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29 November 2022 | Story Andre Damons | Photo Andre Damons
Prof Motlalepula Matsabisa
Prof Motlalepula Matsabisa, Director of Pharmacology in the Department of Pharmacology at the UFS, hosted the first IKS Bio-Trade Indaba, which took place between 24 and 25 November on the Bloemfontein Campus of the UFS.

The inaugural international Indigenous Knowledge and Bio-Trade Indaba, hosted by the University of the Free State (UFS) in collaboration with the Technology Innovation Agency (TIA) – an entity of the Department of Science and Innovation (DSI) – is the ideal platform for various stakeholders to network and share knowledge on current developments in indigenous knowledge research and product development, biodiversity, conservation, innovation, and commercialisation of the IK-based researched products. 

The IKS Bio-Trade Indaba was championed by the university’s African Medicines Innovation and Technology Development Platform (AMITD), which is funded by TIA. AMITD was established to stimulate economic growth by providing science-based solutions and developing technologies that would utilise indigenous knowledge and South African biodiversity to produce high-quality African traditional-medicine-based proprietary products, focusing on priority diseases. AMITD is a national leader in research, development, and formulation research on traditional medicines and has a strong history in IKS research, community collaboration, and participation initiatives, as well as partnerships with industry on herbal medicines.

The indaba, which took place from 24 to 25 November, was a success, opening much-needed dialogue and engagement on the role of IK-based knowledge in research and commercialisation. Going forward, the indaba will be a vital platform to enhance the role of IKS in inclusive development and transformation.

African traditional medicine should be internationally recognised

Prof Motlalepula Matsabisa, Director of Pharmacology in the UFS Department of Pharmacology and AMITD, said he has a special interest in the pharmacology of traditional medicines and that he wants to see more national, continental, and international collaboration so that the dream of making ATM internationally recognised and a global force can be realised. 

“How do we develop new drugs and medicines based on the knowledge we have. We do this without compromising on good all-inclusive science on ATM. We should take the science and put it on the global stage so that all people will begin to respect it,” said Prof Matsabisa. 

According to him, research conducted by AMITD should address national research priorities, community research needs and aspirations to respond to industry research questions and challenges and develop products, intellectual property (IP), as well as commercialisation. “Research needs to have a societal impact and must impact the quality of life of people. We do responsive research that needs to address old diseases, new diseases, neglected diseases, current pandemics, as well as new and re-emerging pandemics.” 

Elevation of IKS profile can no longer be delayed
 
Dr Vuyisile Phehane, Executive: Bio-Economy at the TIA, said the indaba came at a time when the elevation of the profile of IKS can no longer be delayed. TIA acknowledges the rich, largely untapped source of knowledge within communities that has yet to be fully exploited for the economic and social benefit of particularly the underserved regions of the country, and it should be systematically well researched. 

Dr Vuysile Phehane
Dr Phehane, gave a message of support from TIA, saying the indaba came at a time when the elevation of the profile of IKS can no longer be delayed. (Photo: Andre Damons)


“Sectoral support priorities in agriculture, manufacturing, health innovations, and allied health cannot be overlooked, and neither can the various master plans created to support industrial sectors. This thought leadership has a direct bearing on what we are doing here, engaging in dialogue to shape our future, and seeking ways to collaborate and build long-lasting partnerships in the space of IKS. These partnerships not only serve us in the country, but also on the African continent,” said Dr Phehane. 

According to him, TIA played the role of industry builder and sought to increase its efforts to grow and enhance the role of IKS in inclusive development and transformation. The successful commercialisation of all indigenous knowledge-based projects involving the use of indigenous plants requires the capacity to commercially cultivate these plants. 

Dr Phehane said TIA funded AMITD to ensure that the products of promising indigenous knowledge innovations are safe, effective, and of consistently high quality. “This platform seeks to address generations of market failure by bringing IK into the mainstream of commercialisation and truly equitable benefit sharing. Going forward, 20% of our annual MTEF allocation will be channelled towards IK initiatives, which is significant. This is testament to our commitment to IKS.”

The two-day indaba hosted various panel discussions on multiple aspects of IKS research and developments in human and plant health. Among these were discussions on cannabis research to mitigate cancer multidrug resistance, phytoconstituents for the treatment of diabetes, the development of PHELA, a plant-based product as a treatment for COVID-19, natural product-based colon regulator commercialisation, the development of cannabis and other medicinal plants in wound healing and developing hydrogels, as well as the development of IK-based herbal pesticides.

Discussions also focused on new developments in the indigenous health infusion industry, developments in medicine regulations and IK-based clinical trials in South Africa, as well as African medicines research internationalisation. International panellists included Prof Minke Tang (Beijing University of Chinese Medicine), Dr Samuel Obakiro (HOD, Department of Pharmacology, Busitema University, Uganda), and Dr Kofi Donkor (Centre for Plant Medicine Research, Mampong, Ghana), all of whom shared experiences on IKS-related research in their respective countries.

IKS one of the areas targeted for investment and growth 

Dr Glen Taylor, Senior Director: Research Development at the UFS, said the Department of Pharmacology is one of the fastest-growing departments in the Faculty of Health Sciences at the UFS, and attracts a large number of applications from national and international scholars largely due to a very understated Prof Matsabisa.

“We always look at areas where we need to invest in the future and grow, and IKS is one of those areas we targeted and invested in significantly. Through the research and work in IKS, this is done to reposition the institution as a research-led university that is relevant to its communities and societies.” 
The TIA UFS IKS International Indaba was funded by the TIA IKS unit and the Department of Pharmacology – AMITD platform.

News Archive

Chemistry research group receives international recognition
2016-10-28

Description: Chemistry research group  Tags: Chemistry research group

Dr Carla Pretorius mounts microcrystals with
Dumisani Kama while Pennie Mokolokolo
observe the technique.
Photo: Supplied


Crystals and crystallography form an integrated part of our daily lives, from bones and teeth, to medicines and viruses, new catalysts, jewellery, colour pigments, chocolates, analysing rocks on the moon and Mars, electronics, batteries, metal blades in airplane turbines, panels for solar energy and many more.

In spite of this, not many people know much about X-ray crystallography, although it is probably one of the greatest innovations of the 20th century, spanning the sciences. That is why this discipline is actively researched by a number of tertiary institutions around the globe as well as the Inorganic Chemistry Group of the Department of Chemistry at the University of the Free State (UFS).

Research by the Inorganic Chemistry Group includes:
•    clever design of model medicines to better detect cancer and study heart, bone and brain defects;
•    production of new compounds for making new and better automobile fuels and decrease carbon dioxide in the atmosphere;
•    generation and purification of new South African mineral resources for metals widely used in turbines which use wind energy.

A group of UFS students have received acknowledgement for their research at six international venues in the past few months.

Posters in Cameroon
Twelve postgraduate students, together with Prof André Roodt, Head of the Inorganic Chemistry division at the UFS, delivered three oral presentations, nine posters, one plenary and one keynote lecture abroad.

Four UFS students - Nina Morogoa, Pheello Nkoe, Alebel Bilay, and Mohammed Elmakki - who delivered posters at the First Pan African Conference on Crystallography in Dschang, Cameroon, received prizes for their presentations.

School and conference in Croatia

Students Orbett Alexander and Dumisani Kama were selected to attend the intense and demanding Third European Crystallographic School in Bôl, Croatia. Both Kama, Alexander and Prof Roodt gave oral presentations at the 24th Croatian-Slovenian Crystallographic Meeting at Brac Island, Croatia.

Kama, together with Dr Ferdi Groenewald, Dr Carla Pretorius and Pennie Mokolokolo, also attended the European Synchrotron Radiation Facility (ESRF) in Grenoble, France. The ESRF is a centre of excellence for fundamental and innovation-driven research. The storage ring at this laser facility can generate X-rays 100 billion times brighter than typical medical and laboratory X-ray sources.

Research in Switzerland

Kama and Mokolokolo also spent one month on research visits at the University of Zurich in Switzerland. Both Kama and Alexander were invited to present their research orally to the Institute of Inorganic Chemistry in Zurich, headed by Prof Roger Alberto.

In Basel, Switzerland, Dr Ferdi Groenewald, Dr Renier Koen, and Dr Truidie Venter all presented their research at the 30th European Crystallographic Meeting.

Prof Roodt said: “It is incredibly important that our postgraduate students get the chance to interact, discuss, and be taught by the best in the world and realise that hard work on basic and applied chemistry processes leads to broader recognition. The delegates to these international venues came from more than 60 countries and took note of our students work. With these young researchers, our future at the UFS and at Inorganic Chemistry is in good hands”.

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