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04 December 2023 | Story LUNGA LUTHULI | Photo SUPPLIED
Milton Mogotsi
Charting unexplored territories: Milton Mogotsi, UFS PhD student, clinches victory in National 3MT Competition, unravelling infant enteric virome complexities, poised to revolutionise virology.

Milton Mogotsi, a PhD student at the University of the Free State (UFS), has secured a remarkable victory in the esteemed National 3 Minute Thesis competition (3MT), rising above formidable competition nationwide. This achievement follows Mogotsi’s earlier successes at faculty and institutional levels, where his presentations on the enteric virome of infants in the Free State stood out for their brilliance and significance.

The annual competition serves as a platform for postgraduate students to enhance their academic, presentation, and research communication skills by succinctly explaining their research to an intelligent but non-specialist audience within a concise 3-minute timeframe.

Reflecting on his initial reaction to the news, Mogotsi expressed a mix of shock and excitement. “I was genuinely shocked and excited when declared the winner,” he shared. This victory marked a significant milestone for Mogotsi, as a first-time participant, showcasing the excellence of both the UFS and the Faculty of Health Sciences.

Exploring uncharted territories

Mogotsi’s groundbreaking research delves into the unexplored domain of the enteric virome in infants, a subject inspired by his earlier master’s study in microbiology. “I was first introduced to this research during my master’s degree, and compelling findings motivated me to pursue further studies,” explained Mogotsi. Guided by his mentor, Prof Martin Nyaga, Mogotsi's doctoral journey unfolded into a profound exploration of the complexities of viruses colonising infants' guts and their implications on infant health.

Sharing key findings, Mogotsi highlighted that, despite detecting several disease-causing viruses in infants’ guts, none exhibited clinical symptoms. This emphasises the role of immunity and protective measures like breastfeeding. He also identified plant viruses, potentially transmitted through the environment or food sources, raising intriguing questions about infants’ exposure.

His pioneering use of viral metagenomics in unravelling the enteric virome’s complexity underscored its potential in understanding human health and disease. “Viral metagenomics has become a fundamental tool, shedding light on the composition of the infant’s enteric virome,” explained Mogotsi. 

Navigating challenges

Despite challenges, including disruptions due to COVID-19 and participant withdrawals, Mogotsi persevered, underscoring the importance of a longitudinal approach in comprehending the infant virome’s development over time. His success in the competition not only boosted his confidence but also expanded his networks, providing invaluable opportunities to present his findings internationally.

Mogotsi's advice to aspiring researchers mirrors his own journey: clarity of purpose, resilience in the face of challenges, fostering mentor relationships, and making the most of available resources. His groundbreaking work is poised to influence policy, guide vaccine strategies, and reshape our understanding of infant health.

As Mogotsi approaches the completion of his PhD, the future holds promising horizons for this trailblazing researcher, poised to leave an indelible mark on the world of virology and infant health.

News Archive

Famelab, the Pop Idols of science communication
2017-03-09

Description: Famelab Tags: UFS, CUT, Science, Competition, research, British Council, Famelab, NRF

Oluwasegun Kuloyo and Zanele Matsane proved to be
Bloemfontein’s young and wittiest science researchers.
They will represent the Free State at the Famelab
national semifinals in Johannesburg.
Photo: Oteng Mpete

Imagine sharks with laser beams attached to their heads and enzymes that wear coats, and yeasts that stage a coup d’état in your body when agitated. This was all explored at the FameLab Science Communication Competition. 

Hosting the FameLab regional competition was a collaborative effort between Dr Mikateko Hoppener, from the University of the Free State’s (UFS), the Centre for Research on Higher Education and Development (CRHED), and Edith Sempe from the Central University of Technology (CUT), Research and Development Unit. Taking place for the first time in the Free State, the event was held at the UFS Centenary Complex on 2 March 2017.

Witty minds make science fun

FameLab is a competition that promotes science and technology by creating a space for scientists to find their voices and reach public audiences. The Free State regional competition had 18 contestants and two emerged victorious on the day. Contestants had to ensure their three-minute talks were fun, charismatic, clear and entertaining.

The two regional winners were Oluwasegun Kuloyo, a PhD student with the department of Microbial Biochemical and Food Biotechnology at UFS, and Zanele Matsane, a Construction Management PhD student at CUT. 

Kuloyo's research deals with the management of the candida yeast which exists in most people’s bodies and which, with a healthy immune system can be kept under control, but when an immune system is compromised, the yeast reacts volatilely and can potentially lead to death in HIV/AIDS patients. 

Matsane’s research is centred on collaborative construction management inspired by the Toyota manufacturing process. She hopes to resolve the silos of construction and bring about a more harmonious and fluid process to construction projects, thus ensuring their successful completion. 

The panel of judges consisted of Oteng Mpete UFS Media Liaison Officer, Dr Elizabeth Conradie from the CUT Innovation Hub, and Prof Willie du Preez from the CUT Centre for Rapid Prototyping and Manufacturing, as well as Robert Inglis from JiveMedia Africa.

Local scientists become jet-setters 
The two regional winners will head to Johannesburg to compete at the FameLab national semifinals, and the South African winner will go on to compete against winners from over 30 countries on an international stage, at the Cheltenham Science Festival in the UK.

FameLab is a programme of the Cheltenham Science Festival and is implemented locally by the South African Agency for Science and Technology Advancement (SAASTA), the British Council, and JiveMedia Africa. The competition has been running in South Africa for the past five years.

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