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UFS doctoral candidate triumphs in National 3 Minute Thesis Competition with revolutionary Infant Virome Research

04 December 2023 | Story LUNGA LUTHULI | Photo SUPPLIED

Milton Mogotsi, a PhD student at the University of the Free State (UFS), has secured a remarkable victory in the esteemed National 3 Minute Thesis competition (3MT), rising above formidable competition nationwide. This achievement follows Mogotsi’s earlier successes at faculty and institutional levels, where his presentations on the enteric virome of infants in the Free State stood out for their brilliance and significance.

The annual competition serves as a platform for postgraduate students to enhance their academic, presentation, and research communication skills by succinctly explaining their research to an intelligent but non-specialist audience within a concise 3-minute timeframe.

Reflecting on his initial reaction to the news, Mogotsi expressed a mix of shock and excitement. “I was genuinely shocked and excited when declared the winner,” he shared. This victory marked a significant milestone for Mogotsi, as a first-time participant, showcasing the excellence of both the UFS and the Faculty of Health Sciences.

Exploring uncharted territories

Mogotsi’s groundbreaking research delves into the unexplored domain of the enteric virome in infants, a subject inspired by his earlier master’s study in microbiology. “I was first introduced to this research during my master’s degree, and compelling findings motivated me to pursue further studies,” explained Mogotsi. Guided by his mentor, Prof Martin Nyaga, Mogotsi's doctoral journey unfolded into a profound exploration of the complexities of viruses colonising infants' guts and their implications on infant health.

Sharing key findings, Mogotsi highlighted that, despite detecting several disease-causing viruses in infants’ guts, none exhibited clinical symptoms. This emphasises the role of immunity and protective measures like breastfeeding. He also identified plant viruses, potentially transmitted through the environment or food sources, raising intriguing questions about infants’ exposure.

His pioneering use of viral metagenomics in unravelling the enteric virome’s complexity underscored its potential in understanding human health and disease. “Viral metagenomics has become a fundamental tool, shedding light on the composition of the infant’s enteric virome,” explained Mogotsi.

Navigating challenges

Despite challenges, including disruptions due to COVID-19 and participant withdrawals, Mogotsi persevered, underscoring the importance of a longitudinal approach in comprehending the infant virome’s development over time. His success in the competition not only boosted his confidence but also expanded his networks, providing invaluable opportunities to present his findings internationally.

Mogotsi's advice to aspiring researchers mirrors his own journey: clarity of purpose, resilience in the face of challenges, fostering mentor relationships, and making the most of available resources. His groundbreaking work is poised to influence policy, guide vaccine strategies, and reshape our understanding of infant health.

As Mogotsi approaches the completion of his PhD, the future holds promising horizons for this trailblazing researcher, poised to leave an indelible mark on the world of virology and infant health.

News Archive

“I, too, am an African,” says visiting US drama professor

2013-03-06

Africans are of blood and of soil, says Prof Charles Dumas in his inaugural lecture at the UFS. Speaking on the topic I, too, am an African, Prof Dumas reminisced about his life and experiences on the continent.
Photo: Minette Grove
05 March 2013

Lecture (pdf)

What is an African? Is it those born in Africa, defined in racial and genealogical terms, or those who identifies with the continent in nationality and ancestral location? Did the descendants of enslaved Africans in the US, the Caribbean or Brazil lose their Africaness when their ancestors were put on slave ships to the New World?

These were some of the questions raised by Prof Charles Dumas, visiting senior professor in the Department Drama and Theatre Arts, in his inaugural lecture at the university.

Proclaiming attachment to the continent, Prof Dumas told his audience there are two types of Africans: Africans of the blood and Africans of the soil. In a speech titled, “I, too, am an African,” he stated that he lay claim to his ancestral birthright not because of blood relationship to an identifiable ethnic group or birthright to the continent, but because he earned it.

“I suggest another way that one can be an African, is through trial and struggle to be reborn an African in spirit. It is a ritual journey that may be taken by anyone. For, after all, if we are to believe the anthropologists who tell us that human life as we know it began in the Olduvai Gorge, genetically we are all African in origin.”

Prof Dumas, a senior professor at Penn State University in the USA, took the audience on a journey of his experiences on the continent, starting in 1978 when he first came to South Africa as a legal observer. Noticing the changes between Apartheid and today’s South Africa, he said this generation are committed to learn from each other – and that is the most important, he said.

“With their hopes and aspirations they earnestly desire to live in the new South Africa that we promised them. We must support them in their effort. It is time we stored our old baggage in the closet.”

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