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The impact of cereal killers on food security

25 March 2022 | Story Leonie Bolleurs | Photo Charl Devenish

Prof Liezel Herselman Inuagural Lecture — At the inaugural lecture were from the left: Prof Danie Vermeulen, Dean of the Faculty of Natural and Agricultural Sciences, Prof Liezel Herselman, Dr Adré Minnaar-Ontong, Senior Lecturer in the Department of Plant Sciences and Subject Head of Plant Breeding, and Dr Molapo Qhobela, Vice-Rector: Institutional Change, Strategic Partnerships and Societal Impact.

Prof Liezel Herselman, Academic Head of the Department of Plant Sciences at the University of the Free State (UFS),) delivered her inaugural lecture on the Bloemfontein Campus this week (24 March 2022). The theme of the lecture was the ongoing battle against destructive cereal killers.

With 28 years of extensive experience as a researcher, her work focuses on marker-assisted disease resistance breeding in wheat within a South African context. When she joined the UFS in 2004, Prof Herselman decided to apply her research expertise in marker-assisted breeding to the problems faced by wheat producers in the Free State and Northern Cape. The Free State is one of the major dryland wheat production areas in South Africa, while irrigation wheat is produced along the major rivers in the Northern Cape.

Protection against fungal diseases

Concentrating specifically on Fusarium head blight (or wheat scab) and three rust diseases – leaf rust, stem rust, and stripe rust – she has done work to provide wheat plants with ‘tools’ to protect themselves against these fungal diseases.

According to Prof Herselman, there are many genes available in different wheat genotypes and related grass species that provide excellent protection against various races of these diseases. “Some of these genes provide protection or resistance from the seedling stage, while others provide resistance at the adult plant stage. We are thus aiming to combine as many of these genes as possible into a single wheat cultivar, without compromising yield and bread-making quality.”

She says the genes are combined by making crosses between resistant and susceptible cultivars or lines. Conventionally, through a time-consuming process, the incorporation of these genes is tested in the greenhouse and field by infecting plants with the disease to see which plants are resistant and which are not.

They can, however, follow the transfer of these genes to newly developed lines by applying molecular markers. Prof Herselman explains: “A molecular marker is a genomic fragment linked to the gene, which we can follow in the offspring we create from the crosses using different DNA techniques in the laboratory. This enables us to select new wheat lines that contain the highest number of resistance genes. The identified best lines are then used in further crosses and/or released as pre-breeding lines to commercial wheat breeding companies.”

Impact on food security

Her research has an impact on society by providing food security to both commercial and small-scale producers, as well as the end users of wheat (people buying bread and other wheat products). As researcher, it is also important for her to send out students to the workplace who can continue with this task in future.

Prof Herselman believes that when cultivars with fungal-disease tolerance or resistance are released and used by producers, it not only reduces the cost of spraying against diseases, but also increases yields by protecting the crop against fungal diseases. “We live in a world where the population is increasing daily, but land available for agriculture is not increasing and some areas are even lost due to urban development. Increasing yield in available production areas will thus have a positive impact on food security,” she says.

Besides contributing to the country’s food security, she takes pleasure in every aspect of her work. Although she misses the hands-on part of the work as academic head of the department and getting her hands dirty, she still enjoys managing the different research projects (from the conceptualisation phase to data analysis and publishing of results). The part she loves the most is to see the growth in her postgraduate students – from the moment they enter the laboratory for the first time until the day they walk out of the laboratory with their degrees.

“It adds purpose to my life knowing that I have made a difference in a student’s life and equipped him or her with the necessary tools to be successful in the marketplace. Being able to share your knowledge is a gift, but with that gift comes a lot of responsibility as well. I am, however, up for the challenge,” concludes Prof Herselman.

News Archive

UFS receives R13,7 Million for Research into Prehistoric Organisms

2007-03-27

Some of the guests attending the launch of the research contract are: Dr Siyabulela Ntutela (Deputy Director: Biotechnology at the Department of Science and Technology), Dr Godfrey Netswera (Manager of Thuthuka and the Support Programme at the National Research Foundation (NRF)), Dr Esta van Heerden (Platform Manager and lecturer at the Department of Microbial, Biochemical and Food Biotechnology at the UFS), Mr Butana Mboniswa (Chief Executive Officer of BioPAD), and Mr Vuyisele Phehani (Portfolio Manager for BioPAD).
Photo: Leonie Bolleurs

The University of the Free State (UFS) has been awarded a massive R13,7 million contract to conduct research into prehistoric micro-organisms which live under extreme conditions, for example in mineshafts.

This is one of the biggest research contracts awarded to the UFS in recent years.

The biotechnology research contract was awarded to the UFS by BioPAD, a South African biotechnology company that brokers partnerships between researchers, entrepreneurs, business, government and other stakeholders to promote innovation and create sustainable biotechnology businesses.

The project is endorsed by the Department of Science and Technology and the National Research Foundation (NRF), which contributes to the bursaries of the 17 postgraduate students on the programme.

The contract involves the establishment of a Platform for Metagenomics - a technique which allows researchers to extract the DNA from microbes in their natural environment and investigate it in a laboratory.

“Through this platform we will be able to understand deepmine microbial populations
and their potential application in the search for life in outer space. It is most likely
that, if life were to be found on other planets in our solar system, it would probably
resemble that which existed millions of years ago on earth. Apart from all this, these
organisms have unique properties one can exploit in biotechnological application for
South Africa and its community,” said Dr Esta van Heerden, platform manager and
lecturer at the UFS Department of Microbial, Biochemical and Food Biotechnology.
She is assisted by her collegues, Prof. Derek Litthauer and Dr Lizelle Piater.

“The platform aims to tap into the unique genetic material in South African mines
which will lead to the discovery of new genes and their products. These new and unique products will find application in the medical field (anti-cancer, anti-bacterial en anti-viral cures), the industrial sector (nanotechnology, commercial washing agents and the food industry), environmental sector (pollution management, demolition of harmful metals and other toxic waste),” said Dr Van Heerden.

According to Dr Van Heerden, the Metagenomics Platforms stems from the Life in
Extreme Environments (LExEN) programme which was started in 1994 by Princeton
University in the United States of America (USA) in South African mines with grants
from among others the National Aeronautics and Space Administration (NASA) and
the National Science Foundation (NSF) in the USA. Other international collaborators
on the project include Geosynec Consultants Inc. (USA), Oak Ridge National
Laboratory (USA), the University of Tennessee (USA) and in South Africa the
Universities of the Witwatersrand, North West and Limpopo and companies like BHP
Billiton, MINTEK and mining companies like Harmony, Gold Fields and AngloGold
Ashanti.

The research field laboratory of the Metagenomics Platform, which was situated in
Glen Harvey, was moved to the Main Campus of the UFS in Bloemfontein. “In this
way the university has become the central hub for all research programmes. We are
also the liaison between the LExEN programme and the various mining companies
involved,” said Dr Van Heerden. The new laboratory was introduced during the
launch of the research contract.

“Our decision to commit BioPAD to this project stems from the company’s commitment to advance human capacity development to strengthen South Africa’s research infrastructure. It is also part of our aim to create and protect intellectual property,” said Mr Butana Mboniswa, Chief Executive Officer of BioPAD.

Talking on behalf of the UFS senior management, Prof. Teuns Verschoor, Vice-Rector
of Academic Operations, said that the university shares the excitement to be part of
the exploration of unknown forms of life, the discovery of new genes and
their products and in applying newly gained knowledge to better understand our
universe.

Media release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl@ufs.ac.za
27 March 2007

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