also loves interacting with young children, which led her to teaching Sunday school for 30 years. “My life mainly revolves around church, home, and work,” says Dr Sebaeng.

The impact of COVID-19 on nurses

Nursing education teaches nurses to be competent, knowledgeable, and to acquire relevant skills that enable them to assume their professional role with confidence. However, nurses also require optimal health to provide quality care to our societies. “The outbreak of COVID-19 has taught us that nursing in South Africa lacks systems aimed at developing resilience and coping mechanisms during pandemics. Most nurses were and still are scared that they may contract the virus and infect their own families, or even worse, die themselves. Nursing education institutions must include workable psychological interventions in the teaching of student nurses, which will assist nurses to survive during future pandemics. Despite this, clinical practices must try to alleviate compassion fatigue, work-related stress, and burnout experienced by nurses, in order to render optimal health care and to continue to be functional in their daily activities.”

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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