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04 May 2022
Robert Frater
The research efforts in the Department of Cardiothoracic Surgery in the Faculty of Health Sciences, UFS, have come a long way since the establishment of a homograft bank, animal research, and laboratory-based research on cardioplegia by Prof Hannes Meyer in the 1980s

Several world-class scientists and academics in the field of cardiovascular research will converge at the University of the Free State (UFS) on Thursday (5 May 2022) for a one-day hybrid conference to explore and celebrate the massive strides made in this critical field at the UFS Robert W M Frater Cardiovascular Research Centre.

The research efforts in the Department of Cardiothoracic Surgery in the Faculty of Health Sciences, UFS, have come a long way since the establishment of a homograft bank, animal research, and laboratory-based research on cardioplegia by Prof Hannes Meyer in the 1980s. Renewed interest in 2004 under the leadership of Prof Francis E Smit culminated in the establishment of the Robert W M Frater Cardiovascular Research Centre (the Frater Centre) in 2015. This was made possible through donor funding, especially by Dr Robert W M Frater MD PhD (honoris causa, UFS), a South Africa-born New York-based cardiothoracic surgeon, researcher and innovator as infrastructure and project support by the UFS.

The vision of the Frater Centre is to be a leading cardiovascular research institution in South Africa and sub-Saharan Africa. It provides an interdisciplinary training and research platform for scientists and clinicians from different backgrounds to develop as researchers and collaborators in cardiovascular and thoracic surgery and related domains. Activities are focused on the development of African solutions for African problems.

Three main divisions
The Frater Celebration day will highlight the achievements made thus far in a hybrid format in four sessions, which can be attended on a virtual platform or in person. The centre’s local and international collaborators will participate in the programme, and Dr Ronnie van der Merwe, the Group CEO of Mediclinic International, is the guest of honour.

The Frater Centre consists of three main divisions, all of which will form part of the focus of the conference programme in various forms during the day:

1) The Clinical Research Division addresses cardiovascular disease on a broad front, ranging from population and prevalence studies, healthcare solutions and clinical outcomes studies in a specific South African and African context.

2) The Research, Development and Commercialisation division is divided into Tissue Engineering and Cell Biology, Tissue Banking and Large Animal studies, and bioengineering to develop African solutions and technology within these domains.

3) The Simulation Programme provides an integrated interdisciplinary platform for the education and training of individuals and teams in cardiovascular, thoracic, anaesthetic, perfusion technology and related nursing fields in a state-of-the-art simulation unit. The research centre is developing a unique and leading programme and systems in this field. This endeavour is also developing IT models for training, evaluation and research.

The Frater Centre and 4IR
The Centre is firmly established in the fourth industrial revolution. It is new technology-driven, creating new IT platforms and boasts extensive interdisciplinary projects at the biomedical sector's local, national, and international levels.

It is essential to note that the extensive and successful collaboration within the Frater Centre not only exists on institutional level but also nationally and internationally. These collaborators assist, mentor, direct and contribute to the research activities.

Click: Link to the event
Event programme



News Archive

#Women'sMonth: Lack of HIV education still affects children
2017-08-17

Description: Nickie Goedhals Tags: Dr Nickie Goedhals, Medical Microbiology and Virology, The Lancet, transmission of HIV, National Research Foundation 

Dr Nickie Goedhals, Senior Lecturer and Pathologist
in Medical Microbiology and Virology at the UFS.
Photo: Sonia Small



“Despite all the advances in the management and prevention of HIV, children still become infected every day, often due to lack of education and access to health care.” This is according to Dr Nickie Goedhals, Senior Lecturer and Pathologist in Medical Microbiology and Virology at the University of the Free State (UFS).

Study published in UK medical Journal 
A case study she was part of and published in the UK medical journal The Lancet in 2012, demonstrates the transmission of HIV to a child through surrogate breastfeeding. This study is one of the many highlights in the young researcher’s career. She received her first rating from the National Research Foundation (NRF) in 2017 for the work she has done in Medical Virology over the past eight years.

According to the above-mentioned study, only about 1% of infants in South Africa are being breastfed by a surrogate. However, results from a study in the Free State showed that shared breastfeeding by a non-biological caregiver was the most important factor associated with HIV infection in discordant mother-child pairs. Therefore, continued education about the risk of HIV transmission is needed.

Dr Goedhals is also continuing with research on HIV by looking at HIV drug resistance. She is in the process of starting new projects focusing on HIV infection and drug resistance in infants.

PSP helped with NRF-rating
She says, although her NRF Y2-rating is the starting point of a research career, it shows that she is heading in the right direction, and it “gives access to research funds through the NRF for future projects.” Other important research she conducted was on Crimean-Congo haemorrhagic fever – the study for her PhD.

The Prestige Scholars Programme (PSP) at the UFS is the reason that she applied for the rating. “With all the service delivery, teaching, and administrative responsibilities of academic medicine, it is easy to lose focus. The PSP has really helped to create a focused and stimulating environment for research.” According to her, the PSP also provides access to a network of peers and senior staff at the UFS, as well as exposure to national and international experts.

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