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07 December 2023 | Story Leonie Bolleurs | Photo Charl Devenish
Six from Natural and Agricultural Sciences receive PhDs at December graduations
Six academics in the Faculty of Natural and Agricultural Sciences walked across the stage in the Callie Human Centre to receive their much-deserved PhD qualifications. Pictured are, from the left: Dr Bennie Botha, Dr Lindie von Maltitz, Dr Leon Kruger, Dr Anathi Makamane, Dr Megan Welman Purchase, and Dr Marike Stander.

Today, after years of hard work, a group of PhD graduates in the Faculty of Natural and Agricultural Sciences at the University of the Free State (UFS) stepped onto the stage in the Callie Human Centre with a sense of accomplishment and excitement to receive their doctoral degrees. The graduates covered an array of topics in their studies – from the use of virtual reality in health-care education to the well-being of sheep. 

Avoiding cybersickness

Dr Bennie Botha, Lecturer in the Department of Computer Science and Informatics, created a framework for use in immersive virtual clinical simulations by virtual reality users (students), software developers, researchers, and educators. According to him, this can help to avoid cybersickness – much the same as motion sickness – a condition that can occur when an individual's perception of motion conflicts with their visual senses.

“The result is a more inclusive immersive virtual reality experience for students who would otherwise not be able to engage with this technology and reap the benefits it can bring to their education,” says Dr Botha, who wants to establish a global footprint and advance the use of all types of virtual reality in an African context.

He submitted his thesis: A framework to prevent or minimise cybersickness during immersive virtual clinical simulation.

Agricultural extensionists of the future

Dr Lindie von Maltitz, Lecturer in the Department of Agricultural Economics, conducted two studies in her research. The first was to determine the crucial skills and competencies that agricultural extensionists need in their modern-day workplace. The second focused on the available undergraduate curricula offered in South Africa, which fail to address these critical skills and competencies. She found a list of skills and professional competencies that are not sufficiently covered in the available curricula, and some are lacking entirely.

In the last chapter of her thesis, Skills and competencies of agricultural extension professionals in South Africa: implications for higher education curricula, Dr Von Maltitz provides recommendations on what to include in curricula at higher education institutions that will equip the agricultural extensionists of the future to excel in their profession and contribute to agricultural development. “I am excited to contribute more to curriculum development, especially in the field of agriculture in general. Farming with my husband for the past 20 years has allowed me to obtain first-hand experience in farming and agri-business. I have walked the road, and I am still walking it. I teach by bringing theory into context with real-life situations that I have personally experienced,” she states.

The well-being of sheep

Society often questions how we treat the animals we eat. Dr Leon Kruger, Lecturer in the Department of Animal Science, delves into this question through his research, titled: The effect of temperament and stress on production and immune response in sheep. His study explores, among others, the impact of short-term stress on production performance in sheep, the effect of stress on immune response post-vaccination, and the relationship between a sheep's temperament and stress.

“The focus is not just on doing what's perceived as best for the animals, but on applying practices that limit stress. We so often hear of marketing slogans such as grass-fed or grain-fed or Karoo lamb. Just imagine how the consumer would appreciate a slogan such as stress-free reared. It is not that far-fetched,” he believes.

Dr Kruger’s future research plans include investigating stressor effects associated with livestock auctions, examining the entire process from loading on the farm to unloading on the new farm. “I also want to compile a species vocabulary, analysing specific sounds that animals make in different situations. I want to describe the sound of an animal and link it to a situation, for example, the sound a ewe makes shortly after she lambs,” he says.

Adapting to climate change

Dr Anathi Makamane, Junior Lecturer in the Department of Sustainable Food Systems and Development, says the realisation that her research findings have spurred a tangible project aimed at increasing the capabilities of extension workers is immensely fulfilling. “Being part of a community dedicated to sustainable agriculture and witnessing the transformative impact of research outputs underscores the profound satisfaction derived from this journey,” she states.

Her thesis, Capacity of extension and advisory services in supporting farmers to adapt to climate change in the Eastern Cape, South Africa, sheds light on the critical role that extension workers play in assisting farmers with climate change adaptation. “My research outputs have translated into a practical project that aims to enhance the capacity of extension workers, ensuring that they possess the requisite skills to support farmers effectively,” explains Dr Makamane.

“Looking forward, my future goals involve the continued pursuit of research that directly contributes to the betterment of agricultural practices. Beyond this, I aim to engage in broader conversations on sustainable agriculture, collaborating with stakeholders to advocate for evidence-based policies that can benefit farmers nationwide,” she adds.

Managing potential environmental risks

With her PhD, Dr Megan Welman Purchase, Scientific Officer in the Department of Geology, explored the stability of iron-cyanide minerals found in the waste material of gold mines, commonly known as gold mine dumps or tailings facilities. The title of her thesis is: An investigation of the iron-cyanide mineralisation in gold mine dumps.

She says the implications of her work are of great significance for society. “Understanding the stability of iron-cyanide minerals helps in assessing and managing potential environmental risks associated with gold mine dumps. Moreover, the revelation that natural microbes can play a role in remediating cyanide contamination suggests a more sustainable and eco-friendly approach to addressing environmental concerns related to mining activities. This has the potential to positively impact both the environment and communities near mining sites,” Dr Welman Purchase explains. 

The article has been cited by international authors at least three times since its publication, demonstrating its value to a global audience.

In future steps, Dr Welman Purchase would like to delve deeper into and understand these gold mine tailings facilities. “Additionally, I plan to investigate the specific conditions under which these natural remediation mechanisms are most effective, paving the way for practical and scalable applications in mining and environmental management,” she states, excited to be involved in science that can make a difference.

Improving soil erosion conservation efforts

With her thesis, Dr Marike Stander, Lecturer in the Department of Geography, delved into the intricacies of soil erosion with her research. Concentrating on a catchment in the Eastern Free State renowned for erodible soils, her analysis of sediments unravelled their origins.

Highlighting the far-reaching consequences, Dr Stander says that “soil erosion has detrimental effects on agricultural productivity by degrading arable land quality, but also that sedimentation in water bodies diminishes reservoir storage capacity with a myriad of adverse effects on aquatic environments”. She adds that a profound understanding of soil erosion processes, coupled with identifying and quantifying sediment sources, can pinpoint conservation efforts. “For agricultural land, it means sustaining productivity and food security, and for water resources, it holds value in planning reservoir placement, optimising water storage and ensuring healthy aquatic environments,” she explains.

In line with global initiatives, she adds, “Healthy soils play a pivotal role in achieving many of the United Nations’ sustainable development goals (SDG), since it links to safeguarding terrestrial ecosystems, reversing land degradation, and promoting sustainable agriculture, to name but a few.”

“It is rewarding to contribute to the often-overlooked global environmental issue of soil erosion. The potential to make even a slight impact on the environment and society is meaningful and fulfilling,” she says.

News Archive

Inaugural lecture: Prof Robert Bragg, Dept. of Microbial, Biochemical and Food Biotechnology
2006-05-17



Attending the inaugural lecture were in front from the left Prof Robert Bragg (lecturer at the Department of Microbial, Biochemical and Food Biotechnology) and Frederick Fourie (Rector and Vice-Chancellor).  At the back from the left were Prof James du Preez (Departmental Chairperson:  Department of Microbial, Biochemical and Food Biotechnology) and Prof Herman van Schalkwyk (Dean: Faculty of Natural and Agricultural Sciences). Photo: Stephen Collett
 

A summary of an inaugural lecture delivered by Prof Robert Bragg at the University of the Free State:

CONTROL OF INFECTIOUS AVIAN DISEASES – LESSONS FOR MAN?

Prof Robert R Bragg
Department of Microbial, Biochemical and Food Biotechnology
University of the Free State

“Many of the lessons learnt in disease control in poultry will have application on human medicine,” said Prof Robert Bragg, lecturer at the University of the Free State’s (UFS) Department of Microbial, Biochemical and Food Biotechnology during his inaugural lecture.

Prof Bragg said the development of vaccines remains the main stay of disease control in humans as well as in avian species.  Disease control can not rely on vaccination alone and other disease-control options must be examined.  

“With the increasing problems of antibiotic resistance, the use of disinfection and bio security are becoming more important,” he said.

“Avian influenza (AI) is an example of a disease which can spread from birds to humans.  Hopefully this virus will not develop human to human transmission,” said Prof Bragg.

According to Prof Bragg, South Africa is not on the migration route of water birds, which are the main transmitters of AI.  “This makes South Africa one of the countries less likely to get the disease,” he said.

If the AI virus does develop human to human transmission, it could make the 1918 flu pandemic pale into insignificance.  During the 1918 flu pandemic, the virus had a mortality rate of only 3%, yet more than 50 million people died.

Although the AI virus has not developed human-to-human transmission, all human cases have been related to direct contact with infected birds. The mortality rate in humans who have contracted this virus is 67%.

“Apart from the obvious fears for the human population, this virus is a very serious poultry pathogen and can cause 100% mortality in poultry populations.  Poultry meat and egg production is the staple protein source in most countries around the world. The virus is currently devastating the poultry industry world-wide,” said Prof Bragg.

Prof Bragg’s research activities on avian diseases started off with the investigation of diseases in poultry.  “The average life cycle of a broiler chicken is 42 days.  After this short time, they are slaughtered.  As a result of the short generation time in poultry, one can observe changes in microbial populations as a result of the use of vaccines, antibiotics and disinfectants,” said Prof Bragg.   

“Much of my research effort has been directed towards the control of infectious coryza in layers, which is caused by the bacterium Avibacterium paragallinarum.  This disease is a type of sinusitis in the layer chickens and can cause a drop in egg product of up to 40%,” said Prof Bragg.

The vaccines used around the world in an attempt to control this disease are all inactivated vaccines. One of the most important points is the selection of the correct strains of the bacterium to use in the vaccine.

Prof Bragg established that in South Africa, there are four different serovars of the bacterium and one of these, the serovar C-3 strain, was believed to be unique to Southern Africa. He also recently discovered this serovar for the first time in Israel, thus indicating that this serovar might have a wider distribution than originally believed.

Vaccines used in this country did not contain this serovar.  Prof Bragg established that the long term use of vaccines not containing the local South African strain resulted in a shift in the population distribution of the pathogen.

Prof Bragg’s research activities also include disease control in parrots and pigeons.   “One of the main research projects in my group is on the disease in parrots caused by the circovirus Beak and Feather Disease virus. This virus causes serious problems in the parrot breeding industry in this country. This virus is also threatening the highly endangered and endemic Cape Parrot,” said Prof Bragg.

Prof Bragg’s research group is currently working on the development of a DNA vaccine which will assist in the control of the disease, not only in the parrot breeding industry, but also to help the highly endangered Cape Parrot in its battle for survival.

“Not all of our research efforts are directed towards infectious coryza or the Beak and Feather Disease virus.  One of my Masters students is currently investigating the cell receptors involved in the binding of Newcastle Disease virus to cancerous cells and normal cells of humans. This work will also eventually lead to a possible treatment of cancer in humans and will assist with the development of a recombinant vaccine for Newcastle disease virus,” said Prof Bragg.

We are also currently investigating an “unknown” virus which causes disease problems in poultry in the Western Cape,” said Prof Bragg.
 
“Although disinfection has been extensively used in the poultry industry, it has only been done at the pre-placement stage. In other words, disinfectants are used before the birds are placed into the house. Once the birds are placed, all use of disinfectants stops,” said Prof Bragg.

“Disinfection and bio security can be seen as the ‘Cinderella’ of disease control in poultry.  This is also true for human medicine. One just has to look at the high numbers of people who die from hospital-acquired infections to realise that disinfection is not a concept which is really clear in human health care,” said Prof Bragg.

Much research has been done in the control of diseases through vaccination and through the use of antibiotics. “These pillars of disease control are, however, starting to crumble and more effort is needed on disinfection and bio security,” said Prof Bragg.

Prof Bragg has been working in close co-operation with a chemical manufacturing company in Stellenbosch to develop a unique disinfectant which his highly effective yet not toxic to the birds.

As a result of this unique product, he has developed the continual disinfection program for use in poultry. In this program the disinfectant is used throughout the production cycle of the birds. It is also used to ensure that there is excellent pre-placement disinfection.

“The program is extensively used for the control of infectious diseases in the parrot-breeding industry in South Africa and the product has been registered in 15 countries around the world with registration in the USA in the final process,” said Prof Bragg.

“Although the problem of plasmid mediated resistance to disinfectants is starting to rear its ugly head, this has allowed for the opening of a new research field which my group will hopefully exploit in the near future,” he said.

 

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