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UFS doctoral candidate triumphs in National 3 Minute Thesis Competition with revolutionary Infant Virome Research

04 December 2023 | Story LUNGA LUTHULI | Photo SUPPLIED

Milton Mogotsi, a PhD student at the University of the Free State (UFS), has secured a remarkable victory in the esteemed National 3 Minute Thesis competition (3MT), rising above formidable competition nationwide. This achievement follows Mogotsi’s earlier successes at faculty and institutional levels, where his presentations on the enteric virome of infants in the Free State stood out for their brilliance and significance.

The annual competition serves as a platform for postgraduate students to enhance their academic, presentation, and research communication skills by succinctly explaining their research to an intelligent but non-specialist audience within a concise 3-minute timeframe.

Reflecting on his initial reaction to the news, Mogotsi expressed a mix of shock and excitement. “I was genuinely shocked and excited when declared the winner,” he shared. This victory marked a significant milestone for Mogotsi, as a first-time participant, showcasing the excellence of both the UFS and the Faculty of Health Sciences.

Exploring uncharted territories

Mogotsi’s groundbreaking research delves into the unexplored domain of the enteric virome in infants, a subject inspired by his earlier master’s study in microbiology. “I was first introduced to this research during my master’s degree, and compelling findings motivated me to pursue further studies,” explained Mogotsi. Guided by his mentor, Prof Martin Nyaga, Mogotsi's doctoral journey unfolded into a profound exploration of the complexities of viruses colonising infants' guts and their implications on infant health.

Sharing key findings, Mogotsi highlighted that, despite detecting several disease-causing viruses in infants’ guts, none exhibited clinical symptoms. This emphasises the role of immunity and protective measures like breastfeeding. He also identified plant viruses, potentially transmitted through the environment or food sources, raising intriguing questions about infants’ exposure.

His pioneering use of viral metagenomics in unravelling the enteric virome’s complexity underscored its potential in understanding human health and disease. “Viral metagenomics has become a fundamental tool, shedding light on the composition of the infant’s enteric virome,” explained Mogotsi.

Navigating challenges

Despite challenges, including disruptions due to COVID-19 and participant withdrawals, Mogotsi persevered, underscoring the importance of a longitudinal approach in comprehending the infant virome’s development over time. His success in the competition not only boosted his confidence but also expanded his networks, providing invaluable opportunities to present his findings internationally.

Mogotsi's advice to aspiring researchers mirrors his own journey: clarity of purpose, resilience in the face of challenges, fostering mentor relationships, and making the most of available resources. His groundbreaking work is poised to influence policy, guide vaccine strategies, and reshape our understanding of infant health.

As Mogotsi approaches the completion of his PhD, the future holds promising horizons for this trailblazing researcher, poised to leave an indelible mark on the world of virology and infant health.

News Archive

Is Al-Qaeda operating in South Africa?

2014-09-29

Our Department of Political Studies and Governance recently hosted a seminar with investigative journalist De Wet Potgieter – author of the book, ‘Black Widow White Widow’.During the seminar, Potgieter reflected on the research he has conducted for the book, revealing the unsettling presence of Al-Qaeda in South Africa.

The ‘White Widow’ in the book’s title refers to Samantha Lewthwaite, a British woman who was found in South Africa with a fraudulent passport. She was later linked to the Westgate shopping mall attack which took place in Nairobi, Kenya on 21 September 2013. In this mass shooting at least 67 people died and over 175 people were wounded. The Islamist group al-Shabaab – which is also linked to Al-Qaeda – claimed responsibility for the incident.

In contrast, the ‘Black Widow’ is the disclosed identity of an Afrikaans-speaking self-styled spy, who after being widowed became a counter-terrorist operative.

Potgieter’s book divulges details of Al-Qaeda paramilitary and urban warfare training on a secluded farm in the Little Karoo and reveals details of the support they receive from various local extremist groups. Potgieter’s investigation spans across two years and suggests possible future attacks from, or on, South African soil.

“South Africa plays a role in the bigger picture for Al-Qaeda Islamic terrorism,” Potgieter said. “For instance, the Navy Seal team who killed Bin Laden found reports pointing to active Al-Qaeda/Islamist presence in South Africa. South Africans need to know we are under siege by a small, well-trained Al Qaeda terrorist cell. Yet, operations – of which I know, but cannot disclose much – are also underway to contain these matters,” Potgieter added.

Potgieter’s sources suggest that Al-Qaeda has been active in South Africa since the 2010 FIFA World Cup already. The South African government seems to turn a blind eye, though, despite CIA and MI6 requests and enquiries on the matter.

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