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25 March 2022 | Story Anthony Mthembu | Photo Supplied
Bloemfontein Campus Choir
The Bloemfontein Campus Choir singing in front of the Main Building for students in celebration of Human Rights Day.

Students on the Bloemfontein Campus were treated to a lunch-hour music performance by the campus choir – an uplifting musical production led by the indomitable Sibongile Mngoma, conductor of the choir on the Bloemfontein Campus. The performance, which was in celebration of Human Rights Day, took place on 22 March 2022 in front of the Main Building.  “We realised that people were hungry to hear beautiful music and beautiful sounds, and we started these pop-up performances just to revive people’s spirit and to give them hope,” says Lucy Sehloho, Officer: Arts and Culture in the Department of Student Affairs. As such, the staff and students at the University of the Free State (UFS) can look forward to a series of pop-up performances by the UFS choirs, specifically on the Bloemfontein and South Campuses.

One institution, different sounds

According to Sehloho, “the choirs are all running on the same constitution and the same code of conduct”. However, they are slightly different in sound, and this is determined by the audience to whom the respective choirs cater, and the number of members involved in the choir. The Bloemfontein Campus choir is known to cover genres such as rap, trap, classical music, and South African choral music. However, the Qwaqwa Campus choir focuses on choral music and various African sounds, while the South Campus choir manoeuvres through most of the abovementioned genres.

Preparing for life as an artist after university 

It is important to note that the choirs are not just a safe space that encourages expression for young artists. Indeed, for many students it is also the beginning of a career. As such, they are taught lessons about financial literacy and the ability to brand themselves as artists. “One of the things I am teaching the students is how to price and cost themselves,” Sehloho highlighted. In fact, Sehloho argues that a major challenge among young performers when they leave university, is that – because they have never charged a fee for their service – they have no idea how to price and sustain themselves from the money they acquire. Consequently, industry experts are invited to provide insight into the realities of the world for artists once they start working. These industry experts include Dr Jerry Mofokeng wa Makhetha.

Future endeavours for the respective choirs

In addition to these lessons, the choirs have various projects that they are working on. The Bloemfontein Campus choir is currently planning performances for national holidays such as Freedom Day and Youth Day. The choir is also gearing up for a performance of Handel’s Messiah in celebration of Easter. The South Campus is specifically working towards the Network Festival in collaboration with Oranje Girls’ School. Furthermore, the Bloemfontein Campus choir will compete in the Sing for Gold competition in Barcelona this coming October. Once an institutional choir has been finalised, the Arts and Culture team will represent the UFS and the nation at the World Choir Games in 2023.

The main challenge experienced by the choirs

Although the choirs are succeeding in entertaining and uplifting the UFS community, there are still some challenges that hinder their growth to some extent. Racial diversity is one of these barriers. ‘’When someone looks at the choir, they don’t get to see the full picture of who we as the University of the Free State are in terms of diversity,’’ she explains. Therefore, Sehloho notes that the respective choirs are open to students from all walks of life in order to ensure racial and cultural diversity. As such, students who are interested in joining can contact Lucy Sehloho at  SehlohoLP@ufs.ac.za

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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