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24 April 2023 | Story Anathi Nyadu and Avela Ntsongelwa | Photo Supplied
Humanities Soutpan community outreach
Collaborating to uplift the community of Soutpan. Staff members from the Faculty of the Humanities met with representatives of the Soutpan community to engage in community-enriching projects.

Universities have an important role to play in the healing of communities by engaging in initiatives that address social ills such as drug abuse, teenage pregnancy, violence against children, women, and the elderly. 

This is according to Prof Mogomme Masoga, Dean of the Faculty of the Humanities at the University of the Free State (UFS). Prof Masoga was addressing guests, including faculty staff members and community members of Soutpan, at the launch (18 April 2023) of the faculty’s community engagement partnership with the community of Ikgomotseng in Soutpan, some 40 km outside Bloemfontein.  He informed guests that the partnership was the first of many initiatives that the faculty will be engaging in with the community of Soutpan.

Flagship partnership 

The flagship partnership will see participation by various departments within the faculty, including a parenting project with carers at day-care centres and in the communities, led by students from the Department of Psychology. The Department of Drama and Theatre Arts will stimulate the children’s minds through puppet shows, while the Department of History will collaborate with the community on heritage issues. During the engagement with the community, the Department of Sociology also indicated that it is launching an engaged scholarship month project for their honours and second-year Social Movements modules, where several guest lecturers will engage with students to bring stronger social context to sociological discussion. The faculty is also exploring a literacy project where it will contribute books and inculcate a culture of reading among community members.

Talking about the origin of the collaborative engagement, Dr Rosaline Sebolao, Teaching and Learning Manager in the faculty, says “the partnership emanated from a visit by the faculty to a day-care centre called Halaletsang, founded by a community leader, Belina Nhlapo, who demonstrated her passion for empowering communities. With the intention of expanding the faculty’s engaged scholarship programme, the team entered into a number of engagements that led to the identification of potential collaborative projects by departments and the community”.

Maximum societal impact with sustainable relationships

This partnership is one way in which the Faculty of the Humanities hopes to contribute to the UFS’Vision 130. The faculty aims to bring Vision 130 to reality by conducting community research and establishing quality relationships that will yield sustainable results. These results will not only impact communities but also our students who, through their engagement, will become globally competent and competitive graduates. 

According to Israel Mawoyo, First-Year Success Programme (FYSP) coordinator in the faculty, the partnerships involve a working relationship for the Faculty of the Humanities and the community of Soutpan. “This partnership will create a platform for staff and students to engage in the scholarship of community engagement practices within the community. Ultimately, the Soutpan and the faculty community are to work together so that they both benefit from this partnership.”

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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