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04 May 2022
Robert Frater
The research efforts in the Department of Cardiothoracic Surgery in the Faculty of Health Sciences, UFS, have come a long way since the establishment of a homograft bank, animal research, and laboratory-based research on cardioplegia by Prof Hannes Meyer in the 1980s

Several world-class scientists and academics in the field of cardiovascular research will converge at the University of the Free State (UFS) on Thursday (5 May 2022) for a one-day hybrid conference to explore and celebrate the massive strides made in this critical field at the UFS Robert W M Frater Cardiovascular Research Centre.

The research efforts in the Department of Cardiothoracic Surgery in the Faculty of Health Sciences, UFS, have come a long way since the establishment of a homograft bank, animal research, and laboratory-based research on cardioplegia by Prof Hannes Meyer in the 1980s. Renewed interest in 2004 under the leadership of Prof Francis E Smit culminated in the establishment of the Robert W M Frater Cardiovascular Research Centre (the Frater Centre) in 2015. This was made possible through donor funding, especially by Dr Robert W M Frater MD PhD (honoris causa, UFS), a South Africa-born New York-based cardiothoracic surgeon, researcher and innovator as infrastructure and project support by the UFS.

The vision of the Frater Centre is to be a leading cardiovascular research institution in South Africa and sub-Saharan Africa. It provides an interdisciplinary training and research platform for scientists and clinicians from different backgrounds to develop as researchers and collaborators in cardiovascular and thoracic surgery and related domains. Activities are focused on the development of African solutions for African problems.

Three main divisions
The Frater Celebration day will highlight the achievements made thus far in a hybrid format in four sessions, which can be attended on a virtual platform or in person. The centre’s local and international collaborators will participate in the programme, and Dr Ronnie van der Merwe, the Group CEO of Mediclinic International, is the guest of honour.

The Frater Centre consists of three main divisions, all of which will form part of the focus of the conference programme in various forms during the day:

1) The Clinical Research Division addresses cardiovascular disease on a broad front, ranging from population and prevalence studies, healthcare solutions and clinical outcomes studies in a specific South African and African context.

2) The Research, Development and Commercialisation division is divided into Tissue Engineering and Cell Biology, Tissue Banking and Large Animal studies, and bioengineering to develop African solutions and technology within these domains.

3) The Simulation Programme provides an integrated interdisciplinary platform for the education and training of individuals and teams in cardiovascular, thoracic, anaesthetic, perfusion technology and related nursing fields in a state-of-the-art simulation unit. The research centre is developing a unique and leading programme and systems in this field. This endeavour is also developing IT models for training, evaluation and research.

The Frater Centre and 4IR
The Centre is firmly established in the fourth industrial revolution. It is new technology-driven, creating new IT platforms and boasts extensive interdisciplinary projects at the biomedical sector's local, national, and international levels.

It is essential to note that the extensive and successful collaboration within the Frater Centre not only exists on institutional level but also nationally and internationally. These collaborators assist, mentor, direct and contribute to the research activities.

Click: Link to the event
Event programme



News Archive

Plant-strengthening agent a result of joint effort between UFS and German company
2015-07-27

Research over the past few years has showed that the agent applied mostly as a foliar spray subsequently leads to better seedlings as well as growth and yield enhancement of various crops.

The application of a plant-strengthening agent in the agricultural industry has, until recently, been largely ignored, says Dr Elmarie van der Watt of the Department of Soil, Crop, and Climate Sciences at the University of the Free State (UFS). The agent was co-developed by researchers at the UFS and a German company.

The product is moving into new markets, such as China, Vietnam, the USA, and Australia.

ComCat® was the result of extensive research by the German company Agraforum AG. Commercialisation was limited initially to Europe, while research was expanded to other parts of the world, with the University of the Free State as the main research centre.  ComCat® is a unique, non-toxic plant strengthening agent derived from wild plants. It enhances plant growth and yield, as well as resistance against abiotic and biotic stress factors.

Dr Van der Watt says that, in nature, plants communicate and interact by means of allelochemicals (the inherent silent tool of self-protection among plants) and other phytochemicals (chemical compounds that occur naturally in plants), as part of their resistance mechanisms towards biotic and abiotic stress conditions.

Most wild-plant varieties are usually well-adapted to resist these stress factors. However, monoculture crops have lost this ability to a large extent. “Active compounds contained in extracts from wild plants applied to monoculture crops can potentially supply the signal for the latter to activate their dormant resistance mechanisms.” 

Research over the past few years has showed that the agent applied mostly as a foliar spray subsequently leads to better seedlings as well as growth and yield enhancement of various crops.  A major advantage is that, despite its enhancing effects on root development and yield, it does not induce unwanted early vegetative growth that could jeopardise the final yield, as happened in the past for nitrogen application at an early growth stage. 

Dr Van der Watt says, “Physiological data on the effect of the natural bio-stimulant product on photosynthesis, respiration, and resistance towards biotic stress conditions indicate that it can be regarded as a useful tool to manipulate agricultural crops. Research also showed that the field of application for this natural product is never-ending, and new applications are being investigated every day.”

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