Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
25 March 2022 | Story Leonie Bolleurs | Photo Charl Devenish
Prof Liezel Herselman Inuagural Lecture
At the inaugural lecture were from the left: Prof Danie Vermeulen, Dean of the Faculty of Natural and Agricultural Sciences, Prof Liezel Herselman, Dr Adré Minnaar-Ontong, Senior Lecturer in the Department of Plant Sciences and Subject Head of Plant Breeding, and Dr Molapo Qhobela, Vice-Rector: Institutional Change, Strategic Partnerships and Societal Impact.

Prof Liezel Herselman, Academic Head of the Department of Plant Sciences at the University of the Free State (UFS),) delivered her inaugural lecture on the Bloemfontein Campus this week (24 March 2022). The theme of the lecture was the ongoing battle against destructive cereal killers. 

With 28 years of extensive experience as a researcher, her work focuses on marker-assisted disease resistance breeding in wheat within a South African context. When she joined the UFS in 2004, Prof Herselman decided to apply her research expertise in marker-assisted breeding to the problems faced by wheat producers in the Free State and Northern Cape. The Free State is one of the major dryland wheat production areas in South Africa, while irrigation wheat is produced along the major rivers in the Northern Cape. 

Protection against fungal diseases

Concentrating specifically on Fusarium head blight (or wheat scab) and three rust diseases – leaf rust, stem rust, and stripe rust – she has done work to provide wheat plants with ‘tools’ to protect themselves against these fungal diseases.

According to Prof Herselman, there are many genes available in different wheat genotypes and related grass species that provide excellent protection against various races of these diseases. “Some of these genes provide protection or resistance from the seedling stage, while others provide resistance at the adult plant stage. We are thus aiming to combine as many of these genes as possible into a single wheat cultivar, without compromising yield and bread-making quality.”

She says the genes are combined by making crosses between resistant and susceptible cultivars or lines. Conventionally, through a time-consuming process, the incorporation of these genes is tested in the greenhouse and field by infecting plants with the disease to see which plants are resistant and which are not.

They can, however, follow the transfer of these genes to newly developed lines by applying molecular markers. Prof Herselman explains: “A molecular marker is a genomic fragment linked to the gene, which we can follow in the offspring we create from the crosses using different DNA techniques in the laboratory. This enables us to select new wheat lines that contain the highest number of resistance genes. The identified best lines are then used in further crosses and/or released as pre-breeding lines to commercial wheat breeding companies.”

Impact on food security

Her research has an impact on society by providing food security to both commercial and small-scale producers, as well as the end users of wheat (people buying bread and other wheat products). As researcher, it is also important for her to send out students to the workplace who can continue with this task in future.

Prof Herselman believes that when cultivars with fungal-disease tolerance or resistance are released and used by producers, it not only reduces the cost of spraying against diseases, but also increases yields by protecting the crop against fungal diseases. “We live in a world where the population is increasing daily, but land available for agriculture is not increasing and some areas are even lost due to urban development. Increasing yield in available production areas will thus have a positive impact on food security,” she says.

Besides contributing to the country’s food security, she takes pleasure in every aspect of her work. Although she misses the hands-on part of the work as academic head of the department and getting her hands dirty, she still enjoys managing the different research projects (from the conceptualisation phase to data analysis and publishing of results). The part she loves the most is to see the growth in her postgraduate students – from the moment they enter the laboratory for the first time until the day they walk out of the laboratory with their degrees. 

“It adds purpose to my life knowing that I have made a difference in a student’s life and equipped him or her with the necessary tools to be successful in the marketplace. Being able to share your knowledge is a gift, but with that gift comes a lot of responsibility as well. I am, however, up for the challenge,” concludes Prof Herselman. 

News Archive

New world-class Chemistry facilities at UFS
2011-11-22

 

A world-class research centre was introduced on Friday 18 November 2011 when the new Chemistry building on the Bloemfontein Campus of the University of the Free State (UFS) was officially opened.
The upgrading of the building, which has taken place over a period of five years, is the UFS’s largest single financial investment in a long time. The building itself has been renovated at a cost of R60 million and, together with the new equipment acquired, the total investment exceeds R110 million. The university has provided the major part of this, with valuable contributions from Sasol and the South African Research Foundation (NRF), which each contributed more than R20 million for different facets and projects.
The senior management of Sasol, NECSA (The South African Nuclear Energy Corporation), PETLabs Pharmaceuticals, and visitors from Sweden attended the opening.

Prof. Andreas Roodt, Head of the Department of Chemistry, states the department’s specialist research areas includes X-ray crystallography, electrochemistry, synthesis of new molecules, the development of new methods to determine rare elements, water purification, as well as the measurement of energy and temperatures responsible for phase changes in molecules, the development of agents to detect cancer and other defects in the body, and many more.

“We have top expertise in various fields, with some of the best equipment and currently competing with the best laboratories in the world. We have collaborative agreements with more than twenty national and international chemistry research groups of note.

“Currently we are providing inputs about technical aspects of the acid mine water in Johannesburg and vicinity, as well as the fracking in the Karoo in order to release shale gas.”

New equipment installed during the upgrading action comprises:

  • X-ray diffractometers (R5 million) for crystal research. Crystals with unknown compounds are researched on an X-ray diffractometer, which determines the distances in angstroms (1 angstrom is a ten-billionth of a metre) and corners between atoms, as well as the arrangement of the atoms in the crystal, and the precise composition of the molecules in the crystal.
  • Differential scanning calorimeter (DSC) for thermographic analyses (R4 million). Heat transfer and the accompanying changes, as in volcanoes, and catalytic reactions for new motor petrol are researched. Temperature changes, coupled with the phase switchover of fluid crystals (liquid crystals -watches, TV screens) of solid matter to fluids, are measured.
  • Nuclear-magnetic resonance (NMR: Bruker 600 MHz; R12 million, one of the most advanced systems in Africa). A NMR apparatus is closely linked with the apparatus for magnetic resonance imaging, which is commonly used in hospitals. NMR is also used to determine the structure of unknown compounds, as well as the purity of the sample. Important structural characteristics of molecules can also be identified, which is extremely important if this molecule is to be used as medication, as well as to predict any possible side effects of it.
  • High-performance Computing Centre (HPC, R5 million). The UFS’ HPC consists of approximately 900 computer cores (equal to 900 ordinary personal computers) encapsulated in one compact system handling calculations at a billion-datapoint level It is used to calculate the geometry and spatial arrangements, energy and characteristics of molecules. The bigger the molecule that is worked with, the more powerful the computers must be doing the calculations. Computing chemistry is particularly useful to calculate molecular characteristics in the absence of X-ray crystallographic or other structural information. Some reactions are so quick that the intermediary products cannot be characterised and computing chemistry is of invaluable value in that case.
  • Catalytic and high-pressure equipment (R6 million; some of the most advanced equipment in the world). The pressures reached (in comparison with those in car tyres) are in gases (100 times bigger) and in fluids (1 500 times) in order to study very special reactions. The research is undertaken, some of which are in collaboration with Sasol, to develop new petrol and petrol additives and add value to local chemicals.
  • Reaction speed equipment (Kinetics: R5 million; some of the most advanced equipment in the world). The tempo and reactions can be studied in the ultraviolet, visible and infrared area at millisecond level; if combined with the NMR, up to a microsecond level (one millionth of a second.

Typical reactions are, for example, the human respiratory system, the absorption of agents in the brain, decomposition of nanomaterials and protein, acid and basis polymerisation reactions (shaping of water-bottle plastic) and many more.

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept