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13 December 2023 | Story André Damons | Photo Charl Devenish
Dr Shezree Tiel
Top student: Dr Shezree Tiel graduated top of her class and summa cum laude during the Faculty of Health Sciences graduation ceremony on Friday.

As she achieved the goals she had set for herself, Dr Shezree Tiel, one of the latest graduates from the University of the Free State (UFS) Faculty of Health Sciences (FoHS), developed the courage to not only define her goals, but aim for even more. This is the reason she graduated not only summa cum laude, but as the top student in her year group.

Dr Tiel was one of 459 students who graduated on Friday (8 December 2023) during the FoHS’s December graduation ceremony. She graduated with a MBChB degree and is one of eight students to do so summa cum laude. During her five years of studies to become a medical doctor, she was the top student in each of her year groups.  

“I feel very excited and still in disbelief, because it has been my dream since first year to graduate cum laude, but there were moments I felt I may have to accept that it may not be possible. So, I am very delighted that despite all the challenges I faced, my dream was realised,” she said.

According to her, she decided to study at UFS as it is the only university in South Africa that offered a five-year medical degree.

Building healthier and happier communities

Talking about how she achieved this, Dr Tiel, who will be doing her community service year in her home province of Mpumalanga, said what was consistent throughout her years of study, was the need to avoid a uniform approach to studying. Instead, she continued, she embraced different ways to learn.

Said Dr Tiel: “I embraced different ways to acquire knowledge and used these to identify a method of study that would be best suited for each module, chapter and sometimes each day. Everyday courage, resilience, patience, and perseverance played a vital role in accomplishing all my achievements. In spite of all of this, I will always attribute my achievements to my trust in Christ.”

Her desire to make the best possible use of every opportunity she gets to gain knowledge and the hope to use that knowledge to be useful to people and communities, motivated her on her journey to become a doctor. She decided to study medicine because she aspired to work with people in the pursuit of building healthier and happier communities. She believed that medicine would provide a great foundation and platform to accomplish this.

Though she is yet to decide in which field she would like to specialise one day, she believes it would be in internal medicine because it has always been one of her favourite rotations. “I do hope whichever one I go into will provide me with an opportunity to teach because that is one of the things I delight in.”

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Dr Charlotte Boucher and Lindi Heyns examine possible anti-microbial activity in the skin of Western olive toad species
2014-12-22

 

Researchers Lindi Heyns and Dr Charlotte Boucher are working together on an interdisciplinary project between the Departments of Zoology and Entomology and Veterinary Biotechnology at the University of the Free State (UFS). The focus of their research is on the preliminary biochemical description of skin secretions in some South African toads.

The project forms part of an Honours study executed by Dwayne Pike under Heyns’ supervision. He is co-supervised by Dr Boucher who is assisting with the biochemical and microbiological assays.

Dr Boucher said, “Amphibians are characterised by the presence of cutaneous glands spread over the skin. There are two types of glands, namely mucous and granular (poison), located on the inner surface of the epidermis. Mucous glands are widely dispersed over the skin, while granular glands can be grouped and enlarged in specific regions. Mucous glands are generally associated with maintenance of humidity and cutaneous respiration, whereas granular glands function in chemical defence against predators and/or microbial infection. Studies indicate that the compounds produced by the granular glands belong to numerous chemical classes with diverse pharmacological activities.”

The products secreted by granular glands are rich in low molecular weight constituents of varied molecular types, including proteins, peptides and toxins. These secretions make the toad foul-tasting to predators and even toxic to other frog species. In addition, amphibians offer an attractive source of novel antimicrobials. Studies indicate that as a response to inhabiting microorganism-rich environments they synthesise and secrete a diverse array of antimicrobial peptides (AMPs) as an innate form of defence. Extensive research by various other research groups has been carried out on antimicrobial peptides of the genus Rana; however, hardly any studies have investigated the antimicrobial activity of African frog species.

The focus of this preliminary project is to determine the protein composition of the glandular secretions of the Western olive toad (Amietophrynus poweri), using biochemical tests, such as SDS-PAGE also known as protein gel electrophoresis combined with mass-spectrometry used to identify unknown peptides and proteins. This will give us an overview of the composition of the glandular secretions. Furthermore, we are also looking at microbiological tests, which include assays that test for possible anti-microbial activity against various bacterial and fungal species.

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