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04 December 2023 | Story LUNGA LUTHULI | Photo SUPPLIED
Milton Mogotsi
Charting unexplored territories: Milton Mogotsi, UFS PhD student, clinches victory in National 3MT Competition, unravelling infant enteric virome complexities, poised to revolutionise virology.

Milton Mogotsi, a PhD student at the University of the Free State (UFS), has secured a remarkable victory in the esteemed National 3 Minute Thesis competition (3MT), rising above formidable competition nationwide. This achievement follows Mogotsi’s earlier successes at faculty and institutional levels, where his presentations on the enteric virome of infants in the Free State stood out for their brilliance and significance.

The annual competition serves as a platform for postgraduate students to enhance their academic, presentation, and research communication skills by succinctly explaining their research to an intelligent but non-specialist audience within a concise 3-minute timeframe.

Reflecting on his initial reaction to the news, Mogotsi expressed a mix of shock and excitement. “I was genuinely shocked and excited when declared the winner,” he shared. This victory marked a significant milestone for Mogotsi, as a first-time participant, showcasing the excellence of both the UFS and the Faculty of Health Sciences.

Exploring uncharted territories

Mogotsi’s groundbreaking research delves into the unexplored domain of the enteric virome in infants, a subject inspired by his earlier master’s study in microbiology. “I was first introduced to this research during my master’s degree, and compelling findings motivated me to pursue further studies,” explained Mogotsi. Guided by his mentor, Prof Martin Nyaga, Mogotsi's doctoral journey unfolded into a profound exploration of the complexities of viruses colonising infants' guts and their implications on infant health.

Sharing key findings, Mogotsi highlighted that, despite detecting several disease-causing viruses in infants’ guts, none exhibited clinical symptoms. This emphasises the role of immunity and protective measures like breastfeeding. He also identified plant viruses, potentially transmitted through the environment or food sources, raising intriguing questions about infants’ exposure.

His pioneering use of viral metagenomics in unravelling the enteric virome’s complexity underscored its potential in understanding human health and disease. “Viral metagenomics has become a fundamental tool, shedding light on the composition of the infant’s enteric virome,” explained Mogotsi. 

Navigating challenges

Despite challenges, including disruptions due to COVID-19 and participant withdrawals, Mogotsi persevered, underscoring the importance of a longitudinal approach in comprehending the infant virome’s development over time. His success in the competition not only boosted his confidence but also expanded his networks, providing invaluable opportunities to present his findings internationally.

Mogotsi's advice to aspiring researchers mirrors his own journey: clarity of purpose, resilience in the face of challenges, fostering mentor relationships, and making the most of available resources. His groundbreaking work is poised to influence policy, guide vaccine strategies, and reshape our understanding of infant health.

As Mogotsi approaches the completion of his PhD, the future holds promising horizons for this trailblazing researcher, poised to leave an indelible mark on the world of virology and infant health.

News Archive

Discovery in Scorpius constellation may signify clean energy for Earth
2017-01-23

 Description: Discovery in Scorpius constellation may signify clean energy for Earth Tags: Discovery in Scorpius constellation may signify clean energy for Earth

Earlier this year, a group of international astronomers
announced the discovery of an exotic binary star system,
AR Scorpii. The system is in the Scorpius constellation.
Photos: Supplied

See article on Nature’s website 

In future, stargazers and astronomers will look at the Scorpius constellation near the Milky Way with new eyes. Earlier this year, a group of international astronomers announced the discovery of an exotic binary star system, AR Scorpii. The system is in the Scorpius constellation.

Prof Pieter Meintjes, researcher in the Department of Physics at the University of the Free State (UFS), worked with four colleagues on what he describes as a “wonderful discovery”. This sensational discovery, which could lead to the production of cleaner energy on Earth, will be published in the research journal, Nature, early in 2017.

Model developed to interpret new set of measurements
The exotic binary star which was discovered consists of a red dwarf and a white dwarf revolving around each other every 3,5 hours. The binary system showed very prominent pulsations of 117 and 118 seconds respectively. The pulsations can be explained by a bundle radiation produced by the white dwarf star.

“These new observations have shown that the radiation is strongly polarised, a sign that we are dealing with synchrotron radiation here. Synchrotron radiation is produced by electrons accelerated to extremely high energy levels in the magnetic field of the white dwarf star,” says Prof Meintjes.

He developed a theoretical model to interpret a new set of measurements that was taken by the 1,9 m telescope and the 10 m SALT telescope at the South African Astronomical Observatory (SAA0).

Totally unique phenomenon could contribute to energy production on Earth
“I further indicated that the interaction between the magnetic fields of the white dwarf star and the red dwarf star induces secondary processes that specifically describe the behaviour of the radiation in the radio band and infrared band accurately. AR Sco is the first white-red dwarf binary system of which all the pulsated radiation could be explained by the synchrotron process, which is totally unique,” says Prof Meintjes.

According to Prof Meintjes, the value of the model lies in the fact that the processes which produce the radiation in AR Sco, can also be applied to produce energy on Earth.

 

Plasma reactors are based on roughly the same processes which apply in AR Sco, and with refining, it could be utilised to generate electricity in future. This will be much cleaner than nuclear energy.

 

The model developed by Prof Meintjes explains all the radiation in the system – from radio waves to X-rays – in terms of electrons accelerated to extremely high energy levels by electric fields in the system, which then produce synchrotron radiation over a very wide band of the electromagnetic spectrum.

Prof Meintjes is currently working on a follow-up article examining the evolution of the AR Sco, in other words, the origin of such a unique system and the final state towards which it is evolving. “My vision for the immediate future is therefore to develop a model for the evolution of the source concerned,” he says.

 

 

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