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01 August 2023 | Story NONSINDISO QWABE | Photo SUPPLIED
Apartheid Studies, A Manifesto Book Launch
Prof Nyasha Mboti launched his book, Apartheid Studies: A Manifesto, on the UFS Qwaqwa Campus on 25 July 2023.

in a perpetual state of disaster and creating a normalised life, even if it is built on anomalous arrangements, Prof Nyasha Mboti launched his newly published book, Apartheid Studies: A Manifesto, on the UFS Qwaqwa Campus on 25 July 2023.

Prof Mboti is an Associate Professor and Head of the Department of Communication Science at the University of the Free State and is the pioneer and founder of Apartheid Studies, a new interdisciplinary field of study from the Global South, which utilises the notion of ‘apartheid’ as a paradigm by which to understand the confounding persistence and permanence of harm, oppression, and injustice.

Oppressive systems persist in modern South Africa

Making reference to the pass laws that were a dominant form/tool of oppression and segregation during the country’s apartheid system, he said apartheid created a “paradigm of life where things that aren’t supposed to go on, go on. 
Life has to go on even in oppression. People have the capacity to live with harm, and apartheid banks on people’s capacity to go on”.

The daring book posits itself as a first-of-its-kind authoritative study of the phenomenon of apartheid, shedding light on the continuing impact of apartheid decades after its formal abolishment and exploring the idea that while it was intended as a temporary phenomenon, it became deeply ingrained and normalised, persisting in various forms today.

“What apartheid is, is a temporary phenomenon that has become permanent. That is my argument. This book is an attempt to leverage how we live with harm as a way of doing something about it and hopefully putting an end to it. If you can go on one day living in harm and the next, before you know it, four decades of living under Apartheid from day to day have passed. Until we understand it, it persists,” he said.

By asking whether one would queue for a dompas, Prof Mboti challenged the audience to reflect on how oppressive systems persist when normalised, even when inflicting profound harm. 
“Would you queue for a dompas? If your answer is yes, then for me, that is an indication that Apartheid persists. Harm persists. Until we understand it, it persists.”

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Cardiology Unit involved in evaluation of drug for rare genetic disease
2013-01-04

Front from the left, are: Marinda Karsten (study coordinator and registered nurse),
Laumarie de Wet (clinical technologist), Charmaine Krahenbuhl (study coordinator and radiographer),
Lorinda de Meyer (administrator), Andonia Page (study coordinator and enrolled nurse);
back Dr Gideon Visagie (sub investigator), Dr Derick Aucamp (sub investigagtor),
Prof. Hennie Theron, (principal investigator) and Dr Wilhelm Herbst (sub investigator).
Photo: Supplied
09 January 2013


The Cardiology Research Unit at the University of the Free State (UFS) contributed largely to the evaluation of the drug Juxtapid (lomitapide), which was developed by the Aegerion pharmaceutical company and approved by the FDA (Federal Drug Administration). Together with countries such as die USA, Canada and Italy, the UFS’ Unit recruited and evaluated the most patients (5 of 29) for the study since 2008.  

The drug was evaluated in persons with so-called familial homozygous hypercholesterolemia (HoFH).  

Following its approval by the FDA, Juxtapid is now a new treatment option for patients suffering from HoFH. The drug operates in a unique way which brings about dramatic improvements in cholesterol counts.  

According to Prof. Hennie Theron, Associate Professor in the Department of Cardiology at the UFS and Head of the Cardiology Contract Research Unit, HoFH is a serious, rare genetic disease which affects the function of the receptor responsible for the removal of low-density lipoprotein cholesterol (LDL-C) (“bad” cholesterol) from the body. Damage to the LDL receptor function leads to extremely high levels of blood cholesterol. HoFH patients often develop premature and progressive atherosclerosis, which is a narrowing or blockage of the arteries.  

“HoFH is a genetically transmitted disease and the most severe form of hypercholesterolemia. Patients often need a coronary artery bypass or/and aortic valve replacement before the age of 20. Mortality is extremely high and death often occurs before the third decade of life. Existing conventional cholesterol-lowering medication is unsuccessful in achieving normal target cholesterol values in this group of patients.  

“The only modality for treatment is plasmapheresis (similar to dialysis in patients with renal failure). Even with this type of therapy the results are relatively unsatisfactory because it is very expensive and the plasmapheresis has to be performed on a regular basis.  

“The drug Juxtapid, as currently evaluated, has led to a dramatic reduction in cholesterol values and normal values were achieved in several people. No existing drug is nearly as effective.  

“The drug represents a breakthrough in the treatment of familial homozygous hypercholesterolemia. The fact that it has been approved by the FDA, gives further impetus to the findings,” says Prof. Theron.  

In future further evaluation will be performed in other forms of hypocholesterolemia.  

According to Prof. Theron, the findings of the study, as well as the recent successful FDA evaluation, once again confirms the fact that the UFS’ Cardiology Contract Research Unit is doing outstanding work.  

Since its inception in 1992, the Unit has already been involved in more than 60 multi-centre, international phase 2 and 3 drug studies. Several of these studies, including the abovementioned study, really affected the way in which cardiology functions.  

The UFS’ Cardiology Contract Research Unit is being recognised nationally and internationally for its high quality of work and is constantly approached for their involvement in new studies.  

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