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10 May 2022 | Story Anthony Mthembu | Photo Supplied
Alina Ntsiapane
Alina Ntsiapane obtained second place in the partners division of the ILRI CapDev Grand Challenge research pitching contest.

Alina Ntsiapane, a PhD student at the University of the Free State, obtained second place in the partners category of the International Livestock Research Institute’s (ILRI) CapDev Grand Challenge research pitching contest, which took place on 13 April 2022. The pitching contest is the first part of the CapDev Grand Challenge, which is a 10-month process aimed at equipping scientists with the necessary skills to contribute to new research. 

Presenting Research to a Tough Panel of Judges 

Ntsiapane was one of 30 contestants who presented their research virtually to a panel of esteemed judges. “It was not easy, it was very challenging for me because it was my first time presenting my PhD study and I had to do it live on an international platform,” expressed Ntsiapane. Although each contestant is thoroughly prepared for their respective presentations, Ntsiapane argues that some of the questions asked by the judges can be quite daunting. “Some of their questions were very challenging and I did not know how to respond to them, but they made me aware of ways in which I needed to improve my research,” she stated. However, regardless of the intensity of the pitching contest, Ntsiapane’s research allowed her to progress to the next stage of the CapDev Grand Challenge. She will be part of the rigorous 10-month training process that will begin in June 2022.

Ntsiapane’s Research Project

Ntsiapane’s PhD research focuses on the production of smallholder wool as a means to improve livelihoods in both Thaba ’Nchu and Botshabelo in the Free State. In fact, in the research Ntsiapane highlights that there has been a significant decline in the production of wool within the last three decades. As such, Ntsiapane believes it is imperative to create spaces that allow for the training of small-scale farmers, so that the production of wool can still be a possibility.
Consequently, Ntsiapane hopes that the 10-month training she will receive from the CapDev Grand Challenge will not only allow her to grow but will assist in opening doors for her. “I’m hoping to get exposure and to make connections with policy makers and the donors as well. This will assist me in achieving my goals,” she explained. 

Future Endeavours After the Training Course

Subsequent to the training course, Ntsiapane would like to utilise that knowledge by continuing to make her most recent project a reality. Ntsiapane is currently working on developing a television show aimed at providing adequate training to small-scale farmers, so that they are equipped with the necessary knowledge and understanding of the industry in which they find themselves. As such, being part of the CapDev Grand Challenge will allow her to learn some of the necessary ways in which this dream could become a reality. 

News Archive

Nanotechnology breakthrough at UFS
2010-08-19

 Ph.D students, Chantel Swart and Ntsoaki Leeuw


Scientists at the University of the Free State (UFS) made an important breakthrough in the use of nanotechnology in medical and biological research. The UFS team’s research has been accepted for publication by the internationally accredited Canadian Journal of Microbiology.

The UFS study dissected yeast cells exposed to over-used cooking oil by peeling microscopically thin layers off the yeast cells through the use of nanotechnology.

The yeast cells were enlarged thousands of times to study what was going on inside the cells, whilst at the same time establishing the chemical elements the cells are composed of. This was done by making microscopically small surgical incisions into the cell walls.

This groundbreaking research opens up a host of new uses for nanotechnology, as it was the first study ever in which biological cells were surgically manipulated and at the same time elemental analysis performed through nanotechnology. According to Prof. Lodewyk Kock, head of the Division Lipid Biotechnology at the UFS, the study has far reaching implications for biological and medical research.

The research was the result of collaboration between the Department of Microbial, Biochemical and Food Biotechnology, the Department of Physics (under the leadership of Prof. Hendrik Swart) and the Centre for Microscopy (under the leadership of Prof.Pieter van Wyk).

Two Ph.D. students, Chantel Swart and Ntsoaki Leeuw, overseen by professors Kock and Van Wyk, managed to successfully prepare yeast that was exposed to over-used cooking oil (used for deep frying of food) for this first ever method of nanotechnological research.

According to Prof. Kock, a single yeast cell is approximately 5 micrometres long. “A micrometre is one millionth of a metre – in laymen’s terms, even less than the diameter of a single hair – and completely invisible to the human eye.”

Through the use of nanotechnology, the chemical composition of the surface of the yeast cells could be established by making a surgical incision into the surface. The cells could be peeled off in layers of approximately three (3) nanometres at a time to establish the effect of the oil on the yeast cell’s composition. A nanometre is one thousandth of a micrometre.

Each cell was enlarged by between 40 000 and 50 000 times. This was done by using the Department of Physics’ PHI700 Scanning Auger Nanoprobe linked to a Scanning Electron Microscope and Argon-etching. Under the guidance of Prof. Swart, Mss. Swart en Leeuw could dissect the surfaces of yeast cells exposed to over-used cooking oil. 

The study noted wart like outgrowths - some only a few nanometres in diameter – on the cell surfaces. Research concluded that these outgrowths were caused by the oil. The exposure to the oil also drastically hampered the growth of the yeast cells. (See figure 1)  

Researchers worldwide have warned about the over-usage of cooking oil for deep frying of food, as it can be linked to the cause of diseases like cancer. The over-usage of cooking oil in the preparation of food is therefore strictly regulated by laws worldwide.

The UFS-research doesn’t only show that over-used cooking oil is harmful to micro-organisms like yeast, but also suggests how nanotechnology can be used in biological and medical research on, amongst others, cancer cells.

 

Figure 1. Yeast cells exposed to over-used cooking oil. Wart like protuberances/ outgrowths (WP) is clearly visible on the surfaces of the elongated yeast cells. With the use of nanotechnology, it is possible to peel off the warts – some with a diameter of only a few nanometres – in layers only a few nanometres thick. At the same time, the 3D-structure of the warts as well as its chemical composition can be established.  

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za  
18 August 2010
 

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