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20 February 2023 | Story Gerda-Marié van Rooyen | Photo Supplied
Nthabiseng (JahRose) Jafta, a Publishing Coordinator at the University of the Free State (UFS), recently received the Silver Medal Award and other accolades at the Eurasian Literary Festival held in Egypt. She says writing is a way of life for her and she writes anywhere and anytime.

Nthabiseng (JahRose) Jafta, a Publishing Coordinator at African Languages Press in the Library and Information Services at the University of the Free State (UFS), recently received the Silver Medal Award and other accolades at the Eurasian Literary Festival held in Egypt. Jafta, an MA scholar (Creative Writing) at Rhodes University, describes herself as an international performing poet, artpreneur, teacher, festival curator, content developer, and creative strategist born in the Free State.

Being an introvert, she says her love for writing gives her a voice. “I can echo my thoughts and colour my grey sky,” she explains poetically. She feels writing is as natural to her as breathing. She is comfortable writing anywhere and anytime. “There’s no physical area needed. We type on WhatsApp in the taxi. We catch brainwaves whenever they appear.” Jafta's creative juices seem to be overflowing, as she confessed to even getting an idea while contemplating her love for writing. “Life throws you prompts from all spheres, but you have to be present to recognise its call. And sometimes the piece decides if it wants to be happy, erotic, or sad.”
 
Her literacy cap serves Jafta's career as a publisher and her creative writing when time allows. “I read and write. Publish what I read or write. I also happen to recite, read, and sing what I write. It’s all in alignment.” This Deputy President of the National Writers Association of South Africa and founder of the Poetic Blues Virtual Festival writes in her mother tongue, Sesotho, and English. She also has additional experience in the poetry industry, as she was previously the Curator of the Macufe Poetry Festival. She also attended the International Writing Centre at Beijing Normal University part time. Her poems have also been translated into Mandarin and published in Chinese literary magazines.

Jafta says besides the growing catalogue of more than 40 publications, she also has an upcoming multilingual poetry compilation featuring Spanish, Danish, Mandarin, Arabic, KiSwahili, IsiZulu, and Sesotho translations from English. This poet believes poetry is a gift that feeds lyrics to melodies. “And that song carries us to humanity's highs and lows. Prose is how we navigate that gift daily. They are rainbows on melting clouds, events plants rejoice on their rhythmic drops.”

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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