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07 June 2023 | Story André Damons | Photo Supplied
Prof Champion Nyoni and Prof Motlalepula Matsabisa
Prof Champion Nyoni, Senior Researcher in the School of Nursing at the University of the Free State (UFS). Prof Motlalepula Matsabisa, an African traditional medicine expert and Head of the African Medicines Innovations and Technologies Development Platform (AMITD) within the UFS Department of Pharmacology.

Prof Champion Nyoni, Senior Researcher in the School of Nursing at the University of the Free State (UFS), has been appointed to the World Health Organisation (WHO) Academy Standing Advisory Quality Committee – making him the only representative from Africa to serve in this academy.

Another UFS staff member, Prof Motlalepula Matsabisa, an expert on African traditional medicine and Head of the African Medicines Innovations and Technologies Development Platform (AMITD) within the Department of Pharmacology, has also been appointed to serve on a WHO initiative – the WHO Global Centre for Traditional Medicine Editorial Board/Evidence Task Force. His appointment will be effective until the end of December 2023.

Prof Matsabisa will also attend the first WHO Traditional Medicine Global Summit in India in August 2023, after being invited to serve as a member of the Summit External Advisory Group for the WHO Traditional Medicine Global Summit (‘Advisory Group’).

The appointment of Prof Nyoni, who is the current Chairperson of the Board of Directors for the Africa Interprofessional Education Network (AfrIPEN), and Deputy Chair of the Board for Interprofessional.Global a global confederation of interprofessional networks based in the Netherlands – will be effective for two years.

The WHO Academy is a priority initiative of the WHO transformation agenda and will support accelerated learning and skills recognition of staff and external stakeholders to advance the implementation of the WHO's strategic plan and ‘triple billion’ goal: ensuring that by 2023, an additional one billion people benefit from universal health coverage; one billion more are afforded better protection in health emergencies, and one billion more enjoy improved health and well-being.

Work and contribution being recognised

“I feel thrilled about this exciting adventure. I think this is an exciting opportunity in my career to be recognised by an organisation such as the WHO to serve in the capacity of adviser. I think this is a huge feather in my cap, our School of Nursing, and the faculty. My work and contribution are being recognised and this is a good thing. I am hoping to make an impact in this committee and to also learn from it,” says Prof Nyoni.

Even though there is a bit of pressure representing the whole continent, Prof Nyoni believes his experience with global organisations will come in handy. He is ready to take on the challenge, give it his best, and leave a legacy of excellence.

“Due to the complexity of health professions education in our context, our different cultural, geographical, and socio-economic issues, it is truly an interesting concept to actually think of representing an entire region. I have worked in and continue to work in many countries in Africa through various research projects and postgraduate students, which gives one some insight into what is happening in the region, but often one needs to know more.”

Global knowledge centre for traditional medicine

For Prof Matsabisa, who is also the chairperson of the WHO Regional Expert Advisory Committee on Traditional Medicine (REACT), it is always thrilling to be recognised by serving in such world bodies.

The WHO Global Centre for Traditional Medicine (WHO-GCTM) was established in 2022 as a global knowledge centre for traditional medicine to harness the potential of traditional medicine from across the world through modern science and technology in order to improve the health of people and the planet.

“I look at myself most of the time and ask myself what I am doing right to be given such recognition globally. I am, however, always ready and prepared to take such responsibilities and challenges. I feel happy and great knowing that my expertise and experience is recognised so far from home. I will do my best and try not to fail anyone. I will give it my all and put my whole heart into this task,” says Prof Matsabisa.

He looks forward to seeing the WHO develop tools and guidelines that will promote the institutionalisation of traditional medicine and to come up with positive resolutions on how to take traditional medicines forward.

World takes traditional medicine seriously

According to Prof Matsabisa, the world is now taking traditional medicines seriously. The developed world is now serious about using traditional medicines for their daily health needs and consumption. The world is accepting the positive and important role that traditional medicine is playing in our health-care needs and how it is contributing to the health and well-being of people.

“It is unfortunate that, at home, we have sceptics and people still living in the past who are blind to the importance of traditional medicines. The WHO is now seriously taking the lead in giving advice and guidelines on traditional medicines. It makes me very happy to see these significant movements around traditional medicines."

Africa, Prof Matsabisa concludes, still has its natural resources and its indigenous knowledge as the main remaining tools to get the continent into development and economic freedom. If strategic decisions could be made around developments based on the natural resources for local beneficiation and moving away from the ‘thinking about resources’ to a knowledge-based economy, we could take the continent out of poverty, famine, and wars, and redirect resources to development, technical skills development, and wealth generation for all.

News Archive

Research eradicates bacteria from avocado facility
2017-01-17

 Description: Listeria monocytogenes Tags: Listeria monocytogenes

Listeria monocytogenes as seen under an electron
microscope. The photo was taken with a transmission
electron microscope at the microscopy unit of the UFS.
Bacteriophages (lollipop-like structures) can be seen
next to the bacterial cells.
Photo: Supplied

“The aim of my project was to identify and characterise the contamination problem in an avocado-processing facility and then to find a solution,” said Dr Amy Strydom, postdoctoral fellow in the Department of Microbial Biochemical and Food Biotechnology at the University of the Free State (UFS).

Her PhD, “Control of Listeria monocytogenes in an Avocado-processing Facility”, aimed to identify and characterise the contamination problem in a facility where avocados were processed into guacamole. Dr Strydom completed her MSc in food science in 2009 at Stellenbosch University and this was the catalyst for her starting her PhD in microbiology in 2012 at the UFS. The research was conducted over a period of four years and she graduated in 2016. The research project was funded by the National Research Foundation.

The opportunity to work closely with the food industry further motivated Dr Strydom to conduct her research. The research has made a significant contribution to a food producer (avocado facility) that will sell products that are not contaminated with any pathogens. The public will then buy food that is safe for human consumption.


What is Listeria monocytogenes?

Listeria monocytogenes is a food-borne pathogenic bacterium. When a food product is contaminated with L. monocytogenes, it will not be altered in ways that are obvious to the consumer, such as taste and smell. When ingested, however, it can cause a wide range of illnesses in people with impaired immune systems. “Risk groups include newborn babies, the elderly, and people suffering from diseases that weaken their immune systems,” Dr Strydom said. The processing adjustments based on her findings resulted in decreased numbers of Listeria in the facility.

The bacteria can also survive and grow at refrigeration temperatures, making them dangerous food pathogens, organisms which can cause illnesses [in humans]. Dr Strydom worked closely with the facility and developed an in-house monitoring system by means of which the facility could test their products and the processing environment. She also evaluated bacteriophages as a biological control agent in the processing facility. Bacteriophages are viruses that can only infect specific strains of bacteria. Despite bacteriophage products specifically intended for the use of controlling L. monocytogenes being commercially available in the food industry, Dr Strydom found that only 26% of the L. monocytogenes population in the facility was destroyed by the ListexP100TM product. “I concluded that the genetic diversity of the bacteria in the facility was too high and that the bacteriophages could not be used as a control measure. However, there is much we do not understand about bacteriophages, and with a few adjustments, we might be able to use them in the food industry.”

Microbiological and molecular characterisation of L. monocytogenes

The bacteria were isolated and purified using basic microbiological culturing. Characterisation was done based on specific genes present in the bacterial genome. “I amplified these genes with polymerase chain reaction (PCR), using various primers targeting these specific genes,” Dr Strydom said. Some amplification results were analysed with a subsequent restriction digestion where the genes were cut in specific areas with enzymes to create fragments. The lengths of these fragments can be used to differentiate between strains. “I also compared the whole genomes of some of the bacterial strains.” The bacteriophages were then isolated from waste water samples at the facility using the isolated bacterial strains. “However, I was not able to isolate a bacteriophage that could infect the bacteria in the facility.

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