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17 July 2023 | Story NONSINDISO QWABE | Photo Supplied
Buhle Hlatshwayo
Buhle Hlatshwayo has been selected for the 2023 Fulbright Foreign Language Teaching Assistant (FLTA) Programme.

Buhle Hlatshwayo, a master’s student on the UFS Qwaqwa Campus, has been selected for the 2023 Fulbright Foreign Language Teaching Assistant (FLTA) programme. Despite initially doubting herself, she took a leap of faith and applied for the programme, which turned out to be a successful decision. The Fulbright Programme is a prestigious scholarship programme that provides opportunities for international educational exchanges. The programme’s overarching aim is to enhance intercultural relations across more than 160 countries.

Hlatshwayo will be teaching isiZulu at the University of Georgia in Athens, Georgia, for an academic year. She leaves South Africa at the end of July.

Hlatshwayo is currently pursuing her Master of Arts with specialisation in English on the UFS Qwaqwa Campus, where she also completed her undergraduate and honours degrees in the same field. Her research focuses on East African Arab migration narratives to the Global North, with a focus on exploring the legacies of colonialism. She is also a learning facilitator in the same department.

A prestigious opportunity 

A friend and colleague, Mxolisi Mabaso, encouraged her to apply, knowing her desire to explore opportunities abroad. 

“I am still in awe of how this opportunity came about, especially because someone else saw potential in me while I didn’t believe in myself. My good friend pushed me to apply, because he knew I always wanted the opportunity to go abroad. I am thrilled and honoured to be part of this prestigious programme. I am looking forward to experiencing the US culture and ways of being.”

On her love for English, Hlatshwayo said she has always been fond of the subject but never considered it as a potential career path. After completing her undergraduate degree, Dr Kudzayi Ngara, a Senior Lecturer in the Department of English on the Qwaqwa Campus, encouraged her to pursue an honour’s degree in English, which ultimately shaped her academic journey.

Professional and personal growth awaits

While in the US, Hlatshwayo said she is looking forward to immersing herself in American culture and pursuing courses in American studies. She aims to learn more about diverse cultural backgrounds and share her South African heritage and cultural values with the international community. She said this exchange of experiences and ideas will broaden her horizons and contribute to her academic and professional development.

“The opportunities would not present themselves if you were not capable. If you know your goals, seize any opportunity that will enable you to get there. I was not granted this opportunity because I’m smarter than everyone else, but because of how I articulated my genuine motivations with future goals and how the Fulbright programme will help me achieve them,” she said.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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