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11 July 2022 | Story Valentino Ndaba | Photo Pexels
Dr Maramura
Dr Tafadzwa Maramura says she carved her path by remaining focused and resolute on her journey.

The African proverb ‘it takes a village to raise a child’ conveys the message that it requires many people to provide a safe and healthy environment for children. The village gives the child the security needed to develop and be able to realise their hopes and dreams. 

Dr Tafadzwa Maramura believes that the same applies vice versa. “It takes a good child to be raised by a village. You need to understand that the village can only do so much, the rest lies on your shoulders as the child,” she says.

The journey of a child raised by a village
The senior lecturer reflects on the journey that led her to serve in the Department of Public Administration and Management at the University of the Free State. At the age of three, she lost her father, who was an army general in Zimbabwe. Soon after, her academic journey would begin at a boarding school. Her widowed mother then moved her to a mission school due to financial constraints, seeing that she had two more children relying on her for survival. Since her father served in the government, she qualified for a state scholarship, which saw her launch her academic career in South Africa as an undergraduate student. 

“I came to South Africa in 2010 and pursued a Bachelor of Social Science degree in Development Economics at the University of Fort Hare. Once my honours were conferred, I acquired my master’s within a year. Thereafter, I enrolled at the North-West University, where I completed my PhD within two years.”

Dr Maramura was the Vice-Chancellor’s valedictorian for her bachelor, honours, and 
master’s degrees. Graduating cum laude was another way of ensuring that she pays it forward to the village that raised her. Not only was she funded by the Zimbabwean government, but she also received financial aid from South Africa throughout her studies. 

Once a child, now part of the village 
Today, as founder of a foundation based in Zimbabwe, she pays the fees of orphaned and disadvantaged primary school learners. “I wish everyone could adopt a child, pay their fees, buy their schoolbooks – because we only have each other, we do not have anyone else. That’s also part of what I call co-creating.”

The Brightest Young Minds in Africa alumna goes above and beyond focusing on academics, as she believes that “if you are the only one holding the light, everyone else will have to follow behind you to make sure that they can see ahead. However, if you share that light, then it means many more can see, therefore making it easier to solve societal challenges as a collective”.

She argues that the amount of money you spend on lunch could pay a child’s school fees for a term, and the cash that you use to buy a jacket or a pair of shoes, could cover a child’s fees for a month.
Making a difference in the lives of young children is her way of playing the role of the village now that she is an adult. “I make sure that wherever I am, I make an impact in the lives of others.”

Dr Maramura says she plans to make sure that life is better for the next young African female, by setting up a mentorship programme for the next generation of leaders. In addition to that, her goal is to become an associate professor, rise in academic rank, and develop a research unit that can speak to issues of sustainable service delivery.

On how to be a good child 
You do not need to be a figure of authority to make an impact. According to Dr Maramura, all you need is a desire to co-create, and making sure that the public is in a different place after you have left the relevant office you hold or the organisation you serve. “Make sure that you can co-exist, because humans don’t live in a vacuum, we exist among each other.”

Serving the people makes all the difference. She suggests that everyone asks themselves what they are doing for their community, class, or family. 

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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