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23 November 2022 | Story André Damons

The Department of Pharmacology at the University of the Free State (UFS), together with the Technology Innovation Agency (TIA), is hosting the first Indigenous Knowledge and Bio-Trade Indaba on the Bloemfontein Campus. The Department of Science and Innovation (DSI) and TIA are the sponsors of the event. 

Prof Motlalepula Matsabisa, Professor and Director of Pharmacology, will play host to the various stakeholders to network and share knowledge on current developments in indigenous knowledge research and product development, biodiversity, innovation, and commercialisation of the IK-based research products. The Indigenous Knowledge System (IKS) for Health unit in the Department of Pharmacology within the UFS Faculty of Health Sciences was last year awarded an annual Technology Innovation Agency Platform (TIA) grant of R17 million for the next five years.

The research and teaching programme in the School of Clinical Medicine has since been rebranded and is now known as the African Medicines Innovation and Technology Development Platform (AMITD), which will strive to respond to community health needs and address industry research needs and challenges.

The indaba will showcase progress made by TIA and other entities in enriching the development and commercialisation of IK-based innovations. It will take place from 24 to 25 November 2022 in the Equitas Senate Hall at the UFS. 

Prof Matsabisa is the chairperson of the World Health Organisation’s (WHO) Regional Expert Advisory Committee on Traditional Medicines for COVID-19. He is also a visiting professor at the Beijing University of Chinese Medicine (BUCM) in Beijing, China, and the Deputy President of the South African Society for Basic and Clinical Pharmacology.
 

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Plant scientist, Prof Zakkie Pretorius, contributes to food security with his research
2014-08-26

 
Many plant pathologists spend entire careers trying to outwit microbes, in particular those that cause diseases of economically important plants. In some cases control measures are simple and successful. In others, disease management remains an ongoing battle. 

Prof Zakkie Pretorius, Professor in the Department of Plant Sciences, works on a group of wheat diseases known as rusts. The name is derived from the powdery and brown appearance of these fungi.

Over the course of history wheat rusts have undergone what are notoriously known as boom and bust cycles. During boom periods the disease is controlled by means of heritable resistance in a variety, resulting in good yields. This resistance, though, is more often than not busted by the appearance of new rust strains with novel parasitic abilities. For resistance to remain durable, complex combinations of effective genes and chromosome regions have to be added in a single wheat variety.

In recent years, Prof Pretorius has focused on identifying and characterising resistance sources that have the potential to endure the onslaught of new rust races. His group has made great progress in the control of stripe rust – where several chromosome regions conditioning effective resistance have been identified.

Dr Renée Prins of CenGen and an affiliated UFS staff member, developed molecular markers for these resistance sources. These are now routinely applied in wheat breeding programmes in South Africa. In addition, Prof Pretorius collaborates with several countries to transfer newly discovered stem rust resistance genes to wheat, and in characterising effective sources of resistance in existing wheat collections.

His work is closely supported by research conducted by UFS colleagues, students and other partners on the genetics of the various wheat rust pathogens. These studies aim to answer questions about:
• the origin and relatedness of rust races,
• their highly successful parasitic ability, and
• their adaptation in different environments.

The UFS wheat rust programme adds significantly to the development of resistant varieties and thus more sustainable production of this important crop. 

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