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05 May 2022 | Story Leonie Bolleurs | Photo Supplied
Prof Hennie van Coller and Prof Hendrik Swart
Prof Hennie van Coller, left, received the the NP van Wyk Louw medal, and Prof Hendrik Swart, right, received the Havenga Prize for Physical Sciences.

The board of the Suid-Afrikaanse Akademie vir Wetenskap en Kuns (SAAWK) recently (22 April) announced the winners of the 2022 prizes. The academy, which was established in 1901, aims to promote the use of Afrikaans in science and the arts.

Havenga Prize for Physical Sciences

Prof Hendrik Swart, NRF B1-rated researcher, SARChI Research Chair in Solid-state Luminescent and Advanced Materials, and Senior Professor in the Department of Physics at the University of the Free State (UFS), received the prestigious Havenga Prize for Physical Sciences.

He says it is an honour to receive this award. “When I look at the list of names that have received the award in the past, I am very humbled and surprised to receive such an award.”

The Havenga Prize, for which candidates are specifically judged on research publications and evidence of their promotion of Afrikaans, has been awarded annually for the past 77 years for original research in the natural sciences or a technical field. 

A collaboration with researchers from the Nelson Mandela University (NMU) on semiconductor materials that improve the efficiency of solar cells, resulted in Prof Japie Engelbrecht (Emeritus Professor, NMU) nominating Prof Swart for this award. He is involved in an NRF collaborative research project with NMU and Linköping University in Sweden.

Prof Swart has played an important role in the acquisition of numerous research devices for analysing the thin layer of phosphor, and the semiconductor devices that can be made from such materials. His research and zeal for his work led to the establishment of the national nano-surface characterisation facility (NNSCF) containing state-of-the-art surface characterisation equipment. 

The PHI Quantes XPS system, for instance, is the first in Africa and one of only 20 in the world. The Quantes XPS system uses X-rays to determine the chemical composition of molecules on the surface of a sample. The system is unique in the sense that it also has an extra X-ray source that can determine the chemical state below the surface, which was not possible in the past. This will help to dictate the position of defects in phosphor materials, which will consequently enable the department to create better phosphor for solid-state lighting as well as solar cell applications.

The most meaningful for him, however, was the production of several well-trained postgraduate students and the generation of high-impact, well-cited scientific publications.

This award, one of several awards he has received during his career, does not signify the end of the road. On the contrary, he is looking forward to improving solar cells by using the phosphor materials they have manufactured, applying it on glass windows doped with phosphors to generate electricity.

NP van Wyk Louw Medal and Alba Bouwer Prize for children's literature

The NP van Wyk Louw Medal was awarded to Prof Hennie van Coller, a researcher who is also affiliated to the UFS. Prof Van Coller, currently an emeritus outstanding professor and research fellow at the university, was a former Head of the UFS Department of Afrikaans and Dutch, German and French, as well as Chairperson of SAAWK. He is known for his impact on the literary world, both locally and internationally, through the quality of his scientific articles and books. 

According to SAAWK, the body awards the NP van Wyk Louw Medal for a person’s creative contributions to the exploitation, organisation, and continuous development of a section of the humanities, significantly contributing to the advancement of the humanities.

Jaco Jacobs, the children’s author of more than 170 books who recently presented the 35th DF Malherbe Memorial Lecture at the UFS, was also awarded for his work. Jacobs, also a UFS alumnus, received the Alba Bouwer Prize for children's literature. The prize, which is awarded every three years, was presented to Jacobs for the book Die boekwinkel tussen die wolke, written during the COVID-19 lockdown period. 

SAAWK will present the awards later this year during two virtual award ceremonies in July. 

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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