Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
14 October 2022 | Story Dr Cinde Greyling | Photo Iflair Photography
UFS Business school
The UFS Business School.

The University of the Free State Business School (UFSBS) was established in the late 1990s and is fully accredited by the Council on Higher Education (CHE) and the Central and East European Management  Development Association (CEEMAN). Since its inception, the school has operated as a boutique business school focusing on personal attention to adult learners.

Late 2021, the UFSBS appointed a new Director, Dr Udesh Pillay. In conjunction with the change in leadership, the UFSBS is embarking on a new strategic journey, while maintaining the focus on its core business – in other words, its official academic offerings. The strategic journey of the UFSBS has been underway for the past year, and significant time has been allocated to the recurriculation of programme offerings; decolonisation of the academic agenda; and orientating the UFSBS so that it makes a larger practical contribution to the SME sector locally and nationally, especially in relation to business continuity and resilience in the wake of unforeseen externalities.  These developments will ensure that the UFSBS remains a premier academic institution and contributes to the success of South Africa and its people. It also ensures that the twin principles of academic excellence and social justice become mutually reinforcing.

The UFSBS’s strategic direction for the next five years aligns neatly with the Vision 130. By 2034 – when the university commemorates its 130th anniversary – the UFS wants to be recognised and acknowledged by peers and society as a top-tier university in South Africa. Similarly, the UFSBS has aspirations to become a top-ten business school in SA over the next five years.

Given the history of South Africa, it is of utmost importance to empower people to add value, particularly in the field of business and management leadership. The UFSBS will contribute to building an ecosystem of entrepreneurialism, with the more traditional academic programmes based upon the conventional practices of teaching and learning, research, and mentorship to be supplemented by ‘opportunity-driven initiatives’, such as executive education, consulting support, coaching, incubation services, and the commercialisation of intellectual property.

Globally, the Fourth Industrial Revolution (4IR) has catalysed processes of digital transformation in business, to which the UFSBS will align to ensure that students are equipped with the relevant knowledge and skills in a fast-changing, technology-enabled world. With the support of the Centre for Business Dynamics (CBD) housed in the UFSBS; the establishment of the Small Business Academy (SBA) in early 2024 in the UFSBS; the soon-to-be-established High-Growth Business Incubator (in collaboration with the NAS faculty); and with the process of strengthening relationships with the Paradys Experimental Farm gaining traction, a differentiated medium has been created to nurture responsible,  ethical, and socially conscious business leaders. The foundation then – to create the next generation of business leaders and entrepreneurs to become agents of change and value co-creators for business and society – will thus have begun.

The UFSBS will align to ensure that students are equipped with relevant knowledge and skills in a fast-changing, technology-enabled world. – Dr Udesh Pillay.
The slogan, ‘BE WORTH MORE’, embodies what the UFSBS strives for, and is consistent with new developments in global discourses, which are rethinking and transforming many of the traditional dogmas that have informed the mandates of business schools. 

As a critical bridge between academia and business, the UFSBS is uniquely poised to reimagine a better and intelligent future that is data-informed, collaborative, innovative, and inclusive.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept