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Thought-Leader Series: A culture of acceptance – is this South Africa’s greatest threat?

12 June 2023 | Story Samkelo Fetile

2023 UFS Thought-Leader Series

PRESENTS

a panel discussion titled

A culture of acceptance – is this South Africa’s greatest threat?

Watch the livestream (live on 13 July 2023)

The University of the Free State is pleased to announce the upcoming UFS Thought-Leader panel discussion titled “A Culture of Acceptance – South Africa’s Greatest Threat?” as part of the 2023 Thought-Leader Series. A public South African higher-education institution, The University of the Free State (UFS) recognises its responsibility to contribute to the public discourse. In collaboration with the Free State Literature Festival, this event will bring together esteemed thought leaders to shed light on the social, political, economic, and business landscape of South Africa and its implications for our future. The panel discussion will be facilitated by Prof Francis Petersen, Vice-Chancellor and Principal of the UFS.

Panel discussion presented on 13 July 2023

The general state of decay we are currently experiencing in our various structures of governance on nearly all levels is preventing the economic growth that our country so desperately needs to move forward. Our current national financial status is clearly the result of not only poor government performance, but also a totally deficient policy environment. Part of the threats currently facing our country is civil society’s attitude of accepting rampant corruption, crime, and economic degradation as if it is something inevitable and unavoidable. The question is: has our current situation created a society that has simply accepted its fate? Or has it created a society that has become more innovative and creative, actively navigating current challenges, and finding new solutions to societal issues independent of government? These are some of the aspects we look forward to discussing with the esteemed panel.

Date:	Thursday 13 July 2023
Time:	10:00-12:00
Venue:	Albert Wessels Auditorium, Bloemfontein Campus
RSVP:	https://events.ufs.ac.za/e/ThoughtLeaderPanel by 10 July 2023

Refreshments will be served.

For further information, contact Alicia Pienaar at pienaaran1@ufs.ac.za.

Some of the topics discussed by leading experts in 2022 included, among others, Crime in South Africa – who is to blame; Are our glasses half full or half empty; What needs to be done to power up South Africa?; and A look into the future of South Africa. This year’s webinar series commenced in April, when we discussed Threats to South Africa’s stability and security challenges.

Facilitator:	Prof Francis Petersen	Vice-Chancellor and Principal, UFS

Panellists:	Prof Bonang Mohale	President: Business Unity South Africa

	Prof Piet Croucamp	Senior Lecturer, Political Studies and International Relations: North-West University

	Dr Sipho Pityana	Founder and Chairman: Izingwe Capital (Pty) Limited

	Dr Lindie Koorts	Research Fellow: International Studies Group, UFS

Bios of speakers:

Prof Bonang Mohale

Bonang Mohale is the President of Business Unity South Africa (BUSA), Chancellor of the University of the Free State, Professor of Practice in the Johannesburg Business School (JBS) College of Business and Economics and Chairman of The Bidvest Group Limited, SBV Services and ArcelorMittal! He is a member of the Community of Chairpersons (CoC) of the World Economic Forum.

Mohale, a highly respected South African businessman, has held several leadership positions; namely, CEO of Business Leadership South Africa (BLSA), Vice President and Chairman of Shell South Africa (Pty) Ltd, Executive Vice President of SAA and MD of Otis (Pty) Ltd, among others. A vocal, agent courageous change, Mohale is known for his patriotism and active role in advancing the interests of South Africa. Mohale has a distinguished career and track record of leading and building successful companies and making significant advances in the transformation of these companies.

An avid writer, Mohale is the author of the bestselling books, “Lift As You Rise“ and “Behold The Turtle” which contain and reveals the issues he is passionate about. Mohale has been included in the Reputation Poll International’s (RPI) 2023 list of the ‘100 Most Reputable Africans’. The selection criteria are Integrity, Reputation, Transparency, Visibility, and Impact.

Prof Piet Croucamp

Professor Piet Croucamp teaches politics at the North-West University. His research interest is the social origins of violence. He has published extensively in both national and international scholarly journals.

Dr Sipho Pityana

Dr Sipho Mila Pityana is a business leader with extensive experience, having served in both executive and non-executive capacities on several local and international boards of blue-chip companies. He is the founder and Chairman of his private investment firm Izingwe. He is currently Chairman of the JSE-listed Redefine Properties, and non-executive Director of the Absa Bank Group. He is the former Chairman of AngloGold Ashanti Limited, and Munich Re of Africa. He also served as a lead independent Director of the Absa Group and an executive director of Nedcor Investment Bank, among others. He was the founding delegate of the National Economic Development and Labour Council (NEDLAC), and he was one of the founding members of the governing body of the Commission for Conciliation, Mediation and Arbitration. He served on the governing body of the International Labour Organisation (ILO). His passion for education has seen him serve as Registrar of the University of Fort Hare, Chairperson of the National Student Financial Aid Scheme (NSFAS), and former Chairperson of the Council of the University of Cape Town.

Dr Lindie Koorts

Dr. Lindie Koorts is a historian, biographer and author. She is a Research Associate at the University of the Free State's International Studies Group and a regular media commentator, who often writes on the links between current affairs and history.

Livestream

WATCH: 2023 UFS Thought-Leader Series (Live on 13 July 2023)

News Archive

Research contributes to improving quality of life for cancer patients

2016-11-21

Description: Inorganic Chemistry supervisors Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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