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22 February 2023 | Story Leonie Bolleurs | Photo Supplied
Rodney Moffett
Prof Rodney Moffett was presented with the Silver Medal Award. At the ceremony were, from the left: Prof Glynis Goodman-Cron, SAAB President, Prof Rodney Moffett, and Prof Sandy-Lynn Steenhuisen.

Prof Rodney Moffett, Honorary Research Fellow in the Department of Plant Sciences at the University of the Free State (UFS) and Top Research Fellow in the Afromontane Research Unit (2018-2019) on the UFS Qwaqwa Campus, was recently awarded a Silver Medal from the South African Association of Botanists (SAAB) at their 48th annual conference that took place in Polokwane.

Prof Sandy-Lynn Steenhuisen, Subject Head and Associate Professor in the Department of Plant Sciences on the UFS Qwaqwa Campus, says, “It was an absolute joy and honour to be able to nominate and present a SAAB Silver Medal to Prof Moffett, who is an iconic figure and friend in our department. I was so happy that he could receive his award in person, with his daughter visiting from the United Kingdom. He inspires my research group so much with his knowledge of plants of the Eastern Free State and through the wealth of specimens he’s contributed to the QWA herbarium.”

The conference with the theme, ‘Plants, Health and Prosperity’, was hosted by the University of Limpopo’s Faculty of Science and Agriculture under the School of Molecular and Life Sciences in the Department of Biodiversity.

Outstanding research contributions 

According to Prof Steenhuisen, Prof Moffett received the Silver Medal Award for his outstanding research that contributed to the advancement of botany and plant sciences in South Africa.

Since his retirement, Prof Moffett has published a number of book chapters, books, reports, and articles on various aspects of fauna and flora. 

He sole-authored eight books and authored/co-authored more than 36 peer-reviewed articles in scientific journals covering mainly the taxonomy of plant genera such as Sarcocaulon, Rhus, and Searsia, and checklists of vascular plants and their medicinal uses for the Qwaqwa and Lesotho regions. 

Around 2006, Prof Moffett pursued his passion to document and describe the ethnobotanical uses of plants used by the Basotho people of Lesotho and South Africa. His books focused, for instance, on the natural history and Sesotho names of the plants used by the Basotho of the Eastern Free State and their ethnobotanical uses, the taxonomic works on the grasses of the Eastern Free State (still the most detailed grass identification guide for the area to date), and the flora and fauna of the Clarens Village Conservancy (a field guide). 

Prof Moffett has also published a scientific bibliography of the Drakensberg, Malotis and adjacent lowlands, which Prof Steenhuisen describes as “a mammoth task and one which he is continually updating and expanding, with another volume in preparation”.

Prof Steenhuisen, who nominated Prof Moffett for the Silver Medal Award, says that as a highly respected naturalist in the Qwaqwa region, he is continually consulted by conservation authorities, researchers, and postgraduate students on the flora of the area. He also regularly presents his research at garden and botanical societies. 

Among the books he has published are Sesotho names of plants and animals and plants used by the Basotho (2010), A biographical dictionary of contributors to the natural history of the Free State and Lesotho (2014), and Meriana ya dimela tsa Basotho – Basotho medicinal plants (2016 and 2020). In 2020, he also published A Scientific Bibliography of the Drakensberg, Maloti and adjacent Lowlands.

Prof Steenhuisen states that Prof Moffett’s books are treasured resources for anyone working in the Maloti-Drakensberg area. 

Best poster presentation

Joining researchers, postgraduate students, and experts from other universities and organisations at the conference, was the Plant Ecology Research Group of Prof Steenhuisen, her postgraduate students, and a postdoctoral fellow involved in invasive species and climate change research. Postgraduates from three other research groups (Plant Biotechnology, Proteomics, and Ethnobotany supervised by Dr Arun Gokul, Dr Rudo Ngara, and Prof Anofi Ashafa) on the Qwaqwa Campus also attended the conference. 

Dr Makoena Moloi, Senior Lecturer in the Department of Plant Sciences on the Bloemfontein Campus, and her postgraduate students researching aspects of plant ecophysiology, were also present at the conference, together with master’s candidate Orateng Sedimo, who is supervised by Dr Lize Joubert, Senior Lecturer in the department. Sedimo presented his honours research and won a prize for presenting the best Honours poster in the category Molecular Systematics. 

Besides being well-represented at the 48th SAAB annual conference and being awarded for its outstanding contributions to botany and plant sciences, academics from the UFS had the opportunity to learn from and network with some of the best scientists in the field. This included A1-rated scientist, Prof Steven Johnson from the University of KwaZulu-Natal, (Prof Steenhuisen’s supervisor for her PhD), and B2-rated Prof Anton Pauw from Stellenbosch University. Prof Johnson and Prof Pauw were respectively awarded a Gold and second Silver Medal from SAAB. 

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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