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Cervical Cancer Awareness Month: Common cancer can be prevented

27 September 2022 | Story Jóhann Thormählen | Photo iStock

Cervical cancer awareness ribbon — Cervical Cancer Awareness Month is observed in September in South Africa to encourage women to go for screening to prevent it.

Cervical cancer is the second most common cancer among women in South Africa, and many die from it each year – but it can be prevented.

According to Dr Arina Meyer, medical practitioner in Kovsie Health at the University of the Free State, this is one of the reasons why it is important to be informed, take precautions, and raise awareness about the disease.

Cervical Cancer Awareness Month is observed in September in South Africa with the aim of encouraging women to go for screening to prevent it.

Although medical statistics paint a bleak picture, Meyer says there is hope. “It is important to know that cervical cancer can be prevented. And when it is diagnosed early, it can be treated.”

Statistics and causes

According to her, figures show the occurrence of cervical cancer to be between 22,8 and 27 per 100 000 women in South Africa.

“More than 5 700 new cases are reported each year, as well as more than 3 000 deaths. Cervical cancer is the second most common cancer – after skin cancer – in South Africa.”

Meyer says when one look at these numbers, it is important to commemorate Cervical Cancer Awareness Month, as women need to be informed about their annual check-up, possible symptoms, and signs of the cancer.

Most cervical cancers are caused by the human papillomavirus (HPV), which is transmitted through sexual contact. Therefore, the HPV is seen as a sexually transmitted disease.

“There are different types of HPV. Some cause cervical cancer and other genital warts. One can develop one or both conditions, depending on the type of virus you have,” says Meyer.

Prevention and reducing the risk

According to her, preventative action is the best method. Going for a cervical screening every year when you become sexually active, such as a Pap smear or Pap test, will help in the early detection and removal of abnormal cells.

There is also a vaccine for protection against HPV, which is available from the age of nine. Meyer says there are two vaccines in South Africa.

“By getting the vaccine early, before any sexual activity, the spread of HPV – and therefore cervical cancer – can be prevented. Up to 90% of cancers can be prevented.

“Unfortunately, if someone has already been infected by the HPV, it cannot be treated by the vaccine.”

The UFS medical practitioner says the best ways to reduce the risk of cervical cancer are to go for an annual Pap smear, a follow-up after an abnormal test result, the vaccine, safe sex, and to stop smoking.

News Archive

Nanotechnology breakthrough at UFS

2010-08-19

Ph.D students, Chantel Swart and Ntsoaki Leeuw

Scientists at the University of the Free State (UFS) made an important breakthrough in the use of nanotechnology in medical and biological research. The UFS team’s research has been accepted for publication by the internationally accredited Canadian Journal of Microbiology.

The UFS study dissected yeast cells exposed to over-used cooking oil by peeling microscopically thin layers off the yeast cells through the use of nanotechnology.

The yeast cells were enlarged thousands of times to study what was going on inside the cells, whilst at the same time establishing the chemical elements the cells are composed of. This was done by making microscopically small surgical incisions into the cell walls.

This groundbreaking research opens up a host of new uses for nanotechnology, as it was the first study ever in which biological cells were surgically manipulated and at the same time elemental analysis performed through nanotechnology. According to Prof. Lodewyk Kock, head of the Division Lipid Biotechnology at the UFS, the study has far reaching implications for biological and medical research.

The research was the result of collaboration between the Department of Microbial, Biochemical and Food Biotechnology, the Department of Physics (under the leadership of Prof. Hendrik Swart) and the Centre for Microscopy (under the leadership of Prof.Pieter van Wyk).

Two Ph.D. students, Chantel Swart and Ntsoaki Leeuw, overseen by professors Kock and Van Wyk, managed to successfully prepare yeast that was exposed to over-used cooking oil (used for deep frying of food) for this first ever method of nanotechnological research.

According to Prof. Kock, a single yeast cell is approximately 5 micrometres long. “A micrometre is one millionth of a metre – in laymen’s terms, even less than the diameter of a single hair – and completely invisible to the human eye.”

Through the use of nanotechnology, the chemical composition of the surface of the yeast cells could be established by making a surgical incision into the surface. The cells could be peeled off in layers of approximately three (3) nanometres at a time to establish the effect of the oil on the yeast cell’s composition. A nanometre is one thousandth of a micrometre.

Each cell was enlarged by between 40 000 and 50 000 times. This was done by using the Department of Physics’ PHI700 Scanning Auger Nanoprobe linked to a Scanning Electron Microscope and Argon-etching. Under the guidance of Prof. Swart, Mss. Swart en Leeuw could dissect the surfaces of yeast cells exposed to over-used cooking oil.

The study noted wart like outgrowths - some only a few nanometres in diameter – on the cell surfaces. Research concluded that these outgrowths were caused by the oil. The exposure to the oil also drastically hampered the growth of the yeast cells. (See figure 1)

Researchers worldwide have warned about the over-usage of cooking oil for deep frying of food, as it can be linked to the cause of diseases like cancer. The over-usage of cooking oil in the preparation of food is therefore strictly regulated by laws worldwide.

The UFS-research doesn’t only show that over-used cooking oil is harmful to micro-organisms like yeast, but also suggests how nanotechnology can be used in biological and medical research on, amongst others, cancer cells.

Figure 1. Yeast cells exposed to over-used cooking oil. Wart like protuberances/ outgrowths (WP) is clearly visible on the surfaces of the elongated yeast cells. With the use of nanotechnology, it is possible to peel off the warts – some with a diameter of only a few nanometres – in layers only a few nanometres thick. At the same time, the 3D-structure of the warts as well as its chemical composition can be established.

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za
18 August 2010

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