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26 May 2022 | Story Leonie Bolleurs | Photo Leonie Bolleurs
UFS South Campus Creative clubs Initiative
UFS staff members from the Social Responsibilities Projects, Patience Aba, Judith Lefa, Noluthando Zwane, Dr Angela Stott, and Queen Selema, with a group of learners from the Ikaelelo Senior Secondary School looking at the effect of wind on the evaporation rate of water. This is one of the science experiments used as exemplars to stimulate the learners to plan their own science expo projects.

“This class teaches us how things work, and it gives us many ideas.” These are the words of Bokamoso Mahlasi, a Grade 9 learner at Ikaelelo Senior Secondary School, who says he dreams of becoming a radiologist one day. 

He is part of a group of 100 Grade 9 learners from schools around Bloemfontein, who – once a week for two hours – have the opportunity to learn more about mathematics, science, coding and to prepare science expo projects. This is made possible through the Creative Clubs programme, an initiative of the Social Responsibility Projects on the University of the Free State (UFS) South Campus. 

An opportunity to expand horizons

Dr Angela Stott, Researcher and Teacher Educator in the Social Responsibilities Projects, believes that they are providing township learners, who tend not to have much access to extracurricular opportunities, the chance to expand their horizons, obtain problem-solving and reasoning skills, and increase their interest in mathematics, science, and coding through a range of extracurricular extension activities.

Dr Joleen Hamilton, initiator and coordinator of this programme, says, “The learners attending these sessions are achievers in the current school system. Teachers often don’t have time to give extra stimulation to higher-achieving learners. With Creative Clubs, we want to address that gap.”

She continues: “Besides creating an interest in mathematics, science, and coding, we also focus on building self-esteem and confidence. Our thinking is that if learners believe in themselves, they are more willing to take on challenges. Developing skills such as perseverance and reflection form part of our focus as well. With some of the activities we also give learners the opportunity to work as a team, preparing them for real-life situations where one often needs to work in a group setting. By developing the mentioned skills, we aim to empower learners to excel in different areas.”

The importance of mathematics in real life

During the Creative Clubs sessions, a series on the basics of doing a science expo project is presented to stimulate interest in this competition and to guide the learners in planning their own science expo projects. Dr Stott adds that they are also presenting a session on extracurricular mathematics activities. “This includes problem-solving tasks, brain teasers, and games. We emphasise the importance and use of mathematics in real life,” explains Dr Hamilton.

We also focus on building self-esteem and confidence. Our thinking is that if learners believe in themselves, they are more willing to take on challenges. – Dr Joleen Hamilton

Also in the pipeline is a planned outing to the Naval Hill Planetarium, as well as a session introducing coding, where learners will be playing the Boats and Tanks coding game, teaching them the basic coding commands. 


News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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