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07 December 2023 | Story Leonie Bolleurs | Photo CHARL DEVENISH
Dr Marié Herbst
Dr Marié Herbst received her PhD with specialisation in Design, titled The (S)Pace of Images: establishing a practice of the conscious abstraction of motion. She hopes that the techniques and processes explored in her research will spark creativity in the way other designers approach their work.

“My research has unveiled the exquisite patterns generated by motion in nature and everyday objects – patterns that often evade our awareness as we encounter motion in a fleeting moment. Abstraction plays a pivotal role in unveiling these exquisite yet largely unnoticed patterns that surround us.”

This is the perspective of Dr Marié Herbst, who graduated at the University of the Free State (UFS) in December, receiving her PhD with specialisation in Design, titled The (S)Pace of Images: establishing a practice of the conscious abstraction of motion.

Abstraction, a key component of building design

Dr Herbst says that the abstract art movement has had a profound influence on how designers think about design. “Highly regarded architects such as Le Corbusier and Zaha Hadid identify their practice of creating abstract paintings as the driving force behind their ground-breaking building designs. Abstraction is therefore a key component of building design, although the process of how it is applied has historically not received adequate attention. My research explores the way abstraction enables designers to include design information that is only possible through the process of abstraction. One such aspect is motion. Through the process of tracing and superimposing still images extracted from films, I can integrate them into a single picture that shows the progression of time,” she explains.

She hopes that the techniques and processes explored in her research will ignite creativity in how other designers approach their work. “The concepts and techniques outlined in my research are intended to prompt other designers to reconsider the procedures they employ when crafting spaces,” she states.

In the future, Dr Herbst says, she would like to further explore the ideas sparked by her research, such as determining how design would be affected by recording movement in a three-dimensional environment. “New technologies such as LiDAR make the recording of three-dimensional information much simpler, and it will increasingly become a part of our everyday lives. This is a potentially useful information stream that could be applied to create novel designs,” she says.

‘Practice-based’ versus ‘design-led’ research

Prof Jonathan Noble, Head of the Department of Architecture, says this is the very first PhD from the new creative research programme in architecture that was launched in 2018, where the student has completed a ‘design-led’ enquiry. 

He explains that the new creative programme differentiates between ‘practice-based’ research, closely tied to real-world architecture, where candidates analyse and study their previous work, and ‘design-led’ research, which is led by an entirely new creative exploration that encourage speculation and experimentation. According to him, the latter leads to a creative enquiry, and this body of new work is analysed and written about.

Following Prof Noble, postgraduate research in architecture in South Africa has traditionally centred around architectural theory, cultural history, urban studies, and conservation. Creative research methods, however, have not been as prominent. The Department of Architecture is addressing this by introducing new postgraduate research modes supported by innovative research degrees, marking a departure from the traditional approach in South Africa.

“We believe the programme will have a lasting and significant effect upon our professional degrees, injecting professional creativity and new thinking into the life of the department, and serving as an opportunity to look deeply into design and pedagogic practices. Over time, the programme will strengthen ties with the profession and address the closed mentalities of the so-called ‘academic ivory tower’.”

“In addition to providing emerging young scholars with opportunities, the programme facilitates the documentation of the unique qualities of South African practice and makes an important contribution to future research publication and teaching pedagogy at the UFS and beyond,” he says.

News Archive

Collaboration between UFS and Mayo Clinic to revolutionise cancer treatment
2014-06-27



Attending the lecture were, from the left: Dr Chantel Swart, Prof Lodewyk Kock, Prof Debabrata Mukhopadhyay, Prof James du Preez; back: Prof Pieter van Wyk.
Dr Swart, Profs Kock and Du Preez are from the Department of Microbial, Biochemical and Food Biotechnology. Prof Mukhopadhyay is from the Mayo Clinic (US) and Prof Van Wyk is from the Centre for Microscopy at the UFS.
Photo: Supplied
The UFS made a discovery that may have enormous implications for the treatment of diseases in humans.

Since the discovery, the UFS joined forces with the Mayo Clinic in Rochester, US, in the fight against cancer.

In this collective effort, UFS researchers would be able to assist the Mayo team to:
• see how treatment in cancer patients is progressing,
• target treatments more effectively,
• reduce dosages in order to make treatment gentler on the patient,
• track the effectiveness of the chemotherapy drugs used, and
• gain an accurate view of how the cancer is being eliminated.

Prof Lodewyk Kock, Outstanding Professor at the Department of Microbial, Biochemical and Food Biotechnology, and his team incidentally created a technique to use argon gas particles for the first time on biological material to slice open cells to look inside.

The team that supported Prof Kock includes Dr Chantel Swart, Khumisho Dithebe (PhD student), Prof Hendrik Swart (Department of Physics) and Prof Pieter van Wyk (Centre for Microscopy).

Prof Debabrata Mukhopadhyay from the Mayo Clinic in Rochester, US, got to hear about this breakthrough at the UFS and a collaboration between the two institutions was established.

During a visit to the Bloemfontein Campus, Prof Mukhopadhyay explained novel techniques that make use of gold nanoparticles. These particles attach to chemotherapeutic drugs to selectively target cancer cells – dramatically decreasing the side effects to normal human cells.

For these new drugs (coupled to gold nanoparticles) to be accepted into clinical practice, visual and chemical proof is needed, though. This is where the technique developed by the UFS will play a vital role.

With the technique to look inside cells, the composition, location and metabolism of these drugs can be determined. This will aid in a proof of concept for the application of the nano-drugs. Furthermore, it will enable approval for use of these drugs in clinical trials and eventually could revolutionise cancer treatment as a whole.

For video lectures on the technique used, as well as its findings, follow these links:

1. http://vimeo.com/63643628 (Comic version for school kids)

2. http://vimeo.com/61521401 (Detailed version for fellow scientists)

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