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05 April 2023 | Story André Damons and Samkelo Fetile | Photo istock
Union Building Pretoria
The University of the Free State presented its first webinar titled, The threats to South Africa’s domestic stability and security challenges, which is part of the 2023 Thought-Leader Webinar Series on Tuesday 4 April.

The biggest threat to South Africa’s domestic stability and the health of the country’s democracy is its leadership and the continuing political corruption of the ANC.

This is according to the panelists at the University of the Free State (UFS) first Thought-Leader webinar for the year. The webinar titled, The threats to South Africa’s domestic stability and security challenges, had as panelists Busisiwe Mavuso, Chief Executive Officer: Business Leadership South Africa; Palesa Morudu, Director: Strategy and Marketing Clarity Global Strategic Communications; Prof Hussein Solomon, Senior Professor: Centre for Gender and Africa Studies, UFS; and Dr Ivor Chipkin, Co-Founder and Director: New South Institute. Prof Francis Petersen, UFS Rector and Vice-Chancellor was the facilitator. 

Lawlessness is the problem

Mavuso said the essence of the country’s problems is lawlessness. 

“The conversation is not just about threats, but when you look at why these threats exist, it’s because we have a lawlessness problem as a country. South Africa has degenerated into a lawless country. And lawlessness is the symptom. If you want to get to the bottom of why we have a lawlessness problem, my view is that we need to start with the root – the culture issue.

“South Africa’s problem when it comes to corruption, is a culture problem. It is a culture that has been cultivated and set from the top. The political culture in South Africa is that being accused of a crime is not embarrassing. We have a culture conducive to theft, and if that is the culture at the top, what makes you think that as a country people won’t follow suit because the message is clear that crime pays and that nothing will happen to you and you can still hold political office. Better still, you can be the president of the country,” said Mavuso. 

According to her, the Global Initiative Against Transnational Organised Crime report last year shows that SA is witnessing a dramatic expansion and legitimisation of organised crime which is rising rapidly, with dire implications for the economy and the country’s stability.

Mavuso said countries fall apart when governance fails at government level because it is governments that set countries apart, not geography. Government is what separates good prosperous states from bad failing states. And it is unfortunately where we are as a country because our leaders are not what they ought to be. 

The focus for the country right now, said Mavuso, needs to be economic recovery, trying to attract investment as it is the only way to get out of this economic rut and deal with poverty, unemployment, and inequality crises.  

“I am worried that if we do not get this right, domestic stability is not going to get better. The threat to South Africa is bigger than we comprehend. It really is an issue of leadership. The solution is having the right leadership that is going to set the right tone. Let us agree and accept that South Africa is divorced from leadership which is why we are on the verge of becoming another failed African state.”

Not unique to South Africa

In her presentation, Morudu also focused on international policy and to what extent it may or not lead to negative developments on the domestic front. She said the topic is not unique to SA as the world is going through a deeply unsettling phase. From the threats to democracy, to climate change, to rising inequality, a bloody war in Ukraine, threatening economic recession as a result of COVID-19, and a growing mental health crisis among young people, especially in the US. 

“The world is quite a frightening place at the moment. I am not saying this to say that our problems are minor, but to help us understand the international context and that if we do not respond with some speed to our present challenges, not only will our backsliding economy and politics have very serious consequences for us, but it will also have major consequences for the part we play in the international system.

“I think it makes absolutely no sense for South Africa to align with Moscow over the conflict in Ukraine. Russia invaded a sovereign country; it came into that country with tanks and guns. It is very much like when the apartheid government invaded Angola in 1975 and pretty much stayed there until 1988,” said Morudu. 

According to her, South Africa’s backsliding democratic principles and foreign policy will also find expression in domestic policy. Nothing demonstrated this as keenly as the years of state capture that we lived through over the past 10 to 15 years. State institutions were hollowed out and rendered ineffective. Says Morudu: “The corruption of institutions took hold and thieves inside the state stole with impunity. The end result of that was there for all the world to see during the mass riots of July 2021. The state was literally unable to secure the safety of its own citizens. People had to organise themselves to stop the looting and to provide basic services to one another. It was an extraordinary moment for South Africa.”

Crises of democracy and the crisis of government 

Dr Chipkin said there seems to be a strong correlation in the crises of democracy in South Africa and the crisis of government. “There are questions around the role, integrity or value of democracy and I think a lot of that has to do with the crisis of government, the seeming inability of our public service, our state institutions, to deliver on the very ambitious programme of economic transformation that is part of constitutional promise.”

He said there has been a lot of work done to professionalise the public service in SA. “It is credible, intelligent, durable and I do believe that there is some appetite for change. There is an opportunity for the university to jump into that space, as activists or as academics, to claim and widen that space going forward.”

He believes that reforming the public service is going to close the door or at least narrow a pathway to the kind of corruption we have in SA. “As we make improvements in professionalising public services, I suspect organised crime is going to grow as it will be threatened by these progressive initiatives. It is going to resist. What is pertinent on the agenda is progressive moves towards modernisation in SA need to be accompanied by serious moves to reform and improve the capacity of the police to respond to the situation of interpersonal emergencies of organised crime in particular, and ultimately state capture.”

According to him, the situation [with the police] is not as dire as we think. He said the police as an institution is probably in a better state than we would like to think. “It is not full of incompetent policemen. I think it is full of a thousand capable, committed, honest and sincere policemen trying to do their jobs under circumstances which are terrifying difficult. I think challenges in the police are rather institutional.”   

Corporate sector reeling from criminal violence

Prof Solomon said the country’s security situation is rapidly deteriorating and he fears something really bad is lurking on the horizon for the country and its people. “Consider the following. It is estimated that more than 40% of women in South Africa will be raped in their lifetimes and that only one in nine rapes are reported. It is also estimated that only 14% of perpetrators of rapes are convicted in South Africa,” he said.

He stressed that beyond the level of personal violence, the corporate sector is also reeling from criminal violence. According to him, in 2019 already, 183 infrastructure and construction projects nationwide valued at more than R63 billion have been hindered by violent disruptions by the so-called construction mafia who euphemistically refer to themselves as business forums, typically demanding a 30% stake in projects.

“There has been little to no police intervention to stop this extortion economy and foreign investors flee in the face of the naked violence. As every first-year political science student knows, one of the characteristics of the state is its monopoly over coercive force within its territorial boundaries. The existence of these construction mafias and their ability to exert violence undermines this statehood, therefore South Africa is increasingly being referred to as a failed state.” 

He says this inaction begs the question as to what the state of our security services is. For 20 years terrorist financing in SA has been an issue. In July 2022 the problem of terrorism financing came to the fore when the United Nations Security Council experienced grave concern at how the Islamic State’s tentacles were spreading across the African continent and how SA has been used to fund Islamic State affiliates. 

“The bottom line is this. South Africa’s security situation is worsening. There are concrete recommendations which we can embark upon, but these will not work whilst the ANC is in power. The government lacks the capacity and legitimacy to rein in the forces of chaos which are about to envelop the country,” he said.

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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