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07 November 2022 | Story Edzani Nephalela | Photo Supplied
Delegates from various schools as well as the Free State Department of Education receive the book donations that will be distributed to 30 high schools in the Sasolburg region.

Statistics indicate that individuals who have difficulty reading are less motivated to read or visit the library, because they cannot recognise words, grasp, or understand what they read. Various organisations, including the University of the Free State (UFS), are addressing this issue by encouraging a reading culture and providing the required resources to enhance their reading skills.

The UFS, in collaboration with Zubeida Jaffer – an award-winning South African journalist, author, and activist – donated books to various secondary schools in the Fezile Dabi district, one of the five districts in the Free State.
Thandeka Mosholi, the Project Leader, said that impacting the youth of South Africa is a critical objective for the UFS Social Responsibility Projects (UFS SRP), which served as the vehicle to address this social injustice. The UFS SRP has established itself as an agent of change and friend of disadvantaged communities.

“In alliance with sponsors who embody compassion and integrity, we respond to the obligation to positively impact the future of South African youth. Our passion resonates with those who desire to open opportunities and bring purpose to learners born in circumstances they did not choose, by being leaders in school change. We believe this contribution will promote reading in schools, because children struggle to grow academically without reading and comprehension skills, as reading is the foundation of all academic subjects. Reading also influences the learner’s ability to write. So, instilling a love of reading at an early age is the key that unlocks the door to lifelong learning,” Mosholi explained.

Exposure to the past, present, and a peek into the future

The event, hosted at Cedar Secondary School in Sasolburg, saw books donated to 30 high schools to foster a reading culture among learners. The following books were donated: Beauty of the heart, Love in the times of treason, and Our generation. It covers 130 years of South African history, and are about three women – Charlotte Maxeke, Ayesha (Bibi) Dawood, and the author herself, Zubeida Jaffer.

“This initiative is to expose as many educators, learners, and students as possible to this collection, since it provides a firm foundation to make sense of our past, present, and future. These books are not to keep us stuck in the past, but to help us navigate the present. We have secured additional sponsorship from Old Mutual, which made it possible to reach schools in all provinces. I thank the University of the Free State for helping to identify schools in the Free State and joyfully distributing these books,” said Jaffer.

On the contrary, school officials are ecstatic, saying that the books will motivate their learners to promote education, learn about their past, and improve their vocabulary. “A school cannot survive in isolation; through the academics’ teaching and learning, as well as research in their respective fields, we learn a lot. Thus, the university's cooperation is welcomed. Through these books, learners will be inspired to reinvent, repurpose, and rediscover libraries," said Sindiswa Mcosana, Curriculum Primary Schools Chief Education Specialist at the Free State Department of Education.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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