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24 June 2022 | Story Dr Nitha Ramnath
Ghana

“We are trying to close the divide between Ghanaian and South African higher education institutions. Many Ghanaians look to UK and US universities as their first option. However, the same level of education, at a far less rate, is offered at South African higher education institutions – and the University of the Free State in particular.”

These were some of the sentiments shared by His Excellency Mr Charles Asuako Owiredu, High Commissioner of the Republic of Ghana to South Africa, during his recent visit to the University of the Free State.

The High Commissioner, accompanied by the Deputy High Commissioner and Head of Protocol, was hosted by Prof Francis Petersen. After a successful meeting, the students and academics from the Ghanaian community were also engaged. “The Vice-Chancellor was full of praise for the Ghanaian students and their performance at the UFS,” said the High Commissioner.

Prof Chitja Twala, Vice-Dean in the Faculty of the Humanities, highlighted the longstanding relationship that the UFS has with the University of Ghana. “We have a good relationship with the Department of History at the University of Ghana, and we are looking forward to collaboration with the institution,” added Prof Twala.

The High Commissioner felt strongly about cementing the relationships that already exist between the UFS and universities in Ghana and will lobby for education to be included in the master framework used as an operational document between the two countries. Faculty exchanges between the UFS and Ghanaian universities were also encouraged by the High Commissioner.

The High Commissioner encouraged Ghanaian students and academics at the UFS to suggest ways to deepen the relationship between the UFS and Ghanaian institutions.

Dr Prince Sarpong, Senior Lecturer in the School for Financial Planning Law at the UFS, proposed a collaboration between the UFS and Ghanaian institutions in the field of financial planning, whereby there could be an opportunity to reach out and expand the practice of financial planning to institutions in Ghana. The High Commissioner was eager to know more about financial planning and its location within law.

Ghanaian students who attended the meeting shared their experiences and perspectives about the UFS and indicated that an excellent relationship exists with project supervisors while pursuing their studies remotely.

According to Ghanaian students based on the UFS campuses, the UFS is doing great work by engaging students from Ghana in the UFS programme. However, students indicated that challenges were experienced with the South African Qualifications Authority (SAQA).

Dr Cornelius Hagenmeier, Director of the Office for International Affairs at the UFS, assured students that the aspect of SAQA is important and will be looked into, as it relates to the recruitment of students.

The High Commissioner also suggested that the Ghana Accreditation Board engage with SAQA.

 A UFS delegation will be visiting Ghana in October to explore the opportunities in agriculture, entrepreneurship, and the Business School.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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