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National multiplication training on internationalisation in South Africa

09 March 2022 | Story Dr Cornelius Hagenmeier

The University of Venda (Univen) and the University of the Free State (UFS) have been awarded a grant from the German Academic Exchange Service (DAAD) Dialogue on Innovative Higher Education Strategies (DIES) National Multiplication Trainings (NMT) programme to implement training on internationalisation for higher education leaders and managers. It is co-funded by the German Rectors’ Conference (HRK) and the two coordinating universities. Two emerging internationalisation managers, Mr Matome Mokoena (UFS) and Mrs Nontlanhla Ntakana (Univen), are coordinating the programme, which is supported by DAAD with 25 000 euros.

Dr Segun Obadire (Univen) and Dr Cornelius Hagenmeier (UFS), who serve as directors responsible for the international offices at their universities, are part of the training committee. The theme of the training programme is ‘Enabling Internationalisation in Light of the 2020 Policy Framework for Internationalisation of Higher Education in South Africa 2022’; it comprises two training workshops and several virtual engagements. The first training workshop was held at the UFS from 1 to 3 March 2022.

Trendsetters

Mrs Nontlanhla Ntakana and Mr Matome Mokoena are alumni of the biannual DAAD DIES Training Course on Management of Internationalisation (MOI) at the Leibniz University Hannover in Germany. They seized the opportunity to forge a multiplication training that would impact internationalisation leaders and managers from across South Africa and empower them to leverage the 2020 Policy Framework for Internationalisation of Higher Education in South Africa to advance the internationalisation process at their institutions.

Internationalisation experts

Dr Nico Jooste and Mrs Merle Hodges served as external experts on the training committee. Both are internationally renowned experts in the field and former presidents of the International Education Association of South Africa (IEASA). Mr Leolyn Jackson (Central University of Technology, CUT) and Prof Lynette Jacobs (UFS) also contributed to the first training workshop.

Structure

This programme commenced in February, with participants engaging in topical readings and submitting their first assignment. First, a virtual workshop introduced participants to the UNIVEN Moodle e-learning platform used for the course. The face-to-face workshop at the UFS will be followed by a second in-person training at the University of Venda in September 2022. Virtual workshops and support of the participants through a dedicated WhatsApp group and other mentorship programmes will ensure the continuity of the training between the face-to-face workshops. Participants who were unable to attend the UFS and UNIVEN workshops in person could participate via a virtual link, thus ensuring that no participant is left behind.

Participants

Twenty participants from eight public higher education institutions were selected by the training committee to participate in the training programme. Two participants from this year’s NMT cohort were also accepted into the DIES MOI course at the Leibniz University Hannover in Germany. They are Prof Nontokozo Mashiya from the University of Zululand (Unizulu) and Mbali Mkhize from the Mangosuthu University of Technology (MUT). Participants in the first workshop have indicated that they gained a lot from the numerous exercises and activities in the programme. They also mentioned that the programme would change the outlook of internationalisation at their universities in the future.

News Archive

UFS study on cell development in top international science journal

2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.

Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za
18 September 2008

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