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18 May 2022 | Story Rulanzen Martin | Photo Supplied
Jon Kehrer
Jon Kehrer is a prolific academic and scholar. He also spent a few years teaching English in the Middle East.

It was a former professor who influenced American scholar Jon Kehrer to further his academic journey with the Department of Hebrew at the University of the Free State (UFS). And it was at the UFS where he recently graduated cum laude with a master’s degree in Hebrew, and was named recipient of the Dean’s Medal. 

Although he never expected to receive the Dean’s Medal, he is very glad – and somewhat relieved – that his dissertation made it through the examiners. “I never anticipated receiving this award. It makes me even more grateful for the strong Hebrew Department at UFS, and their rigorous standards for their students,” Kehrer says. 

“I wish I had been able to attend the graduation ceremony, but the circumstances of the semester just did not allow it.” Kehrer is currently teaching in the areas of the Old Testament and Biblical Languages at the Ozark Christian College (OCC) in Missouri, USA. In addition to his UFS qualifications Kehrer also holds a Bachelor of Theology qualification from the OCC. “I love the opportunity to invest in students and help them see new perspectives,” he says. 

UFS Hebrew a firm foundation for a solid academic career  

“I was looking for a high-quality and challenging programme that was flexible, especially since I work full-time and have a large family,” Kehrer says, as he recalls how he initially decided to become part of the UFS. He remembers fondly how Dr Kevin Chau, senior lecturer in Hebrew at the UFS, motivated and supported him when he first enrolled for the BA Honours programme. 

It is also a testament that the Department of Hebrew has made an impact internationally for the quality of its academic offerings. “Dr Chau helped me to think about how what I was learning would have an impact on my research and teaching in the future, and he was always quick to provide thorough and constructive feedback on my work,” Kehrer says.  

Once enrolled for the master’s programme it was initially difficult to know which direction to pursue and what topic to research, but the guidance and support of his two advisors, Prof Cynthia Miller-Naude and Prof Jacobus Naude, was “very helpful”.

“They never dictated what paths I should pursue, but they listened carefully and provided expert guidance to help me choose the path that would best suit my interests and the needs of the field,” he says. 

It was this support from the Department of Hebrew and its excellent reputation that came full circle when Kehrer was named Dean’s Medal recipient for achieving the highest marks of any student in a master’s qualification in the UFS Faculty of The Humanities. 

Dissertation a closer look at verbs in Biblical Hebrew 

His dissertation focused on Biblical Hebrew and how the object of a verb appears in various ways. “Sometimes an object appears by itself, but sometimes it can have a preposition or a two-consonant Biblical Hebrew particle along with it. Many Bible translations treat all these objects the same,” he says. “I wanted to try to understand why these variations occurred, so I looked at how different sentence elements might contribute to the variation. It was a fascinating study!” 
 
Kehrer believes it is important for university students to continue studying classical subjects like Hebrew. “I think we can all learn much from those who have gone before us, and so much wisdom and insight is connected to these ancient Biblical Hebrew texts, texts that would be inaccessible to us without translation,” he says. 

“I also think classical disciplines can help train students to think well and to read critically – essential skills for living in today’s ever-changing world.”  

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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