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22 February 2023 | Story Leonie Bolleurs | Photo Supplied
Rodney Moffett
Prof Rodney Moffett was presented with the Silver Medal Award. At the ceremony were, from the left: Prof Glynis Goodman-Cron, SAAB President, Prof Rodney Moffett, and Prof Sandy-Lynn Steenhuisen.

Prof Rodney Moffett, Honorary Research Fellow in the Department of Plant Sciences at the University of the Free State (UFS) and Top Research Fellow in the Afromontane Research Unit (2018-2019) on the UFS Qwaqwa Campus, was recently awarded a Silver Medal from the South African Association of Botanists (SAAB) at their 48th annual conference that took place in Polokwane.

Prof Sandy-Lynn Steenhuisen, Subject Head and Associate Professor in the Department of Plant Sciences on the UFS Qwaqwa Campus, says, “It was an absolute joy and honour to be able to nominate and present a SAAB Silver Medal to Prof Moffett, who is an iconic figure and friend in our department. I was so happy that he could receive his award in person, with his daughter visiting from the United Kingdom. He inspires my research group so much with his knowledge of plants of the Eastern Free State and through the wealth of specimens he’s contributed to the QWA herbarium.”

The conference with the theme, ‘Plants, Health and Prosperity’, was hosted by the University of Limpopo’s Faculty of Science and Agriculture under the School of Molecular and Life Sciences in the Department of Biodiversity.

Outstanding research contributions 

According to Prof Steenhuisen, Prof Moffett received the Silver Medal Award for his outstanding research that contributed to the advancement of botany and plant sciences in South Africa.

Since his retirement, Prof Moffett has published a number of book chapters, books, reports, and articles on various aspects of fauna and flora. 

He sole-authored eight books and authored/co-authored more than 36 peer-reviewed articles in scientific journals covering mainly the taxonomy of plant genera such as Sarcocaulon, Rhus, and Searsia, and checklists of vascular plants and their medicinal uses for the Qwaqwa and Lesotho regions. 

Around 2006, Prof Moffett pursued his passion to document and describe the ethnobotanical uses of plants used by the Basotho people of Lesotho and South Africa. His books focused, for instance, on the natural history and Sesotho names of the plants used by the Basotho of the Eastern Free State and their ethnobotanical uses, the taxonomic works on the grasses of the Eastern Free State (still the most detailed grass identification guide for the area to date), and the flora and fauna of the Clarens Village Conservancy (a field guide). 

Prof Moffett has also published a scientific bibliography of the Drakensberg, Malotis and adjacent lowlands, which Prof Steenhuisen describes as “a mammoth task and one which he is continually updating and expanding, with another volume in preparation”.

Prof Steenhuisen, who nominated Prof Moffett for the Silver Medal Award, says that as a highly respected naturalist in the Qwaqwa region, he is continually consulted by conservation authorities, researchers, and postgraduate students on the flora of the area. He also regularly presents his research at garden and botanical societies. 

Among the books he has published are Sesotho names of plants and animals and plants used by the Basotho (2010), A biographical dictionary of contributors to the natural history of the Free State and Lesotho (2014), and Meriana ya dimela tsa Basotho – Basotho medicinal plants (2016 and 2020). In 2020, he also published A Scientific Bibliography of the Drakensberg, Maloti and adjacent Lowlands.

Prof Steenhuisen states that Prof Moffett’s books are treasured resources for anyone working in the Maloti-Drakensberg area. 

Best poster presentation

Joining researchers, postgraduate students, and experts from other universities and organisations at the conference, was the Plant Ecology Research Group of Prof Steenhuisen, her postgraduate students, and a postdoctoral fellow involved in invasive species and climate change research. Postgraduates from three other research groups (Plant Biotechnology, Proteomics, and Ethnobotany supervised by Dr Arun Gokul, Dr Rudo Ngara, and Prof Anofi Ashafa) on the Qwaqwa Campus also attended the conference. 

Dr Makoena Moloi, Senior Lecturer in the Department of Plant Sciences on the Bloemfontein Campus, and her postgraduate students researching aspects of plant ecophysiology, were also present at the conference, together with master’s candidate Orateng Sedimo, who is supervised by Dr Lize Joubert, Senior Lecturer in the department. Sedimo presented his honours research and won a prize for presenting the best Honours poster in the category Molecular Systematics. 

Besides being well-represented at the 48th SAAB annual conference and being awarded for its outstanding contributions to botany and plant sciences, academics from the UFS had the opportunity to learn from and network with some of the best scientists in the field. This included A1-rated scientist, Prof Steven Johnson from the University of KwaZulu-Natal, (Prof Steenhuisen’s supervisor for her PhD), and B2-rated Prof Anton Pauw from Stellenbosch University. Prof Johnson and Prof Pauw were respectively awarded a Gold and second Silver Medal from SAAB. 

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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