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29 June 2023 | Story Dr Ina Gouws | Photo Supplied
Dr Ina Gouws
Dr Ina Gouws is a Senior Lecturer in the Department of Political Studies and Governance

University of the Free State

We find ourselves on the other side of another Youth Day in South Africa. I acknowledge the importance of this anniversary, although I recognise that it is not for me to fully comprehend the profound significance of commemorating the events of 16 June 1976. I therefore refrain from presuming to address the depth of pain, both enduring and otherwise, that this commemoration signifies.

Let me then stay with the broader significance of Youth Month in my deliberations.

Cabinet approved the theme for Youth Month 2023 to be: “Accelerating youth economic emancipation for a sustainable future”. In 2022 the theme was: “Promoting sustainable livelihood and resilience of young people for a better tomorrow”, and, in 2021 the theme was:  “The Year of Charlotte Mannya Maxeke: Growing youth employment for an inclusive and transformed society”.

Cooperation and partnership between government and the youth is fractured

For a government known for abject failure especially regarding education and economic policy, these are lofty ambitions for which we have not seen positive results. I fear that most of our country’s youths are not aware of these themes or else take note with understandable cynicism.  The trust they should have in our government to expect positive outcomes for policies and plans simply does not exist. The cooperation and partnership that needs to be forged between government and the youth in South Africa is therefore fractured to say the least. Consequently, a sense of disillusionment has taken hold.

Feelings of marginalisation and being unheard have bred disengagement, apathy, and even resentment. It appears this government can only talk a great game. None of this is news, is it? The problem is that the breakdown in trust undermines the foundation of a healthy democracy, hindering the government’s ability to effectively represent and address the needs of our youth. The effect of this failure has disastrous consequences for young people to the very core of their dignity.

It is therefore crucial to recognise the profound human consequences that come with unemployment and dire prospects. The impact of unemployment on young individuals is not to be underestimated or only boxed into aspects of economics, as it significantly disrupts their sense of self and place in the world way beyond that. I believe the approach in South Africa should therefore also recognise the intrinsic value and dignity of the youth beyond their economic productivity. As it is,  I fear they have ended up finding their self-worth in only ever being prone to confrontation and protest, instead of constructive problem-solving. It is then no surprise that a grim view of the future can hinder the formation of new social connections and limit opportunities for networking, further exacerbating the isolation experienced by unemployed youth which feeds this apathy and disinterest the majority seem to have in the political process.

What is to be done?

I don’t see any purely political drive or approach to provoke widespread youth participation being successful in this context. What is to be done? We must start with ways to create ‘willingness’ first. For that, purpose beyond politics, in which they have lost trust and interest, is necessary. I have no doubt that the country’s youth care about their communities even if they feel disconnected and have little to offer to assist because of their dire socio-economic realities. We must create spaces for dialogue, storytelling, and collective reflection to challenge societal narratives surrounding work and success, promoting alternative measures of value and worth. Emphasising the importance of empathy, compassion, and community solidarity can help combat the stigmatisation and isolation faced by unemployed youth.

Moreover, recognising the agency and potential of young people is essential for the nation's future development and prosperity. It would be best to first focus on independent initiatives and collaborations outside of the government’s sphere of influence. Emphasising grassroots movements, civil society organisations, and community-led efforts that can drive change from the bottom up, could get the youth involved without focusing on politics alone. By focusing on initiatives that bypass or work independently of the government, youth can still actively participate and work towards their goals, and I believe that willingness to participate lies just below the surface.

Change will take time

The challenge, and perhaps frustration, is to recognise that long-term perspective and focus on building a sustainable foundation for youth political engagement will be necessary. With the damage that has been done, change will take time and involve continuous efforts beyond any specific government’s tenure. And relying so heavily on any community’s resilience should be seriously questioned, especially when it comes to the youth. There must be a more positive outcome than what they have thus far lived, after showing such perseverance. I believe we can help recover a willingness in our youth to again or for the first time participate in constructive ways to promote necessary change for themselves and their communities beyond a day or a month; for a lifetime.

News Archive

Cardiology Unit involved in evaluation of drug for rare genetic disease
2013-01-04

Front from the left, are: Marinda Karsten (study coordinator and registered nurse),
Laumarie de Wet (clinical technologist), Charmaine Krahenbuhl (study coordinator and radiographer),
Lorinda de Meyer (administrator), Andonia Page (study coordinator and enrolled nurse);
back Dr Gideon Visagie (sub investigator), Dr Derick Aucamp (sub investigagtor),
Prof. Hennie Theron, (principal investigator) and Dr Wilhelm Herbst (sub investigator).
Photo: Supplied
09 January 2013


The Cardiology Research Unit at the University of the Free State (UFS) contributed largely to the evaluation of the drug Juxtapid (lomitapide), which was developed by the Aegerion pharmaceutical company and approved by the FDA (Federal Drug Administration). Together with countries such as die USA, Canada and Italy, the UFS’ Unit recruited and evaluated the most patients (5 of 29) for the study since 2008.  

The drug was evaluated in persons with so-called familial homozygous hypercholesterolemia (HoFH).  

Following its approval by the FDA, Juxtapid is now a new treatment option for patients suffering from HoFH. The drug operates in a unique way which brings about dramatic improvements in cholesterol counts.  

According to Prof. Hennie Theron, Associate Professor in the Department of Cardiology at the UFS and Head of the Cardiology Contract Research Unit, HoFH is a serious, rare genetic disease which affects the function of the receptor responsible for the removal of low-density lipoprotein cholesterol (LDL-C) (“bad” cholesterol) from the body. Damage to the LDL receptor function leads to extremely high levels of blood cholesterol. HoFH patients often develop premature and progressive atherosclerosis, which is a narrowing or blockage of the arteries.  

“HoFH is a genetically transmitted disease and the most severe form of hypercholesterolemia. Patients often need a coronary artery bypass or/and aortic valve replacement before the age of 20. Mortality is extremely high and death often occurs before the third decade of life. Existing conventional cholesterol-lowering medication is unsuccessful in achieving normal target cholesterol values in this group of patients.  

“The only modality for treatment is plasmapheresis (similar to dialysis in patients with renal failure). Even with this type of therapy the results are relatively unsatisfactory because it is very expensive and the plasmapheresis has to be performed on a regular basis.  

“The drug Juxtapid, as currently evaluated, has led to a dramatic reduction in cholesterol values and normal values were achieved in several people. No existing drug is nearly as effective.  

“The drug represents a breakthrough in the treatment of familial homozygous hypercholesterolemia. The fact that it has been approved by the FDA, gives further impetus to the findings,” says Prof. Theron.  

In future further evaluation will be performed in other forms of hypocholesterolemia.  

According to Prof. Theron, the findings of the study, as well as the recent successful FDA evaluation, once again confirms the fact that the UFS’ Cardiology Contract Research Unit is doing outstanding work.  

Since its inception in 1992, the Unit has already been involved in more than 60 multi-centre, international phase 2 and 3 drug studies. Several of these studies, including the abovementioned study, really affected the way in which cardiology functions.  

The UFS’ Cardiology Contract Research Unit is being recognised nationally and internationally for its high quality of work and is constantly approached for their involvement in new studies.  

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