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A look into the Future of South Africa

27 September 2022 | Story Dr Nitha Ramnath

2022 UFS Thought-Leader Series

PRESENTS

a panel discussion titled

A look into the Future of South Africa

Join online at livestream.ufs.ac.za

The University of the Free State is pleased to present the UFS Thought-Leader panel discussion titled, A look into the future of South Africa, which is part of the 2022 Thought-Leader Series. As a public higher-education institution in South Africa with a responsibility to contribute to public discourse, the University of the Free State (UFS) will be presenting the panel discussion in collaboration with the Free State Literature Festival and News24. This event will bring together expert thought leaders such as Moeletsi Mbeki, Pieter du Toit, and Dr Mareve Biljohn to share insights on the social, political, economic, and business landscape of South Africa and what it means for our future. The panel discussion will be facilitated by Prof Francis Petersen, Rector and Vice-Chancellor of the UFS.

Panel discussion presented on 6 October 2022

South Africa is at a precipice – unemployment is at an all-time high, almost half the population receives income from the state every month, there is an absence of policy systems with no leadership in the country at all levels, and complete distrust exists between government and communities. The current national administration has no interest in creating an environment for entrepreneurship and growth. The expectation of investment to grow the economy is far-fetched. An increase in privatisation is taking place and gaining moment in areas such as security and provision of electricity, among others. As we approach the end of 2022 and reflect on the year that was, what opportunities are there to regain the confidence of our nation, establish much-needed credibility globally, and charter our country into a prosperous and successful terrain – where do we see ourselves? These are some of the aspects we look forward to discussing with the esteemed panel.

Date: Thursday 6 October 2022
Time: 10:00-12:00
Venue: Albert Wessels Auditorium, Bloemfontein Campus
RSVP: https://events.ufs.ac.za/e/ThoughtLeaderFutureofSouthAfrica

Refreshments will be served.

For further information, contact Alicia Pienaar at pienaaran1@ufs.ac.za.

Some of the topics discussed by leading experts in 2021 included, among others, reimagining universities for student success; corruption in South Africa – the endemic pandemic; South African politics and the local government elections; is South Africa falling apart: where to from here; predications for 2022; and why vaccinate? This year’s webinar series commenced on 31 May 2022 with the topic Crime in South Africa – who is to blame? This was followed by webinars held in July and September, respectively titled Are our glasses half full or half empty? and What needs to be done to POWER up South Africa?

Facilitator:

Prof Francis Petersen
Rector and Vice-Chancellor, UFS

Panellists:

Moeletsi Mbeki
Deputy Chairperson
The South African Institute of International Affairs (SAIIA)

Pieter du Toit
Assistant Editor
In-depth news
News24

Dr Mareve Biljohn
Head: Department of Public Administration and Management
University of the Free State

Bios of speakers:

Moeletsi Mbeki

Mr Moeletsi Mbeki is a political analyst, author, and entrepreneur. He is a director of several companies, Chairman of KMM Investments (Pty) Limited, KMM Review Publishing (Pty) Limited, MGM Capital Investments (Pty) Limited, and Executive Chairman of Pomegranate Media (Pty) Ltd. Mr Mbeki is the author of Architects of Poverty: Why African Capitalism Needs Changing. He edited Advocates for Change: How to Overcome Africa’s Challenges. Both books have been translated into Chinese. He recently co-authored A Manifesto for Social Change: How to Save South Africa with his niece, Dr Nobantu Mbeki. He is Deputy Chairman of the South African Institute of International Affairs (SAIIA) – an independent think tank based at the University of the Witwatersrand – and is a member of the council of the International Institute for Strategic Studies (IISS), which is based in London. After returning to South Africa from exile in 1990, he was appointed Head of Communications for the Congress of South African Trade Unions (Cosatu), and Media Consultant for the African National Congress. During most of the 1980s, he was a senior journalist for Zimbabwe Newspapers in Harare. As a result of the outstanding work that he did for the Zimbabwe Newspapers Features Department, he was awarded a Nieman Fellowship from Harvard University for the 1988-1989 academic years. Mbeki began his journalism career in London in 1979 as a contributor to the Africa, New African, and Africa Now magazines and the BBC Africa Service. He studied Building, Building Management, and Sociology in England, obtaining an MA degree in Sociology from the University of Warwick in 1982. He worked in the construction industry in the United Kingdom and in Tanzania during the 1970s.

Pieter du Toit

Pieter du Toit is Assistant Editor at News24, where he is Head of Investigative Journalism. He was previously a crime reporter, parliamentary correspondent, and news editor at Beeld and Netwerk24. He is the author of two books – Enemy of the People, which is about state capture – and The Stellenbosch Mafia. His third book, The ANC Billionaires, will be published next month.

Dr Mareve Biljohn

Maréve IM Biljohn is a senior lecturer and Head of the Department of Public Administration and Management at the University of the Free State. She holds a Doctor of Philosophy degree in Public Administration (University of the Free State), Master of Public Administration (Stellenbosch University), BPA (Honours) Public Administration (Stellenbosch University), BAdmin (Honours) Industrial Psychology (University of the Western Cape), and BAdmin (University of the Western Cape). Prior to her appointment at the University of the Free State, she worked for a district municipality in the Western Cape, South Africa. Her research interests and expertise are in the fields of social innovation in service delivery, citizen participation in local government service delivery, and citizen participation in the governance of local government service delivery. She has presented her research at several local and international research conferences and published her research in local and international journals. Her work includes, among others, publications on:

Social innovation as an alternative approach to South African local government service delivery.
Determinants for citizen and third-sector participation during social innovation in local government service delivery.
Considerations for South African local government for using SI in open and closed governance systems.

She has also authored and co-authored book chapters, titled ‘Leading self in South Africa’s VUCA local government environment’, and ‘Social innovation to enhance service delivery by local government’

News Archive

Research contributes to improving quality of life for cancer patients

2016-11-21

Description: Inorganic Chemistry supervisors Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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