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20 April 2023 | Story Nonsindiso Qwabe | Photo Supplied
Simphiwe Kunene revelling in the moment during the April 2023 graduations.

“The University of the Free State has given me more than just a degree; it has given me skills, attributes, and so much more, but above all else, the university gave me an opportunity.”

This is according to former Qwaqwa Campus SRC member Simphiwe Kunene, who walked across the stage to receive his Bachelor of Education in Intermediate Phase Teaching during the April 2023 graduations on the Qwaqwa Campus.

Support enabled Kunene to juggle multiple roles

Kunene, who has been involved in student life since his first year, said the support received from various individuals and structures at the UFS enabled him to juggle his multiple roles successfully, and groomed the sharp leader he considers himself to be today. As a first-generation student from the rural town of Nquthu in KwaZulu-Natal, Kunene said he “never imagined some of the achievements and support I received from the university. My journey may have been uneasy, but it has also been filled with many beautiful memories and significant moments. My life has been one of many firsts, and so I want to create many others like me."

While pursuing his studies, Kunene was a tutor and a residence assistant, and held positions in the CSRC and ISRC. “My story, like many others before me, has been riddled with challenges and adversities that sought to deter me from completing my studies. Relocating to a new environment is always difficult, and studying there is even more challenging. The challenges have been bigger, but the support from the university was way bigger. The dream has always been bigger.”

His most memorable moments are being elected as ISRC Secretary General and winning an A-Step award for best tutor in the Faculty of Education. “From a very young age, I've always wanted to change the world in one way or another. I figured that perhaps one way to do that was to be a teacher, and the Qwaqwa Campus offered me the platform to help me realise that dream of mine.”
With this degree, Kunene hopes to impact the lives of his learners just like the warm embrace of education has impacted him. 
“I am convinced that this degree – which is the first in my family – will drive out the scourge of poverty and restore dignity to the community, myself, and my family. For me, education is supposed to transform the lives of those it touches. I am a teacher, and that's my calling. My mission is to transform lives. I want to make education fashionable. This degree is the very foundation on which this premise is built.”

Driving quality, impact, and care 

He is now pursuing an honours degree with specialisation in Management and Governance in the Faculty of Education and is working as a facilitator in the Centre for Teaching and Learning. “I will forever be grateful for the support and opportunities afforded to me by this great university. I can say without fear of contradiction that lives have been changed with quality, impact, and care.”

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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