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30 March 2022 | Story Bulelwa Moikwatlhai | Photo Supplied
International office
An international celebration. The Office for International Affairs hosted more than a hundred local and international students at the 2022 ‘Welcome to Mzansi’ event, integrating international students to life at the UFS.

On 18 March 2022, the Internationalisation at Home (I@H) portfolio in the Office for International Affairs at the University of the Free State (UFS) hosted its annual first-year international student welcome function themed ‘Welcome to Mzansi’ at the RAG farm. The function hosted more than one hundred local and international students who are part of the I@H integration initiative – the Umoja Buddy Programme. UFS students from the Arts and Culture division in Student Affairs set the tone for the evening with a drama presentation articulating a student’s first day in the UFS community, in Bloemfontein, and its surroundings. The drama showcased the diverse student community represented at the UFS.

A welcome video from the Rector and Vice-Chancellor of the university, Prof Francis Petersen, was shared with the students, highlighting how the past two years of the pandemic have equipped the students with key skills that they will use in the future. “I believe that the lessons you have learned will help you in the future, I know you will make an impact in your field. As a residential university, we welcome our students and staff back on campus in 2022 to learn, work, and socialise in a way that minimises risk but still provides our students with an on-campus student life.”

Prof Mudzi, the Director of the Postgraduate School, advocated the importance of furthering one’s studies. He stated, “You need to start working hard from day one of university education; the marks you get during your undergraduate years have a huge bearing on your future and your ability to progress to postgraduate studies, as it is highly dependent on the average mark you get at undergraduate level.” In his concluding remarks, Prof Mudzi advised the students to, “learn something new, engage with new people and cultures, enjoy South Africa, while succeeding in your studies at the UFS and working hard”.

Dr Hagenmeier, Director of the Office for International Affairs, delivered the keynote welcome address for the international students, with a brief introduction to the OIA staff. This, as outlined in his address, served the purpose of ensuring that students are familiar with the channels of communication, representatives, and office-bearers in specific portfolios under the OIA, as well as the functions of the OIA.

The evening ended off with musical performances by UFS students, while the attendees dined and networked over a hot plate of food. In the same spirit, the dance floor was opened. This was a very important part of integration, uniting the students regardless of their nationality, race, gender, etc. The students did not think twice about taking to the dance floor – seeing everyone dance made students who did not participate afraid that they were missing out.   


News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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