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30 May 2022 | Story Leonie Bolleurs | Photo Leonie Bolleurs
Taking the lead to positively impact
Attending the graduation ceremony in the short learning programme: Teacher Professional Development for Digital Mobile Learning, and Entrepreneurship for SMMEs, were, from the left: Lintle Nthati Radikgomo, Thabile Sylvia Masangane, and André Uys from the Flavius Mareka College in Sasolburg, and Thandeka Mosholi from the UFS.

Gym instructor, homework centre owner, fashion designer, photographer. These are but some of the students who walked across the stage to receive their qualifications after completing an entrepreneurship programme on the South Campus of the University of the Free State (UFS).

The Department of Social Responsibility, Enterprise and Community Engagement on the South Campus recently hosted a ceremony for students in the short learning programme: Teacher Professional Development for Digital Mobile Learning, and Entrepreneurship for SMMEs.

According to Thakane Nteko from the Social Responsibility Projects (SRP), 40 of the 66 students enrolled for the qualification in lecture development completed it, together with the 10 students who registered for the entrepreneurship programme. The students are mainly university and TVET (Technical and Vocational Education and Training) lecturers and self-employed youth.

She says the department aims to enhance teaching and learning in the Free State, be it for school learners, schoolteachers, TVET college lecturers, or the youth. Key in this initiative is the UFS, in partnership with Sector Education and Training Authorities (SETAs) and other organisations involved in community development, to make a positive difference in communities where there is a need.

Addressing social injustices
Positively impacting the youth of South Africa is of critical importance to the UFS. “Creating opportunities and growth through leading, learning, and teaching, is not only valid for the young intellectuals who have the chance to qualify themselves through tertiary studies. It is also applicable to the disadvantaged communities exposed to poor education. The UFS SRP serve as the vehicle to address this social injustice,” states Thandeka Mosholi, Head of the Department of Social Responsibility, Enterprise and Community Engagement.

She trusts that Social Responsibility Projects has established itself as a supporter of disadvantaged communities by responding to the call to positively impact the future of South African youth. “Our passion resonates with those who desire to open opportunities and bring purpose to gifted learners born in circumstances they did not choose, by being leaders in school change,” she says.

Destined for greatness
Delivering messages of encouragement at the event was KB Lebusho, CEO of the Free State Chamber of Commerce and Industry. Addressing the group of entrepreneurs, lecturers, and teachers, he told them that they are destined for greatness. “But until you believe in yourself, things will not change for you. It is important that you have clarity about your dreams and goals.”

Advocate Shirly Hyland, Director: Kovsie Phahamisa Academy, also left the students with a message of support. “By paying education forward, we can change the world. The power to touch the lives around you, lies in your hands. Enjoy taking the knowledge you have learned into your communities,” she said.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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